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The typically rugged nature of molecular free energy landscapes can frustrate efficient sampling of the thermodynamically relevant phase space due to the presence of high free energy barriers. Enhanced sampling techniques can improve phase…

Biomolecules · Quantitative Biology 2023-08-21 Nicholas S. M. Herringer , Siva Dasetty , Diya Gandhi , Junhee Lee , Andrew L. Ferguson

Crystallization is one of the most important physicochemical processes which has relevance in material science, biology, and the environment. Decades of experimental and theoretical efforts have been made to understand this fundamental…

Soft Condensed Matter · Physics 2022-09-29 Neha , Vikas Tiwari , Soumya Mondal , Nisha Kumari , Tarak Karmakar

Shape matching is a fundamental task in computer graphics and vision, with deep functional maps becoming a prominent paradigm. However, existing methods primarily focus on learning informative feature representations by constraining…

Computer Vision and Pattern Recognition · Computer Science 2026-03-26 Feifan Luo , Hongyang Chen

This paper proposes a dynamic network framework for uncovering latent community paths in high-dimensional VAR-type models. By embedding a degree-corrected stochastic co-blockmodel (ScBM) into the transition matrices of VAR-type systems, we…

Methodology · Statistics 2026-04-15 Younghoon Kim , Changryong Baek

The long-timescale behavior of complex dynamical systems can be described by linear Markov or Koopman models in a suitable latent space. Recent variational approaches allow the latent space representation and the linear dynamical model to…

Computational Physics · Physics 2019-12-17 Andreas Mardt , Luca Pasquali , Frank Noé , Hao Wu

Diffusion-based samplers learn to sample complex, high-dimensional distributions using energies or log densities alone, without training data. Yet, they remain impractical for molecular sampling because they are often slower than molecular…

Dynamical Systems (DS) are an effective and powerful means of shaping high-level policies for robotics control. They provide robust and reactive control while ensuring the stability of the driving vector field. The increasing complexity of…

Robotics · Computer Science 2024-03-19 Bernardo Fichera , Aude Billard

Machine learning (ML) tools such as encoder-decoder deep convolutional neural networks (CNN) are able to extract relationships between inputs and outputs of large complex systems directly from raw data. For time-varying systems the…

Accelerator Physics · Physics 2021-03-25 Alexander Scheinker , Frederick Cropp , Sergio Paiagua , Daniele Filippetto

Graph embedding techniques are useful to characterize spectral signature relations for hyperspectral images. However, such images consists of disjoint classes due to spatial details that are often ignored by existing graph computing tools.…

Computer Vision and Pattern Recognition · Computer Science 2012-11-29 Dalton Lunga 'and' Okan Ersoy

Many biological processes occur on time scales longer than those accessible to molecular dynamics simulations. Identifying collective variables (CVs) and introducing an external potential to accelerate them is a popular approach to address…

Computational Physics · Physics 2024-10-24 Enrico Trizio , Andrea Rizzi , Pablo M. Piaggi , Michele Invernizzi , Luigi Bonati

Graphs are ubiquitous data structures for representing interactions between entities. With an emphasis on the use of graphs to represent chemical molecules, we explore the task of learning to generate graphs that conform to a distribution…

Machine Learning · Computer Science 2019-03-08 Qi Liu , Miltiadis Allamanis , Marc Brockschmidt , Alexander L. Gaunt

We propose an empirical approach centered on the spectral dynamics of weights -- the behavior of singular values and vectors during optimization -- to unify and clarify several phenomena in deep learning. We identify a consistent bias in…

Spatiotemporal imaging has applications in e.g. cardiac diagnostics, surgical guidance, and radiotherapy monitoring, In this paper, we explain the temporal motion by identifying the underlying dynamics, only based on the sequential images.…

Medical Physics · Physics 2024-10-16 Niklas Gunnarsson , Peter Kimstrand , Jens Sjölund , Thomas B. Schön

The availability of affordable 3D full body reconstruction systems has given rise to free-viewpoint video (FVV) of human shapes. Most existing solutions produce temporally uncorrelated point clouds or meshes with unknown point/vertex…

Computer Vision and Pattern Recognition · Computer Science 2018-10-15 Zhong Li , Minye Wu , Wangyiteng Zhou , Jingyi Yu

We extend the recently developed discrete geometric singular perturbation theory to the non-normally hyperbolic regime. Our primary tool is the Takens embedding theorem, which provides a means of approximating the dynamics of particular…

Dynamical Systems · Mathematics 2024-08-13 Samuel Jelbart , Christian Kuehn

Polynomial dynamical systems (DSs) can model a wide range of physical processes. A special subset of these DSs that can model chemical reactions under mass-action kinetics is called chemical dynamical systems (CDSs). A fundamental problem,…

Molecular Networks · Quantitative Biology 2025-08-04 Tomislav Plesa

In real-world applications with large state and action spaces, reinforcement learning (RL) typically employs function approximations to represent core components like the policies, value functions, and dynamics models. Although powerful…

Machine Learning · Computer Science 2026-01-29 Chenxiao Gao , Haotian Sun , Na Li , Dale Schuurmans , Bo Dai

Coarse-grained simulations of conjugated polymers have become a popular way of investigating the device physics of organic photovoltaics. While UV-Vis spectroscopy remains one of key experimental methods for the interrogation of these…

Disordered Systems and Neural Networks · Physics 2019-09-10 Lena Simine , Thomas C. Allen , Peter J. Rossky

Very high dimensional nonlinear systems arise in many engineering problems due to semi-discretization of the governing partial differential equations, e.g. through finite element methods. The complexity of these systems present…

Optimization and Control · Mathematics 2022-09-15 Florian Mahlknecht , John Irvin Alora , Shobhit Jain , Edward Schmerling , Riccardo Bonalli , George Haller , Marco Pavone

Crystallization, a fundamental phase transition process governing material formation in natural and industrial contexts, involves the spontaneous emergence of long-range structural order from disordered phases. This long-range periodicity…

Statistical Mechanics · Physics 2025-10-13 YaoKun Lei , MaoDong Li , Yi Isaac Yang