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Large language models (LLMs) have made significant progress in various domains, including healthcare. However, the specialized nature of clinical language understanding tasks presents unique challenges and limitations that warrant further…

Computation and Language · Computer Science 2023-08-01 Yuqing Wang , Yun Zhao , Linda Petzold

Identifying medication discontinuations in electronic health records (EHRs) is vital for patient safety but is often hindered by information being buried in unstructured notes. This study aims to evaluate the capabilities of advanced…

Computation and Language · Computer Science 2025-11-10 Chong Shao , Douglas Snyder , Chiran Li , Bowen Gu , Kerry Ngan , Chun-Ting Yang , Jiageng Wu , Richard Wyss , Kueiyu Joshua Lin , Jie Yang

Substance use disorder (SUD) poses a major concern due to its detrimental effects on health and society. SUD identification and treatment depend on a variety of factors such as severity, co-determinants (e.g., withdrawal symptoms), and…

Computation and Language · Computer Science 2024-03-20 Maria Mahbub , Gregory M. Dams , Sudarshan Srinivasan , Caitlin Rizy , Ioana Danciu , Jodie Trafton , Kathryn Knight

Large language models (LLMs) have demonstrated dominating performance in many NLP tasks, especially on generative tasks. However, they often fall short in some information extraction tasks, particularly those requiring domain-specific…

Computation and Language · Computer Science 2023-09-22 Junyi Bian , Jiaxuan Zheng , Yuyi Zhang , Shanfeng Zhu

While Large Language Models (LLMs) have exhibited remarkable emergent capabilities through extensive pre-training, they still face critical limitations in generalizing to specialized domains and handling diverse linguistic variations, known…

Computation and Language · Computer Science 2025-05-28 Jinwu Hu , Zhitian Zhang , Guohao Chen , Xutao Wen , Chao Shuai , Wei Luo , Bin Xiao , Yuanqing Li , Mingkui Tan

Automated clinical text anonymization has the potential to unlock the widespread sharing of textual health data for secondary usage while assuring patient privacy and safety. Despite the proposal of many complex and theoretically successful…

Computation and Language · Computer Science 2024-06-05 David Pissarra , Isabel Curioso , João Alveira , Duarte Pereira , Bruno Ribeiro , Tomás Souper , Vasco Gomes , André V. Carreiro , Vitor Rolla

The development of large language models (LLMs) has brought unprecedented possibilities for artificial intelligence (AI) based medical diagnosis. However, the application perspective of LLMs in real diagnostic scenarios is still unclear…

Computation and Language · Computer Science 2024-05-21 Zhoujian Sun , Cheng Luo , Ziyi Liu , Zhengxing Huang

The accurate recognition of symptoms in clinical reports is significantly important in the fields of healthcare and biomedical natural language processing. These entities serve as essential building blocks for clinical information…

Computation and Language · Computer Science 2024-01-30 Mai A. Shaaban , Abbas Akkasi , Adnan Khan , Majid Komeili , Mohammad Yaqub

Background: Manual extraction of pancreatic cystic lesion (PCL) features from radiology reports is labor-intensive, limiting large-scale studies needed to advance PCL research. Purpose: To develop and evaluate large language models (LLMs)…

Extracting structured information from clinical notes requires navigating a dense web of interdependent variables where the value of one attribute logically constrains others. Existing Large Language Model (LLM)-based extraction pipelines…

Effective communication about breast and cervical cancers remains a persistent health challenge, with significant gaps in public understanding of cancer prevention, screening, and treatment, potentially leading to delayed diagnoses and…

Computation and Language · Computer Science 2025-05-19 Agnik Saha , Victoria Churchill , Anny D. Rodriguez , Ugur Kursuncu , Muhammed Y. Idris

Purpose: In this paper, we present an automated method for article classification, leveraging the power of Large Language Models (LLM). The primary focus is on the field of ophthalmology, but the model is extendable to other fields.…

Clinical trial matching is the task of identifying trials for which patients may be potentially eligible. Typically, this task is labor-intensive and requires detailed verification of patient electronic health records (EHRs) against the…

Public health researchers are increasingly interested in using social media data to study health-related behaviors, but manually labeling this data can be labor-intensive and costly. This study explores whether zero-shot labeling using…

Computation and Language · Computer Science 2025-02-11 Kamyar Kazari , Yong Chen , Zahra Shakeri

Large Language Models (LLMs) offer significant potential for clinical symptom extraction, but their deployment in healthcare settings is constrained by privacy concerns, computational limitations, and operational costs. This study…

Clinical summarization is crucial in healthcare as it distills complex medical data into digestible information, enhancing patient understanding and care management. Large language models (LLMs) have shown significant potential in…

Computation and Language · Computer Science 2025-08-21 Anindya Bijoy Das , Shibbir Ahmed , Shahnewaz Karim Sakib

Contemporary large language models (LLMs) may have utility for processing unstructured, narrative free-text clinical data contained in electronic health records (EHRs) -- a particularly important use-case for mental health where a majority…

Artificial Intelligence · Computer Science 2024-04-01 Niall Taylor , Andrey Kormilitzin , Isabelle Lorge , Alejo Nevado-Holgado , Dan W Joyce

Graphs are pervasive in the real-world, such as social network analysis, bioinformatics, and knowledge graphs. Graph neural networks (GNNs) have great ability in node classification, a fundamental task on graphs. Unfortunately, conventional…

Machine Learning · Computer Science 2024-09-05 Quan Li , Tianxiang Zhao , Lingwei Chen , Junjie Xu , Suhang Wang

The adoption of large language models (LLMs) to assist clinicians has attracted remarkable attention. Existing works mainly adopt the close-ended question-answering (QA) task with answer options for evaluation. However, many clinical…

The application of large language models (LLMs) in healthcare has gained significant attention due to their ability to process complex medical data and provide insights for clinical decision-making. These models have demonstrated…

Computer Vision and Pattern Recognition · Computer Science 2024-09-26 Amna Khalid , Ayma Khalid , Umar Khalid