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To acquire high-quality positron emission tomography (PET) images while reducing the radiation tracer dose, numerous efforts have been devoted to reconstructing standard-dose PET (SPET) images from low-dose PET (LPET). However, the success…

Image and Video Processing · Electrical Eng. & Systems 2024-07-31 Jiaqi Cui , Pinxian Zeng , Yuanyuan Xu , Xi Wu , Jiliu Zhou , Yan Wang

Positron emission tomography (PET) is widely used in various clinical applications, including cancer diagnosis, heart disease and neuro disorders. The use of radioactive tracer in PET imaging raises concerns due to the risk of radiation…

Computer Vision and Pattern Recognition · Computer Science 2017-12-13 Junshen Xu , Enhao Gong , John Pauly , Greg Zaharchuk

As a sensitive functional imaging technique, positron emission tomography (PET) plays a critical role in early disease diagnosis. However, obtaining a high-quality PET image requires injecting a sufficient dose (standard dose) of…

Image and Video Processing · Electrical Eng. & Systems 2024-12-06 Caiwen Jiang , Mianxin Liu , Kaicong Sun , Dinggang Shen

Reducing the injected dose would result in quality degradation and loss of information in PET imaging. To address this issue, deep learning methods have been introduced to predict standard PET images (S-PET) from the corresponding low-dose…

Medical Physics · Physics 2022-02-23 Behnoush Sanaei , Reza Faghihi , Hossein Arabi

Positron Emission Tomography (PET) is an important molecular imaging tool widely used in medicine. Traditional PET systems rely on complete detector rings for full angular coverage and reliable data collection. However, incomplete-ring PET…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Yeqi Fang , Rong Zhou

Positron emission tomography (PET) scans expose patients to radiation, which can be mitigated by reducing the dose, albeit at the cost of diminished quality. This makes low-dose (LD) PET recovery an active research area. Previous studies…

Image and Video Processing · Electrical Eng. & Systems 2026-03-11 Ghulam Nabi Ahmad Hassan Yar , Himashi Peiris , Victoria Mar , Cameron Dennis Pain , Zhaolin Chen

We developed a positron emission tomography (PET) system for multiple-isotope imaging. Our PET system, named multiple-isotope PET (MI-PET), can distinguish between different tracer nuclides using coincidence measurement of prompt…

Reducing scan times, radiation dose, and enhancing image quality for lower-performance scanners, are critical in low-dose PET imaging. Deep learning techniques have been investigated for PET image denoising. However, existing models have…

Positron Emission Tomography (PET) scanners are usually designed with the goal to obtain the best compromise between sensitivity, resolution, field-of-view size, and cost. Therefore, it is difficult to improve the resolution of a PET…

Medical Physics · Physics 2023-07-18 Pablo Galve , Alejandro Lopez-Montes , Jose M Udias , Stephen C Moore , Joaquin L Herraiz

Radiation exposure in positron emission tomography (PET) imaging limits its usage in the studies of radiation-sensitive populations, e.g., pregnant women, children, and adults that require longitudinal imaging. Reducing the PET radiotracer…

Image and Video Processing · Electrical Eng. & Systems 2021-07-22 Viswanath P. Sudarshan , Uddeshya Upadhyay , Gary F. Egan , Zhaolin Chen , Suyash P. Awate

Positron Emission Tomography (PET) image reconstruction is inherently challenged by Poisson noise and physical degradation factors, which are further exacerbated in limited-angle acquisitions. While deep learning methods demonstrate…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Rüveyda Yilmaz , Yuli Wu , Johannes Stegmaier , Volkmar Schulz

To obtain high-quality positron emission tomography (PET) images while minimizing radiation exposure, various methods have been proposed for reconstructing standard-dose PET (SPET) images from low-dose PET (LPET) sinograms directly.…

Image and Video Processing · Electrical Eng. & Systems 2023-08-11 Jiaqi Cui , Pinxian Zeng , Xinyi Zeng , Peng Wang , Xi Wu , Jiliu Zhou , Yan Wang , Dinggang Shen

SPECT (Single-photon Emission Computerized Tomography) and PET (Positron Emission Tomography) are essential medical imaging tools, for which the sampling angle number, scan time should be chosen carefully to compromise between image quality…

Medical Physics · Physics 2015-06-16 Xiaolin Zhou , Minkai Yun , Xuexiang Cao , Shuangquan Liu , Lu Wang , Xianchao Huang , Long Wei

Large high-quality medical image datasets are difficult to acquire but necessary for many deep learning applications. For positron emission tomography (PET), reconstructed image quality is limited by inherent Poisson noise. We propose a…

Low-Dose computer tomography (LDCT) is an ideal alternative to reduce radiation risk in clinical applications. Although supervised-deep-learning-based reconstruction methods have demonstrated superior performance compared to conventional…

Image and Video Processing · Electrical Eng. & Systems 2024-05-24 Feng Wang , Renfang Wang , Hong Qiu

To obtain high-quality positron emission tomography (PET) scans while reducing radiation exposure to the human body, various approaches have been proposed to reconstruct standard-dose PET (SPET) images from low-dose PET (LPET) images. One…

Image and Video Processing · Electrical Eng. & Systems 2023-08-22 Zeyu Han , Yuhan Wang , Luping Zhou , Peng Wang , Binyu Yan , Jiliu Zhou , Yan Wang , Dinggang Shen

As PET imaging is accompanied by substantial radiation exposure and cancer risk, reducing radiation dose in PET scans is an important topic. Recently, diffusion models have emerged as the new state-of-the-art generative model to generate…

Image and Video Processing · Electrical Eng. & Systems 2023-11-30 Huidong Xie , Weijie Gan , Bo Zhou , Xiongchao Chen , Qiong Liu , Xueqi Guo , Liang Guo , Hongyu An , Ulugbek S. Kamilov , Ge Wang , Chi Liu

Positron Emission Tomography (PET) is an essential technique in many clinical applications that allows for quantitative imaging at the molecular level. This study aims to develop a denoising method using novel dilated convolutional neural…

Medical Physics · Physics 2021-01-27 Karl Spuhler , Mario Serrano-Sosa , Renee Cattell , Christine DeLorenzo , Chuan Huang

Deep learning based PET image reconstruction methods have achieved promising results recently. However, most of these methods follow a supervised learning paradigm, which rely heavily on the availability of high-quality training labels. In…

Image and Video Processing · Electrical Eng. & Systems 2023-03-13 Rui Hu , Yunmei Chen , Kyungsang Kim , Marcio Aloisio Bezerra Cavalcanti Rockenbach , Quanzheng Li , Huafeng Liu

Positron emission tomography (PET) is a cornerstone of modern radiology. The ability to detect cancer and metastases in whole body scans fundamentally changed cancer diagnosis and treatment. One of the main bottlenecks in the clinical…

Computer Vision and Pattern Recognition · Computer Science 2022-04-28 Ida Häggström , C. Ross Schmidtlein , Gabriele Campanella , Thomas J. Fuchs
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