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Pancreatic ductal adenocarcinoma (PDAC) presents a critical global health challenge, and early detection is crucial for improving the 5-year survival rate. Recent medical imaging and computational algorithm advances offer potential…

Image and Video Processing · Electrical Eng. & Systems 2023-11-28 Yu Shi , Hannah Tang , Michael Baine , Michael A. Hollingsworth , Huijing Du , Dandan Zheng , Chi Zhang , Hongfeng Yu

Multi-disease diagnosis using multi-modal data like electronic health records and medical imaging is a critical clinical task. Although existing deep learning methods have achieved initial success in this area, a significant gap persists…

Multimedia · Computer Science 2025-09-22 Yueheng Jiang , Peng Zhang

Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal cancer in which the tumor-vascular involvement greatly affects the resectability and, thus, overall survival of patients. However, current prognostic prediction methods fail to…

Image and Video Processing · Electrical Eng. & Systems 2023-09-14 Hexin Dong , Jiawen Yao , Yuxing Tang , Mingze Yuan , Yingda Xia , Jian Zhou , Hong Lu , Jingren Zhou , Bin Dong , Le Lu , Li Zhang , Zaiyi Liu , Yu Shi , Ling Zhang

Triple-negative breast cancer (TNBC) remains a major clinical challenge due to its aggressive behavior and lack of targeted therapies. Accurate early prediction of response to neoadjuvant chemotherapy (NACT) is essential for guiding…

Quantitative Methods · Quantitative Biology 2025-07-29 Hikmat Khan , Ziyu Su , Huina Zhang , Yihong Wang , Bohan Ning , Shi Wei , Hua Guo , Zaibo Li , Muhammad Khalid Khan Niazi

Recent advances in biological research have seen the emergence of high-throughput technologies with numerous applications that allow the study of biological mechanisms at an unprecedented depth and scale. A large amount of genomic data is…

Machine Learning · Statistics 2020-05-11 Nanwei Wang , Laurent Briollais , Helene Massam

The early detection and nuanced subtype classification of non-small cell lung cancer (NSCLC), a predominant cause of cancer mortality worldwide, is a critical and complex issue. In this paper, we introduce an innovative integration of…

Image and Video Processing · Electrical Eng. & Systems 2024-10-08 Salma Hassan , Hamad Al Hammadi , Ibrahim Mohammed , Muhammad Haris Khan

Accurate survival prediction is essential for personalised cancer treatment. We propose ModalSurv, a multimodal deep survival framework integrating clinical, MRI, histopathology, and RNA-sequencing data via modality-specific projections and…

Machine Learning · Computer Science 2025-12-19 Noorul Wahab , Ethar Alzaid , Jiaqi Lv , Fayyaz Minhas , Adam Shephard , Shan E Ahmed Raza

Generalized Category Discovery (GCD) aims to classify inputs into both known and novel categories, a task crucial for open-world scientific discoveries. However, current GCD methods are limited to unimodal data, overlooking the inherently…

Computer Vision and Pattern Recognition · Computer Science 2024-09-19 Yuchang Su , Renping Zhou , Siyu Huang , Xingjian Li , Tianyang Wang , Ziyue Wang , Min Xu

Breast cancer is a leading cause of cancer-related mortality worldwide, and timely accurate diagnosis is critical to improving survival outcomes. While convolutional neural networks (CNNs) have demonstrated strong performance on…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Aditya Shribhagwan Khandelwal , Mohammad Samar Ansari , Asra Aslam

The use of machine learning (ML) for cancer staging through medical image analysis has gained substantial interest across medical disciplines. When accompanied by the innovative federated learning (FL) framework, ML techniques can further…

Machine Learning · Computer Science 2024-10-10 Kasra Borazjani , Naji Khosravan , Leslie Ying , Seyyedali Hosseinalipour

Breast cancer is a major cause of cancer death among women, emphasising the importance of early detection for improved treatment outcomes and quality of life. Mammography, the primary diagnostic imaging test, poses challenges due to the…

Computer Vision and Pattern Recognition · Computer Science 2023-08-03 Yijun Yang , Shujun Wang , Lihao Liu , Sarah Hickman , Fiona J Gilbert , Carola-Bibiane Schönlieb , Angelica I. Aviles-Rivero

This study proposes a novel approach combining Multimodal Deep Learning with intrinsic eXplainable Artificial Intelligence techniques to predict pathological response in non-small cell lung cancer patients undergoing neoadjuvant therapy.…

Computer Vision and Pattern Recognition · Computer Science 2026-02-16 Alice Natalina Caragliano , Claudia Tacconi , Carlo Greco , Lorenzo Nibid , Edy Ippolito , Michele Fiore , Giuseppe Perrone , Sara Ramella , Paolo Soda , Valerio Guarrasi

Cervical cancer presents a significant global health challenge, necessitating advanced diagnostic and prognostic approaches for effective treatment. This paper investigates the potential of employing multi-modal medical imaging at various…

Medical Physics · Physics 2024-08-27 Haotian Feng , Emi Yoshida , Ke Sheng

Gastric cancer is the fifth most common cancer in the world. At the same time, it is also the fourth most deadly cancer. Early detection of cancer exists as a guide for the treatment of gastric cancer. Nowadays, computer technology has…

Image and Video Processing · Electrical Eng. & Systems 2022-05-26 Weiming Hu , Haoyuan Chen , Wanli Liu , Xiaoyan Li , Hongzan Sun , Xinyu Huang , Marcin Grzegorzek , Chen Li

Genomics, especially multi-omics, has made precision medicine feasible. The completion and publicly accessible multi-omics resource with clinical outcome, such as The Cancer Genome Atlas (TCGA) is a great test bed for developing…

Genomics · Quantitative Biology 2020-08-31 Lana X Garmire

Multi-modal Learning has attracted widespread attention in medical image analysis. Using multi-modal data, whole slide images (WSIs) and clinical information, can improve the performance of deep learning models in the diagnosis of axillary…

Image and Video Processing · Electrical Eng. & Systems 2024-01-04 Shichuan Zhang , Sunyi Zheng , Zhongyi Shui , Honglin Li , Lin Yang

The essence of precision oncology lies in its commitment to tailor targeted treatments and care measures to each patient based on the individual characteristics of the tumor. The inherent heterogeneity of tumors necessitates gathering…

Quantitative Methods · Quantitative Biology 2024-07-01 Huajun Zhou , Fengtao Zhou , Chenyu Zhao , Yingxue Xu , Luyang Luo , Hao Chen

The application of machine learning methods to analyze changes in gene expression patterns has recently emerged as a powerful approach in cancer research, enhancing our understanding of the molecular mechanisms underpinning cancer…

Machine Learning · Computer Science 2024-09-02 Fadi Alharbi , Aleksandar Vakanski , Murtada K. Elbashir , Mohanad Mohammed

Liver cancer is one of the most common cancers worldwide. Due to inconspicuous texture changes of liver tumor, contrast-enhanced computed tomography (CT) imaging is effective for the diagnosis of liver cancer. In this paper, we focus on…

Image and Video Processing · Electrical Eng. & Systems 2021-07-22 Yao Zhang , Jiawei Yang , Jiang Tian , Zhongchao Shi , Cheng Zhong , Yang Zhang , Zhiqiang He

Multimodal deep learning models that fuse whole-slide histopathology images with genomic data have achieved strong discriminative performance for cancer survival prediction, as measured by the concordance index. Yet whether the survival…

Machine Learning · Computer Science 2026-04-07 Sajad Ghawami