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Optical diffraction tomography measures the three-dimensional refractive index map of a specimen and visualizes biochemical phenomena at the nanoscale in a non-destructive manner. One major drawback of optical diffraction tomography is poor…

Image and Video Processing · Electrical Eng. & Systems 2020-09-30 DongHun Ryu , Dongmin Ryu , YoonSeok Baek , Hyungjoo Cho , Geon Kim , Young Seo Kim , Yongki Lee , Yoosik Kim , Jong Chul Ye , Hyun-Seok Min , YongKeun Park

Inverse problems for accelerated MRI typically incorporate domain-specific knowledge about the forward encoding operator in a regularized reconstruction framework. Recently physics-driven deep learning (DL) methods have been proposed to use…

Image and Video Processing · Electrical Eng. & Systems 2020-07-09 Seyed Amir Hossein Hosseini , Burhaneddin Yaman , Steen Moeller , Mingyi Hong , Mehmet Akçakaya

In this paper, we study the nonlinear inverse problem of estimating the spectrum of a system matrix, that drives a finite-dimensional affine dynamical system, from partial observations of a single trajectory data. In the noiseless case, we…

Numerical Analysis · Mathematics 2021-12-22 Jiahui Cheng , Sui Tang

Deep-learning-based methods for different applications have been shown vulnerable to adversarial examples. These examples make deployment of such models in safety-critical tasks questionable. Use of deep neural networks as inverse problem…

Machine Learning · Computer Science 2020-02-28 Ankit Raj , Yoram Bresler , Bo Li

Diffusion models (DMs) have demonstrated remarkable ability to generate diverse and high-quality images by efficiently modeling complex data distributions. They have also been explored as powerful generative priors for signal recovery,…

Machine Learning · Computer Science 2025-05-28 Anqi Tang , Youming Chen , Shuchen Xue , Zhaoqiang Liu

We propose Noisier2Inverse, a correction-free self-supervised deep learning approach for general inverse problems. The proposed method learns a reconstruction function without the need for ground truth samples and is applicable in cases…

Computer Vision and Pattern Recognition · Computer Science 2025-03-30 Nadja Gruber , Johannes Schwab , Markus Haltmeier , Ander Biguri , Clemens Dlaska , Gyeongha Hwang

In this paper, we investigate adaptive nonlinear regression and introduce tree based piecewise linear regression algorithms that are highly efficient and provide significantly improved performance with guaranteed upper bounds in an…

Machine Learning · Computer Science 2013-12-30 N. Denizcan Vanli , Suleyman S. Kozat

Bayesian filtering deals with computing the posterior distribution of the state of a stochastic dynamic system given noisy observations. In this paper, motivated by applications in counter-adversarial systems, we consider the following…

Systems and Control · Electrical Eng. & Systems 2020-10-28 Robert Mattila , Cristian R. Rojas , Vikram Krishnamurthy , Bo Wahlberg

Multi-segment reconstruction (MSR) problem consists of recovering a signal from noisy segments with unknown positions of the observation windows. One example arises in DNA sequence assembly, which is typically solved by matching short reads…

Signal Processing · Electrical Eng. & Systems 2018-02-27 Mona Zehni , Minh N. Do , Zhizhen Zhao

Recent advances have established the identifiability of a directed acyclic graph (DAG) under additive noise models (ANMs), spurring the development of various causal discovery methods. However, most existing methods make restrictive model…

Machine Learning · Statistics 2026-04-24 Stella Huang , Qing Zhou

In distributed detection, there does not exist an automatic way of generating optimal decision strategies for non-affine decision functions. Consequently, in a detection problem based on a non-affine decision function, establishing…

Information Theory · Computer Science 2024-08-20 Earnest Akofor

The aim of this paper is to put the problem of vibroacoustic imaging into the mathematical framework of inverse problems (more precisely, coefficient identification in PDEs) and regularization. We present a model in frequency domain, prove…

Analysis of PDEs · Mathematics 2021-09-07 Barbara Kaltenbacher

The use of differential equations (ODE) is one of the most promising approaches to network inference. The success of ODE-based approaches has, however, been limited, due to the difficulty in estimating parameters and by their lack of…

Molecular Networks · Quantitative Biology 2017-06-09 Yue Deng , Hector Zenil , Jesper Tégner , Narsis A. Kiani

Generating protein sequences that fold into a intended 3D structure is a fundamental step in de novo protein design. De facto methods utilize autoregressive generation, but this eschews higher order interactions that could be exploited to…

Biomolecules · Quantitative Biology 2023-12-06 John J. Yang , Jason Yim , Regina Barzilay , Tommi Jaakkola

Partial differential equation (PDE) models are widely used in engineering and natural sciences to describe spatio-temporal processes. The parameters of the considered processes are often unknown and have to be estimated from experimental…

Numerical Analysis · Mathematics 2016-12-21 Romana Boiger , Jan Hasenauer , Sabrina Hross , Barbara Kaltenbacher

This paper is concerned with the development, analysis and numerical realization of a novel variational model for the regularization of inverse problems in imaging. The proposed model is inspired by the architecture of generative…

Optimization and Control · Mathematics 2021-11-10 Andreas Habring , Martin Holler

Gene regulatory networks are collections of genes that interact with one other and with other substances in the cell. By measuring gene expression over time using high-throughput technologies, it may be possible to reverse engineer, or…

Applications · Statistics 2011-09-08 Andrea Rau , Florence Jaffrézic , Jean-Louis Foulley , R. W. Doerge

Recent work has focused on data-driven learning of the evolution of unknown systems via deep neural networks (DNNs), with the goal of conducting long term prediction of the dynamics of the unknown system. In many real-world applications,…

Machine Learning · Computer Science 2022-06-07 Victor Churchill , Dongbin Xiu

We generalize a stochastic model of DNA replication to the case where replication-origin-initiation rates vary locally along the genome and with time. Using this generalized model, we address the inverse problem of inferring initiation…

Quantitative Methods · Quantitative Biology 2015-04-02 A. Baker , J. Bechhoefer

DNA has immense potential as an emerging data storage medium. The principle of DNA storage is the conversion and flow of digital information between binary code stream, quaternary base, and actual DNA fragments. This process will inevitably…

Information Retrieval · Computer Science 2022-10-21 Yun Qin , Fei Zhu , Bo Xi