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Large multimodal models (LMMs) have demonstrated significant potential in providing innovative solutions for various biomedical tasks, including pathology analysis, radiology report generation, and biomedical assistance. However, the…

Machine Learning · Computer Science 2025-12-30 Dong Xue , Ziyao Shao , Zhaoyang Duan , Fangzhou Liu , Bing Li , Zhongheng Zhang

Large Language Models (LLMs) represent a class of deep learning models adept at understanding natural language and generating coherent responses to various prompts or queries. These models far exceed the complexity of conventional neural…

Machine Learning · Computer Science 2024-12-05 Minghao Shao , Abdul Basit , Ramesh Karri , Muhammad Shafique

Vision-language models (VLMs) exhibit strong zero-shot generalization on natural images and show early promise in interpretable medical image analysis. However, existing benchmarks do not systematically evaluate whether these models truly…

Computer Vision and Pattern Recognition · Computer Science 2025-06-02 Tianhong Zhou , Yin Xu , Yingtao Zhu , Chuxi Xiao , Haiyang Bian , Lei Wei , Xuegong Zhang

Current vision-language models (VLMs) in medicine are primarily designed for categorical question answering (e.g., "Is this normal or abnormal?") or qualitative descriptive tasks. However, clinical decision-making often relies on…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Yongcheng Yao , Yongshuo Zong , Raman Dutt , Yongxin Yang , Sotirios A Tsaftaris , Timothy Hospedales

Multimodal large language models (MLLMs) have demonstrated promise on publicly available dermatology benchmarks. However, benchmark performance may not generalize to real-world dermatologic decision-making. To quantify this…

Computer Vision and Pattern Recognition · Computer Science 2026-05-07 Roy Jiang , Hyunjae Kim , Zhenyue Qin , Morten Lee , Margaret MacGibeny , Ailish Hanly , Angela Sadlowski , Shanin Chowdhury , Xuguang Ai , Jeffrey Gehlhausen , Qingyu Chen

Continual learning is essential for medical image classification systems to adapt to dynamically evolving clinical environments. The integration of multimodal information can significantly enhance continual learning of image classes.…

Computer Vision and Pattern Recognition · Computer Science 2025-08-06 Jiantao Tan , Peixian Ma , Kanghao Chen , Zhiming Dai , Ruixuan Wang

Multimodal large language models have advanced rapidly, but their adoption in medicine is constrained by limited domain coverage, imperfect modality alignment, and insufficient grounded reasoning. We introduce MedMO, a medical multimodal…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Ankan Deria , Komal Kumar , Adinath Madhavrao Dukre , Eran Segal , Salman Khan , Imran Razzak

Recent developments in Multimodal Large Language Models (MLLMs) have significantly improved Vision-Language (VL) reasoning in 2D domains. However, extending these capabilities to 3D scene understanding remains a major challenge. Existing 3D…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Haijier Chen , Bo Xu , Shoujian Zhang , Haoze Liu , Jiaxuan Lin , Jingrong Wang

In the real world, a molecule is a 3D geometric structure. Compared to 1D SMILES sequences and 2D molecular graphs, 3D molecules represent the most informative molecular modality. Despite the rapid progress of autoregressive-based language…

Computational Engineering, Finance, and Science · Computer Science 2025-08-15 Lei Jiang , Shuzhou Sun , Biqing Qi , Yuchen Fu , Xiaohua Xu , Yuqiang Li , Dongzhan Zhou , Tianfan Fu

Recent advances in Large Multimodal Models (LMM) have made it possible for various applications in human-machine interactions. However, developing LMMs that can comprehend, reason, and plan in complex and diverse 3D environments remains a…

Computer Vision and Pattern Recognition · Computer Science 2023-12-01 Sijin Chen , Xin Chen , Chi Zhang , Mingsheng Li , Gang Yu , Hao Fei , Hongyuan Zhu , Jiayuan Fan , Tao Chen

Agentic AI systems have gained significant attention for their ability to autonomously perform complex tasks. However, their reliance on well-prepared tools limits their applicability in the medical domain, which requires to train…

Computer Vision and Pattern Recognition · Computer Science 2025-02-28 Jinghao Feng , Qiaoyu Zheng , Chaoyi Wu , Ziheng Zhao , Ya Zhang , Yanfeng Wang , Weidi Xie

This paper proposes one of the first clinical applications of multimodal large language models (LLMs) as an assistant for radiologists to check errors in their reports. We created an evaluation dataset from real-world radiology datasets…

Computation and Language · Computer Science 2024-03-05 Jinge Wu , Yunsoo Kim , Eva C. Keller , Jamie Chow , Adam P. Levine , Nikolas Pontikos , Zina Ibrahim , Paul Taylor , Michelle C. Williams , Honghan Wu

The adoption of large language models (LLMs) to assist clinicians has attracted remarkable attention. Existing works mainly adopt the close-ended question-answering (QA) task with answer options for evaluation. However, many clinical…

Large Language Models (LLMs) have demonstrated impressive capabilities across various specialist domains and have been integrated into high-stakes areas such as medicine. However, as existing medical-related benchmarks rarely stress-test…

Computation and Language · Computer Science 2026-03-26 Lin Yang , Yuancheng Yang , Xu Wang , Changkun Liu , Haihua Yang

Radiologic diagnostic errors-under-reading errors, inattentional blindness, and communication failures-remain prevalent in clinical practice. These issues often stem from missed localized abnormalities, limited global context, and…

Computer Vision and Pattern Recognition · Computer Science 2025-09-05 Yuheng Li , Yenho Chen , Yuxiang Lai , Jike Zhong , Vanessa Wildman , Xiaofeng Yang

Vision-Language Models (VLMs) trained via contrastive learning have achieved notable success in natural image tasks. However, their application in the medical domain remains limited due to the scarcity of openly accessible, large-scale…

Computer Vision and Pattern Recognition · Computer Science 2024-12-16 Muhammad Uzair Khattak , Shahina Kunhimon , Muzammal Naseer , Salman Khan , Fahad Shahbaz Khan

This study introduces an evaluation framework for multimodal models in medical imaging diagnostics. We developed a pipeline incorporating data preprocessing, model inference, and preference-based evaluation, expanding an initial set of 500…

Image and Video Processing · Electrical Eng. & Systems 2024-12-10 Cailian Ruan , Chengyue Huang , Yahe Yang

Medical image-language pre-training aims to align medical images with clinically relevant text to improve model performance on various downstream tasks. However, existing models often struggle with the variability and ambiguity inherent in…

Computer Vision and Pattern Recognition · Computer Science 2025-07-30 Shreyank N Gowda , Ruichi Zhang , Xiao Gu , Ying Weng , Lu Yang

The recent success of Large Language Models (LLMs) has had a significant impact on the healthcare field, providing patients with medical advice, diagnostic information, and more. However, due to a lack of professional medical knowledge,…

Computation and Language · Computer Science 2024-06-27 Wenya Xie , Qingying Xiao , Yu Zheng , Xidong Wang , Junying Chen , Ke Ji , Anningzhe Gao , Xiang Wan , Feng Jiang , Benyou Wang

Humans excel at performing complex tasks by leveraging long-term memory across temporal and spatial experiences. In contrast, current Large Language Models (LLMs) struggle to effectively plan and act in dynamic, multi-room 3D environments.…

Computer Vision and Pattern Recognition · Computer Science 2025-12-18 Wenbo Hu , Yining Hong , Yanjun Wang , Leison Gao , Zibu Wei , Xingcheng Yao , Nanyun Peng , Yonatan Bitton , Idan Szpektor , Kai-Wei Chang
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