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Conventional computed tomography (CT) lacks the ability to capture dynamic, weight-bearing joint motion. Functional evaluation, particularly after surgical intervention, requires four-dimensional (4D) imaging, but current methods are…

Computer Vision and Pattern Recognition · Computer Science 2025-08-25 Hao Tang , Rongxi Yi , Lei Li , Kaiyi Cao , Jiapeng Zhao , Yihan Xiao , Minghai Shi , Peng Yuan , Yan Xi , Hui Tang , Wei Li , Zhan Wu , Yixin Zhou

The scarcity of publicly available medical imaging data limits the development of effective AI models. This work proposes a memory-efficient patch-wise denoising diffusion probabilistic model (DDPM) for generating synthetic medical images,…

Image and Video Processing · Electrical Eng. & Systems 2024-10-17 Kathrin Khadra , Utku Türkbey

Understanding the structure of the heart at the microscopic scale of cardiomyocytes and their aggregates provides new insights into the mechanisms of heart disease and enables the investigation of effective therapeutics. Diffusion Tensor…

Stereotactic Arrhythmia Radiotherapy (STAR) treats ventricular tachycardia (VT) but requires internal target volume (ITV) expansions to compensate for cardiorespiratory motion. Current clinical r4DCT imaging methods are limited, and the…

Medical Physics · Physics 2025-11-24 Yuhao Wang , Yao Hao , Hongyu An , H Michael Gach , Clifford Robinson , Phillip S Cuculich , Deshan Yang

Background: Voxel-based analysis (VBA) for population level radiotherapy (RT) outcomes modeling requires topology preserving inter-patient deformable image registration (DIR) that preserves tumors on moving images while avoiding unrealistic…

Image and Video Processing · Electrical Eng. & Systems 2024-11-28 Jue Jiang , Chloe Min Seo Choi , Maria Thor , Joseph O. Deasy , Harini Veeraraghavan

Medical ultrasound provides images which are the spatial map of the tissue echogenicity. Unfortunately, an ultrasound image is a low-quality version of the expected Tissue Reflectivity Function (TRF) mainly due to the non-ideal Point Spread…

Image and Video Processing · Electrical Eng. & Systems 2021-09-28 Sobhan Goudarzi , Hassan Rivaz

Background: Cone-beam computed tomography (CBCT) scans, performed fractionally (e.g., daily or weekly), are widely utilized for patient alignment in the image-guided radiotherapy (IGRT) process, thereby making it a potential imaging…

We propose an unsupervised deep learning algorithm for the motion-compensated reconstruction of 5D cardiac MRI data from 3D radial acquisitions. Ungated free-breathing 5D MRI simplifies the scan planning, improves patient comfort, and…

Image and Video Processing · Electrical Eng. & Systems 2023-09-12 Joseph Kettelkamp , Ludovica Romanin , Davide Piccini , Sarv Priya , Mathews Jacob

In vivo cardiac diffusion tensor imaging (cDTI) is a promising Magnetic Resonance Imaging (MRI) technique for evaluating the micro-structure of myocardial tissue in the living heart, providing insights into cardiac function and enabling the…

Computed tomography (CT) is widely used in screening, diagnosis, and image-guided therapy for both clinical and research purposes. Since CT involves ionizing radiation, an overarching thrust of related technical research is development of…

Image and Video Processing · Electrical Eng. & Systems 2019-06-25 Chenyu You , Guang Li , Yi Zhang , Xiaoliu Zhang , Hongming Shan , Shenghong Ju , Zhen Zhao , Zhuiyang Zhang , Wenxiang Cong , Michael W. Vannier , Punam K. Saha , Ge Wang

In lung radiotherapy, the primary objective is to optimize treatment outcomes by minimizing exposure to healthy tissues while delivering the prescribed dose to the target volume. The challenge lies in accounting for lung tissue motion due…

Medical Physics · Physics 2024-11-26 Frederic Madesta , Lukas Wimmert , Tobias Gauer , René Werner , Thilo Sentker

In medical imaging, the diffusion models have shown great potential for synthetic image generation tasks. However, these approaches often lack the interpretable connections between the generated and real images and can create anatomically…

Image and Video Processing · Electrical Eng. & Systems 2026-02-12 Jian-Qing Zheng , Yuanhan Mo , Yang Sun , Jiahua Li , Fuping Wu , Ziyang Wang , Tonia Vincent , Bartłomiej W. Papież

Transcranial focused ultrasound (tFUS) is a therapeutic ultrasound method that focuses sound through the skull to a small region noninvasively and often under MRI guidance. CT imaging is used to estimate the acoustic properties that vary…

Image and Video Processing · Electrical Eng. & Systems 2022-10-27 Han Liu , Michelle K. Sigona , Thomas J. Manuel , Li Min Chen , Benoit M. Dawant , Charles F. Caskey

In recent years, deep-learning-based image processing has emerged as a valuable tool for medical imaging owing to its high performance. However, the quality of deep-learning-based methods heavily relies on the amount of training data; the…

Computer Vision and Pattern Recognition · Computer Science 2022-10-12 Sho Ozaki , Shizuo Kaji , Kanabu Nawa , Toshikazu Imae , Atsushi Aoki , Takahiro Nakamoto , Takeshi Ohta , Yuki Nozawa , Hideomi Yamashita , Akihiro Haga , Keiichi Nakagawa

Respiratory motion can cause strong blurring artifacts in the reconstructed image during MR acquisition. These artifacts become more prominent when use in the presence of undersampled data. Recently, compressed sensing (CS) is developed as…

Image and Video Processing · Electrical Eng. & Systems 2019-04-10 Abdul Haseeb Ahmed , Ijaz M. Qureshi , Jawad Ali Shah , Hammad Omer

Weakly supervised disease classification of CT imaging suffers from poor localization owing to case-level annotations, where even a positive scan can hold hundreds to thousands of negative slices along multiple planes. Furthermore, although…

Computer Vision and Pattern Recognition · Computer Science 2020-11-03 Anindo Saha , Fakrul I. Tushar , Khrystyna Faryna , Vincent M. D'Anniballe , Rui Hou , Maciej A. Mazurowski , Geoffrey D. Rubin , Joseph Y. Lo

Respiration-correlated CBCT, commonly called 4DCBCT, provide respiratory phase-resolved CBCT images. In many clinical applications, it is more preferable to reconstruct true 4DCBCT with the 4th dimension being time, i.e., each CBCT image is…

Medical Physics · Physics 2012-04-17 Jian-Feng Cai , Xun Jia , Hao Gao , Steve B. Jiang , Zuowei Shen , Hongkai Zhao

Although mechanical ventilation is a lifesaving intervention in the ICU, it has harmful side-effects, such as barotrauma and volutrauma. These harms can occur due to asynchronies. Asynchronies are defined as a mismatch between the…

Computer Vision and Pattern Recognition · Computer Science 2022-02-11 A. van Diepen , T. H. G. F. Bakkes , A. J. R. De Bie , S. Turco , R. A. Bouwman , P. H. Woerlee , M. Mischi

In cardiac magnetic resonance (CMR) imaging, a 3D high-resolution segmentation of the heart is essential for detailed description of its anatomical structures. However, due to the limit of acquisition duration and respiratory/cardiac…

Image and Video Processing · Electrical Eng. & Systems 2021-07-09 Shuo Wang , Chen Qin , Nicolo Savioli , Chen Chen , Declan O'Regan , Stuart Cook , Yike Guo , Daniel Rueckert , Wenjia Bai

While remarkable advances have been made in Computed Tomography (CT), most of the existing efforts focus on imaging enhancement while reducing radiation dose. How to harmonize CT image data captured using different scanners is vital in…

Image and Video Processing · Electrical Eng. & Systems 2021-10-20 Md Selim , Jie Zhang , Baowei Fei , Guo-Qiang Zhang , Gary Yeeming Ge , Jin Chen