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Fluorescence microscopy images contain several channels, each indicating a marker staining the sample. Since many different marker combinations are utilized in practice, it has been challenging to apply deep learning based segmentation…

Computer Vision and Pattern Recognition · Computer Science 2021-01-28 Alvaro Gomariz , Raphael Egli , Tiziano Portenier , César Nombela-Arrieta , Orcun Goksel

Systematic failures of computer vision models on subsets with coherent visual patterns, known as error slices, pose a critical challenge for robust model evaluation. Existing slice discovery methods are primarily developed for image…

Computer Vision and Pattern Recognition · Computer Science 2026-01-01 Wei Zhang , Chaoqun Wang , Zixuan Guan , Sam Kao , Pengfei Zhao , Peng Wu , Sifeng He

In this paper, we consider the problem of automatically segmenting neuronal cells in dual-color confocal microscopy images. This problem is a key task in various quantitative analysis applications in neuroscience, such as tracing cell…

Computer Vision and Pattern Recognition · Computer Science 2017-06-01 Jianxu Chen , Sreya Banerjee , Abhinav Grama , Walter J. Scheirer , Danny Z. Chen

The throughput of electron microscopes has increased significantly in recent years, enabling detailed analysis of cell morphology and ultrastructure. Analysis of neural circuits at single-synapse resolution remains the flagship target of…

Computer Vision and Pattern Recognition · Computer Science 2019-08-07 Constantin Pape , Alex Matskevych , Adrian Wolny , Julian Hennies , Giula Mizzon , Marion Louveaux , Jacob Musser , Alexis Maizel , Detlev Arendt , Anna Kreshuk

Diseases such as diabetic retinopathy and age-related macular degeneration pose a significant risk to vision, highlighting the importance of precise segmentation of retinal vessels for the tracking and diagnosis of progression. However,…

Image and Video Processing · Electrical Eng. & Systems 2023-09-08 Tariq M. Khan , Muhammad Arsalan , Shahzaib Iqbal , Imran Razzak , Erik Meijering

Recent advances in deep learning (DL) have significantly impacted motor imagery (MI)-based brain-computer interface (BCI) systems, enhancing the decoding of electroencephalography (EEG) signals. However, most studies struggle to identify…

Machine Learning · Computer Science 2024-09-09 Phairot Autthasan , Rattanaphon Chaisaen , Huy Phan , Maarten De Vos , Theerawit Wilaiprasitporn

Instance segmentation with neural networks is an essential task in environment perception. In many works, it has been observed that neural networks can predict false positive instances with high confidence values and true positives with low…

Computer Vision and Pattern Recognition · Computer Science 2026-01-13 Kira Maag , Matthias Rottmann , Serin Varghese , Fabian Hueger , Peter Schlicht , Hanno Gottschalk

We present a new instance segmentation approach tailored to biological images, where instances may correspond to individual cells, organisms or plant parts. Unlike instance segmentation for user photographs or road scenes, in biological…

Computer Vision and Pattern Recognition · Computer Science 2020-04-24 Victor Kulikov , Victor Lempitsky

Artificially generated induced pluripotent stem cells (iPSCs) from somatic cells play an important role for disease modeling and drug screening of neurodegenerative diseases. Astrocytes differentiated from iPSCs are important targets to…

Image and Video Processing · Electrical Eng. & Systems 2024-02-07 Haoran Li , Jiahua Shi , Huaming Chen , Bo Du , Simon Maksour , Gabrielle Phillips , Mirella Dottori , Jun Shen

Nucleus instance segmentation from histopathology images suffers from the extremely laborious and expert-dependent annotation of nucleus instances. As a promising solution to this task, annotation-efficient deep learning paradigms have…

Computer Vision and Pattern Recognition · Computer Science 2024-02-29 Yu Ming , Zihao Wu , Jie Yang , Danyi Li , Yuan Gao , Changxin Gao , Gui-Song Xia , Yuanqing Li , Li Liang , Jin-Gang Yu

Fluorescence microscopy has become a widely used tool for studying various biological structures of in vivo tissue or cells. However, quantitative analysis of these biological structures remains a challenge due to their complexity which is…

Computer Vision and Pattern Recognition · Computer Science 2019-04-16 Soonam Lee , Chichen Fu , Paul Salama , Kenneth W. Dunn , Edward J. Delp

Real-time semantic segmentation, which can be visually understood as the pixel-level classification task on the input image, currently has broad application prospects, especially in the fast-developing fields of autonomous driving and drone…

Computer Vision and Pattern Recognition · Computer Science 2022-03-08 Guangwei Gao , Guoan Xu , Juncheng Li , Yi Yu , Huimin Lu , Jian Yang

Retinal blood vessel segmentation can extract clinically relevant information from fundus images. As manual tracing is cumbersome, algorithms based on Convolution Neural Networks have been developed. Such studies have used small publicly…

Image and Video Processing · Electrical Eng. & Systems 2024-06-24 Jeremiah Fadugba , Patrick Köhler , Lisa Koch , Petru Manescu , Philipp Berens

Segmentation is essential for medical image analysis to identify and localize diseases, monitor morphological changes, and extract discriminative features for further diagnosis. Skin cancer is one of the most common types of cancer…

Image and Video Processing · Electrical Eng. & Systems 2022-09-02 Hritam Basak , Rohit Kundu , Ram Sarkar

This work proposed a novel learning objective to train a deep neural network to perform end-to-end image pixel clustering. We applied the approach to instance segmentation, which is at the intersection of image semantic segmentation and…

Computer Vision and Pattern Recognition · Computer Science 2018-03-20 Yen-Chang Hsu , Zheng Xu , Zsolt Kira , Jiawei Huang

The information content of atomic resolution scanning transmission electron microscopy (STEM) images can often be reduced to a handful of parameters describing each atomic column, chief amongst which is the column position. Neural networks…

Materials Science · Physics 2023-02-22 Jingrui Wei , Ben Blaiszik , Aristana Scourtas , Dane Morgan , Paul M. Voyles

Cell instance segmentation in fluorescence microscopy images is becoming essential for cancer dynamics and prognosis. Data extracted from cancer dynamics allows to understand and accurately model different metabolic processes such as…

Automatic segmentation of neuronal topology is critical for handling large scale neuroimaging data, as it can greatly accelerate neuron annotation and analysis. However, the intricate morphology of neuronal branches and the occlusions among…

Image and Video Processing · Electrical Eng. & Systems 2025-08-01 Huayu Fu , Jiamin Li , Haozhi Qu , Xiaolin Hu , Zengcai Guo

Segmentation and quantification of white matter hyperintensities (WMHs) are of great importance in studying and understanding various neurological and geriatric disorders. Although automatic methods have been proposed for WMH segmentation…

Computer Vision and Pattern Recognition · Computer Science 2018-03-20 Dakai Jin , Ziyue Xu , Adam P. Harrison , Daniel J. Mollura

Advances in fluorescence microscopy enable acquisition of 3D image volumes with better image quality and deeper penetration into tissue. Segmentation is a required step to characterize and analyze biological structures in the images and…

Computer Vision and Pattern Recognition · Computer Science 2019-04-16 Chichen Fu , Soonam Lee , David Joon Ho , Shuo Han , Paul Salama , Kenneth W. Dunn , Edward J. Delp