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Generating molecules with desired chemical properties presents a critical challenge in fields such as chemical synthesis and drug discovery. Recent advancements in artificial intelligence (AI) and deep learning have significantly…

Machine Learning · Computer Science 2025-09-25 Chen Li , Huidong Tang , Ye Zhu , Yoshihiro Yamanishi

Deep generative models, such as generative adversarial networks (GANs), are pivotal in discovering novel drug-like candidates via de novo molecular generation. However, traditional character-wise tokenizers often struggle with identifying…

Machine Learning · Computer Science 2024-10-01 Huidong Tang , Chen Li , Yasuhiko Morimoto

Generative adversarial networks (GANs) have emerged as a powerful tool for generating high-fidelity data. However, the main bottleneck of existing approaches is the lack of supervision on the generator training, which often results in…

Computer Vision and Pattern Recognition · Computer Science 2025-02-18 Baoren Xiao , Hao Ni , Weixin Yang

We propose a framework of generative adversarial networks with multiple discriminators, which collaborate to represent a real dataset more effectively. Our approach facilitates learning a generator consistent with the underlying data…

Machine Learning · Computer Science 2024-04-04 Jinyoung Choi , Bohyung Han

The aim of the inverse chemical design is to develop new molecules with given optimized molecular properties or objectives. Recently, generative deep learning (DL) networks are considered as the state-of-the-art in inverse chemical design…

Machine Learning · Computer Science 2019-10-10 Haoran Wei , Mariefel Olarte , Garrett B. Goh

Generative adversarial networks (GANs) are a recently proposed class of generative models in which a generator is trained to optimize a cost function that is being simultaneously learned by a discriminator. While the idea of learning cost…

Machine Learning · Computer Science 2016-11-28 Chelsea Finn , Paul Christiano , Pieter Abbeel , Sergey Levine

The utility of machine learning (ML) techniques in materials science has accelerated materials design and discovery. However, the accuracy of ML models - particularly deep neural networks - heavily relies on the quality and quantity of the…

Materials Science · Physics 2023-10-25 Marzie Ghorbani , Zhipeng Li , Nick Birbilis

As a new way of training generative models, Generative Adversarial Nets (GAN) that uses a discriminative model to guide the training of the generative model has enjoyed considerable success in generating real-valued data. However, it has…

Machine Learning · Computer Science 2017-08-28 Lantao Yu , Weinan Zhang , Jun Wang , Yong Yu

In unsupervised data generation tasks, besides the generation of a sample based on previous observations, one would often like to give hints to the model in order to bias the generation towards desirable metrics. We propose a method that…

Generative Adversarial Networks (GANs), as a framework for estimating generative models via an adversarial process, have attracted huge attention and have proven to be powerful in a variety of tasks. However, training GANs is well known for…

Machine Learning · Computer Science 2017-11-09 Zi-Yi Dou

One of the most significant challenges in statistical signal processing and machine learning is how to obtain a generative model that can produce samples of large-scale data distribution, such as images and speeches. Generative Adversarial…

Computer Vision and Pattern Recognition · Computer Science 2020-05-28 Pegah Salehi , Abdolah Chalechale , Maryam Taghizadeh

A major challenge in materials design is how to efficiently search the vast chemical design space to find the materials with desired properties. One effective strategy is to develop sampling algorithms that can exploit both explicit…

Machine Learning · Computer Science 2020-06-30 Yabo Dan , Yong Zhao , Xiang Li , Shaobo Li , Ming Hu , Jianjun Hu

Generative adversarial networks (GANs) provide an algorithmic framework for constructing generative models with several appealing properties: they do not require a likelihood function to be specified, only a generating procedure; they…

Machine Learning · Statistics 2017-02-28 Shakir Mohamed , Balaji Lakshminarayanan

Botnet detectors based on machine learning are potential targets for adversarial evasion attacks. Several research works employ adversarial training with samples generated from generative adversarial nets (GANs) to make the botnet detectors…

Cryptography and Security · Computer Science 2022-10-07 Rizwan Hamid Randhawa , Nauman Aslam , Mohammad Alauthman , Muhammad Khalid , Husnain Rafiq

Machine learning has been used to detect new malware in recent years, while malware authors have strong motivation to attack such algorithms. Malware authors usually have no access to the detailed structures and parameters of the machine…

Machine Learning · Computer Science 2017-02-21 Weiwei Hu , Ying Tan

We propose a new approach to train the Generative Adversarial Nets (GANs) with a mixture of generators to overcome the mode collapsing problem. The main intuition is to employ multiple generators, instead of using a single one as in the…

Machine Learning · Computer Science 2017-10-31 Quan Hoang , Tu Dinh Nguyen , Trung Le , Dinh Phung

Generative Adversarial Networks (GANs) have shown immense potential in fields such as text and image generation. Only very recently attempts to exploit GANs to statistical-mechanics models have been reported. Here we quantitatively test…

Statistical Mechanics · Physics 2024-05-07 Daniele Lanzoni , Olivier Pierre-Louis , Francesco Montalenti

Navigating the vast chemical space of molecular structures to design novel drug molecules with desired target properties remains a central challenge in drug discovery. Recent advances in generative models offer promising solutions. This…

Recent advances in deep learning have accelerated its use in various applications, such as cellular image analysis and molecular discovery. In molecular discovery, a generative adversarial network (GAN), which comprises a discriminator to…

Machine Learning · Computer Science 2023-04-13 Daniel Manu , Jingjing Yao , Wuji Liu , Xiang Sun

Semi-supervision in Machine Learning can be used in searches for new physics where the signal plus background regions are not labelled. This strongly reduces model dependency in the search for signals Beyond the Standard Model. This…

High Energy Physics - Phenomenology · Physics 2022-02-04 Thabang Lebese , Xifeng Ruan
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