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Breast cancer is one of the most common cancers among women worldwide, and its accurate and timely diagnosis plays a critical role in improving treatment outcomes. This thesis presents an innovative framework for detecting malignant masses…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Ehsan Sadeghi Pour , Mahdi Esmaeili , Morteza Romoozi

This paper proposes an efficient system for classifying cervical cancer cells using pre-trained convolutional neural networks (CNNs). We first fine-tune five pre-trained CNNs and minimize the overall cost of misclassification by…

Computer Vision and Pattern Recognition · Computer Science 2024-02-27 Ashfiqun Mustari , Rushmia Ahmed , Afsara Tasnim , Jakia Sultana Juthi , G M Shahariar

As machine learning (ML) models and datasets increase in complexity, the demand for methods that enhance explainability and interpretability becomes paramount. Prototypes, by encapsulating essential characteristics within data, offer…

Machine Learning · Computer Science 2024-08-20 Orfeas Menis-Mastromichalakis , Giorgos Filandrianos , Jason Liartis , Edmund Dervakos , Giorgos Stamou

In the context of image classification, Concept Bottleneck Models (CBMs) first embed images into a set of human-understandable concepts, followed by an intrinsically interpretable classifier that predicts labels based on these intermediate…

Computer Vision and Pattern Recognition · Computer Science 2025-10-02 Haifei Zhang , Patrick Barry , Eduardo Brandao

The emergence of deep learning networks raises a need for explainable AI so that users and domain experts can be confident applying them to high-risk decisions. In this paper, we leverage data from the latent space induced by deep learning…

Machine Learning · Computer Science 2019-09-10 Alan H. Gee , Diego Garcia-Olano , Joydeep Ghosh , David Paydarfar

Pretrained transformer-based Language Models (LMs) are well-known for their ability to achieve significant improvement on NLP tasks, but their black-box nature, which leads to a lack of interpretability, has been a major concern. My…

Computation and Language · Computer Science 2024-12-06 Ximing Wen

Purpose: To determine whether deep learning models can distinguish between breast cancer molecular subtypes based on dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI). Materials and methods: In this institutional review…

Computer Vision and Pattern Recognition · Computer Science 2017-12-01 Zhe Zhu , Ehab Albadawy , Ashirbani Saha , Jun Zhang , Michael R. Harowicz , Maciej A. Mazurowski

The application of deep learning in medical imaging has significantly advanced diagnostic capabilities, enhancing both accuracy and efficiency. Despite these benefits, the lack of transparency in these AI models, often termed "black boxes,"…

Computer Vision and Pattern Recognition · Computer Science 2024-09-23 Eleonora Beatrice Rossi , Eleonora Lopez , Danilo Comminiello

Survival analysis is a statistical framework for modeling time-to-event data, particularly valuable in healthcare for predicting outcomes like patient discharge or recurrence. This study implements and compares several survival models -…

With the advances in artificial intelligence (AI), data-driven algorithms are becoming increasingly popular in the medical domain. However, due to the nonlinear and complex behavior of many of these algorithms, decision-making by such…

Quantitative Methods · Quantitative Biology 2024-07-18 Amirehsan Ghasemi , Soheil Hashtarkhani , David L Schwartz , Arash Shaban-Nejad

Deep learning-based electrocardiogram (ECG) classification has shown impressive performance but clinical adoption has been slowed by the lack of transparent and faithful explanations. Post hoc methods such as saliency maps may fail to…

The use of wearables in medicine and wellness, enabled by AI-based models, offers tremendous potential for real-time monitoring and interpretable event detection. Explainable AI (XAI) is required to assess what models have learned and build…

Signal Processing · Electrical Eng. & Systems 2026-03-16 Maurice Kuschel , Solveig Vieluf , Claus Reinsberger , Tobias Loddenkemper , Tanuj Hasija

Recent years have witnessed the widespread adoption of reinforcement learning (RL), from solving real-time games to fine-tuning large language models using human preference data significantly improving alignment with user expectations.…

Machine Learning · Computer Science 2026-04-01 Bodla Krishna Vamshi , Haizhao Yang

We present a deformable prototypical part network (Deformable ProtoPNet), an interpretable image classifier that integrates the power of deep learning and the interpretability of case-based reasoning. This model classifies input images by…

Computer Vision and Pattern Recognition · Computer Science 2024-05-06 Jon Donnelly , Alina Jade Barnett , Chaofan Chen

This paper claims that machine learning models deployed in high stakes domains such as medicine must be interpretable, shareable, reproducible and accountable. We argue that these principles should form the foundational design criteria for…

Machine Learning · Computer Science 2025-08-25 Ayyüce Begüm Bektaş , Mithat Gönen

The use of sophisticated machine learning models for critical decision making is faced with a challenge that these models are often applied as a "black-box". This has led to an increased interest in interpretable machine learning, where…

Artificial Intelligence · Computer Science 2020-07-22 Catarina Moreira , Yu-Liang Chou , Mythreyi Velmurugan , Chun Ouyang , Renuka Sindhgatta , Peter Bruza

Concept Bottleneck Models (CBMs) offer interpretable alternatives to black-box predictors by introducing human-relatable concepts before the final output. However, existing CBMs struggle to verify whether predicted concepts correspond to…

Machine Learning · Computer Science 2026-05-15 Yingying Fang , Haijie Xu , Shuang Wu , Mariathasan Anish , Guang Yang

We propose a fast, model agnostic method for finding interpretable counterfactual explanations of classifier predictions by using class prototypes. We show that class prototypes, obtained using either an encoder or through class specific…

Machine Learning · Computer Science 2020-02-19 Arnaud Van Looveren , Janis Klaise

A major obstacle to the integration of deep learning models for chest x-ray interpretation into clinical settings is the lack of understanding of their failure modes. In this work, we first investigate whether there are patient subgroups…

Computer Vision and Pattern Recognition · Computer Science 2021-07-21 Emma Chen , Andy Kim , Rayan Krishnan , Jin Long , Andrew Y. Ng , Pranav Rajpurkar

The lack of explainability is one of the most prominent disadvantages of deep learning applications in omics. This "black box" problem can undermine the credibility and limit the practical implementation of biomedical deep learning models.…

Genomics · Quantitative Biology 2021-08-19 Eloise Withnell , Xiaoyu Zhang , Kai Sun , Yike Guo
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