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Background Predicting overall survival (OS) in non-small cell lung cancer (NSCLC) is essential for clinical decision-making and drug development. While tumor and blood test markers kinetics are intrinsically linked, their joint dynamics and…

Quantitative Methods · Quantitative Biology 2026-01-19 Ruben Taieb , René Bruno , Pascal Chanu , Jin Yan Jin , Sébastien Benzekry

Many existing digital triage systems are questionnaire-based, guiding patients to appropriate care levels based on information (e.g., symptoms, medical history, and urgency) provided by the patients answering questionnaires. Such a system…

Artificial Intelligence · Computer Science 2025-04-17 Sofia Krylova , Fabian Schmidt , Vladimir Vlassov

Electronic health records are an increasingly important resource for understanding the interactions between patient health, environment, and clinical decisions. In this paper we report an empirical study of predictive modeling of several…

Computers and Society · Computer Science 2019-03-29 William La Cava , Christopher Bauer , Jason H. Moore , Sarah A Pendergrass

In observational studies, propensity scores are commonly estimated by maxi- mum likelihood but may fail to balance high-dimensional pre-treatment covariates even after specification search. We introduce a general framework that unifies and…

Methodology · Statistics 2017-03-22 Qingyuan Zhao

Metabolic syndrome (MetS) is a medication condition characterized by abdominal obesity, insulin resistance, hypertension and hyperlipidemia. It increases the risk of majority of chronic diseases, including type 2 diabetes mellitus, and…

Artificial Intelligence · Computer Science 2025-05-14 Yichen Zhao , Yuhua Wang , Xi Cheng , Junhao Fang , Yang Yang

Recent works have shown that deep neural networks can achieve super-human performance in a wide range of image classification tasks in the medical imaging domain. However, these works have primarily focused on classification accuracy,…

Computer Vision and Pattern Recognition · Computer Science 2020-09-10 Gongbo Liang , Yu Zhang , Xiaoqin Wang , Nathan Jacobs

Dry eye disease is a common disorder of the ocular surface, leading patients to seek eye care. Clinical signs and symptoms are currently used to diagnose dry eye disease. Metabolomics, a method for analyzing biological systems, has been…

Computer Vision and Pattern Recognition · Computer Science 2024-08-08 Sajad Amouei Sheshkal , Morten Gundersen , Michael Alexander Riegler , Øygunn Aass Utheim , Kjell Gunnar Gundersen , Hugo Lewi Hammer

Clinical decision support using data mining techniques offers more intelligent way to reduce the decision error in the last few years. However, clinical datasets often suffer from high missingness, which adversely impacts the quality of…

Machine Learning · Computer Science 2020-11-20 Xuetong Wu , Hadi Akbarzadeh Khorshidi , Uwe Aickelin , Zobaida Edib , Michelle Peate

Objective: A digital twin of a patient can be a valuable tool for enhancing clinical tasks such as workflow automation, patient-specific X-ray dose optimization, markerless tracking, positioning, and navigation assistance in image-guided…

Computer Vision and Pattern Recognition · Computer Science 2023-03-10 Karthik Shetty , Annette Birkhold , Srikrishna Jaganathan , Norbert Strobel , Bernhard Egger , Markus Kowarschik , Andreas Maier

The increasing global prevalence of mental disorders, such as depression and PTSD, requires objective and scalable diagnostic tools. Traditional clinical assessments often face limitations in accessibility, objectivity, and consistency.…

Audio and Speech Processing · Electrical Eng. & Systems 2025-04-03 Abdelrahaman A. Hassan , Abdelrahman A. Ali , Aya E. Fouda , Radwa J. Hanafy , Mohammed E. Fouda

Automatic detection of brain neoplasm in Magnetic Resonance Imaging (MRI) is gaining importance in many medical diagnostic applications. This report presents two improvements for brain neoplasm detection in MRI data: an advanced…

Computer Vision and Pattern Recognition · Computer Science 2021-01-26 Nilanjan Sinhababu , Monalisa Sarma , Debasis Samanta

The segmentation of metastatic bone disease (MBD) in whole-body MRI (WB-MRI) is a challenging problem. Due to varying appearances and anatomical locations of lesions, ambiguous boundaries, and severe class imbalance, obtaining reliable…

Image and Video Processing · Electrical Eng. & Systems 2025-06-25 Joris Wuts , Jakub Ceranka , Nicolas Michoux , Frédéric Lecouvet , Jef Vandemeulebroucke

In many nations, diabetes is becoming a significant health problem, and early identification and control are crucial. Using machine learning algorithms to predict diabetes has yielded encouraging results. Using the Pima Indians Diabetes…

Machine Learning · Computer Science 2025-06-13 Mowafaq Salem Alzboon , Mohammad Al-Batah , Muhyeeddin Alqaraleh , Ahmad Abuashour , Ahmad Fuad Bader

The performance of many machine learning models depends on their hyper-parameter settings. Bayesian Optimization has become a successful tool for hyper-parameter optimization of machine learning algorithms, which aims to identify optimal…

Machine Learning · Computer Science 2020-08-04 Lidan Wang , Franck Dernoncourt , Trung Bui

The development of electronic stethoscopes and wearable recording sensors opened the door to the automated analysis of bowel sound (BS) signals. This enables a data-driven analysis of bowel sound patterns, their interrelations, and their…

Sound · Computer Science 2025-02-25 Zahra Mansour , Verena Uslar , Dirk Weyhe , Danilo Hollosi , Nils Strodthoff

Sepsis is a severe condition responsible for many deaths in the United States and worldwide, making accurate prediction of outcomes crucial for timely and effective treatment. Previous studies employing machine learning faced limitations in…

Machine Learning · Computer Science 2025-01-03 Arseniy Shumilov , Yueting Zhu , Negin Ashrafi , Armin Abdollahi , Greg Placencia , Kamiar Alaei , Maryam Pishgar

Obesity is a critical global health issue driven by dietary, physiological, and environmental factors, and is strongly associated with chronic diseases such as diabetes, cardiovascular disorders, and cancer. Machine learning has emerged as…

Machine Learning · Computer Science 2026-05-11 Towhidul Islam , Md Sumon Ali

Bearings are among the most failure-prone components in rotating machinery, and their condition directly impacts overall performance. Therefore, accurately diagnosing bearing faults is essential for ensuring system stability. However,…

Signal Processing · Electrical Eng. & Systems 2025-09-26 Amir Eshaghi Chaleshtori , Abdollah Aghaie

Regularized regression approaches such as the Lasso have been widely adopted for constructing sparse linear models in high-dimensional datasets. A complexity in fitting these models is the tuning of the parameters which control the level of…

Methodology · Statistics 2019-03-12 Ellis Patrick , Samuel Mueller

Student's mental health problems have been explored previously in higher education literature in various contexts including empirical work involving quantitative and qualitative methods. Nevertheless, comparatively few research could be…

Applications · Statistics 2022-03-01 Prathamesh Muzumdar , Ganga Prasad Basyal , Piyush Vyas