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Large language models (LLMs) exhibit remarkable capabilities across diverse tasks, yet aligning them efficiently and effectively with human expectations remains a critical challenge. This thesis advances LLM alignment by introducing novel…

Computation and Language · Computer Science 2025-06-12 Yuxin Jiang

Masked language modeling (MLM) has been widely used for pre-training effective bidirectional representations, but incurs substantial training costs. In this paper, we propose a novel concept-based curriculum masking (CCM) method to…

Computation and Language · Computer Science 2022-12-16 Mingyu Lee , Jun-Hyung Park , Junho Kim , Kang-Min Kim , SangKeun Lee

We aim to present a comprehensive overview of the latest advancements in utilizing Large Language Models (LLMs) within the healthcare sector, emphasizing their transformative impact across various medical domains. LLMs have become pivotal…

Computation and Language · Computer Science 2026-04-07 Ummara Mumtaz , Awais Ahmed , Summaya Mumtaz

The field of natural language processing (NLP) has recently seen a large change towards using pre-trained language models for solving almost any task. Despite showing great improvements in benchmark datasets for various tasks, these models…

Computation and Language · Computer Science 2022-05-24 Lukas Lange , Heike Adel , Jannik Strötgen , Dietrich Klakow

Molecular property prediction is a crucial foundation for drug discovery. In recent years, pre-trained deep learning models have been widely applied to this task. Some approaches that incorporate prior biological domain knowledge into the…

Machine Learning · Computer Science 2024-08-20 Tianyu Zhang , Yuxiang Ren , Chengbin Hou , Hairong Lv , Xuegong Zhang

In Natural Language Processing (NLP), Machine Reading Comprehension (MRC) is the task of answering a question based on a given context. To handle questions in the medical domain, modern language models such as BioBERT, SciBERT and even…

Computation and Language · Computer Science 2024-12-16 Saptarshi Sengupta , Connor Heaton , Suhan Cui , Soumalya Sarkar , Prasenjit Mitra

With the advancement of Large Language Model (LLM) for natural language processing, this paper presents an intriguing finding: a frozen pre-trained LLM layer can process visual tokens for medical image segmentation tasks. Specifically, we…

Computer Vision and Pattern Recognition · Computer Science 2025-06-24 Fenghe Tang , Wenxin Ma , Zhiyang He , Xiaodong Tao , Zihang Jiang , S. Kevin Zhou

Although recent advances in scaling large language models (LLMs) have resulted in improvements on many NLP tasks, it remains unclear whether these models trained primarily with general web text are the right tool in highly specialized,…

Language models (LMs) excel at tasks across diverse domains, yet require substantial computational resources during inference. Compression techniques such as pruning and quantization offer a practical path towards efficient LM deployment,…

Computation and Language · Computer Science 2026-02-26 Miles Williams , George Chrysostomou , Vitor Jeronymo , Nikolaos Aletras

Multimodal Large Language Models advance multimodal representation learning by acquiring transferable semantic embeddings, thereby substantially enhancing performance across a range of vision-language tasks, including cross-modal retrieval,…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Da Li , Yuxiao Luo , Keping Bi , Jiafeng Guo , Wei Yuan , Biao Yang , Yan Wang , Fan Yang , Tingting Gao , Guorui Zhou

Large language models are powerful but costly. We ask whether meta-learning can make the pretraining of small language models not only better but also more interpretable. We integrate first-order MAML with subset-masked LM pretraining,…

Computation and Language · Computer Science 2025-11-10 David Demitri Africa , Yuval Weiss , Paula Buttery , Richard Diehl Martinez

Large pre-trained models have achieved great success in many natural language processing tasks. However, when they are applied in specific domains, these models suffer from domain shift and bring challenges in fine-tuning and online serving…

Computation and Language · Computer Science 2021-06-30 Yunzhi Yao , Shaohan Huang , Wenhui Wang , Li Dong , Furu Wei

Large language models (LLMs) have revolutionized natural language processing by achieving state-of-the-art performance across various tasks. Recently, their effectiveness as embedding models has gained attention, marking a paradigm shift…

Computation and Language · Computer Science 2025-07-28 Chongyang Tao , Tao Shen , Shen Gao , Junshuo Zhang , Zhen Li , Kai Hua , Wenpeng Hu , Zhengwei Tao , Shuai Ma

Recent research indicates that pretraining cross-lingual language models on large-scale unlabeled texts yields significant performance improvements over various cross-lingual and low-resource tasks. Through training on one hundred languages…

Computation and Language · Computer Science 2020-11-24 Juntao Li , Ruidan He , Hai Ye , Hwee Tou Ng , Lidong Bing , Rui Yan

Post-training of Large Language Models (LLMs) is crucial for unlocking their task generalization potential and domain-specific capabilities. However, the current LLM post-training paradigm faces significant data challenges, including the…

Computation and Language · Computer Science 2025-10-31 Junyu Luo , Bohan Wu , Xiao Luo , Zhiping Xiao , Yiqiao Jin , Rong-Cheng Tu , Nan Yin , Yifan Wang , Jingyang Yuan , Wei Ju , Ming Zhang

Large Language Models(LLMs) excel in general tasks but struggle in specialized domains like healthcare due to limited domain-specific knowledge.Supervised Fine-Tuning(SFT) data construction for domain adaptation often relies on heuristic…

Machine Learning · Computer Science 2025-09-19 Hongxin Ding , Yue Fang , Runchuan Zhu , Xinke Jiang , Jinyang Zhang , Yongxin Xu , Xu Chu , Junfeng Zhao , Yasha Wang

Language models (LMs) have been instrumental for the rapid advance of natural language processing. This paper studies continual pre-training of LMs, in particular, continual domain-adaptive pre-training (or continual DAP-training). Existing…

Computation and Language · Computer Science 2023-04-13 Zixuan Ke , Yijia Shao , Haowei Lin , Tatsuya Konishi , Gyuhak Kim , Bing Liu

Analyzing vast textual data and summarizing key information from electronic health records imposes a substantial burden on how clinicians allocate their time. Although large language models (LLMs) have shown promise in natural language…

Text classification is crucial for applications such as sentiment analysis and toxic text filtering, but it still faces challenges due to the complexity and ambiguity of natural language. Recent advancements in deep learning, particularly…

Computation and Language · Computer Science 2024-08-29 Lingyu Gao

We investigate the effectiveness of fine-tuning large language models (LLMs) on small medical datasets for text classification and named entity recognition tasks. Using a German cardiology report dataset and the i2b2 Smoking Challenge…

Computation and Language · Computer Science 2025-03-28 Noah Losch , Lucas Plagwitz , Antonius Büscher , Julian Varghese