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The analysis of spatial data from biological imaging technology, such as imaging mass spectrometry (IMS) or imaging mass cytometry (IMC), is challenging because of a competitive sampling process which convolves signals from molecules in a…

Machine Learning · Statistics 2025-09-26 Joaquim Valerio Teixeira , Ed Reznik , Sudpito Banerjee , Wesley Tansey

Multiplex networks are collections of networks with identical nodes but distinct layers of edges. They are genuine representations for a large variety of real systems whose elements interact in multiple fashions or flavors. However,…

Physics and Society · Physics 2024-02-27 Daniel Kaiser , Siddharth Patwardhan , Minsuk Kim , Filippo Radicchi

Time-series datasets are central in machine learning with applications in numerous fields of science and engineering, such as biomedicine, Earth observation, and network analysis. Extensive research exists on state-space models (SSMs),…

Machine Learning · Computer Science 2024-06-17 Emilie Chouzenoux , Victor Elvira

Multi-omics integration offers novel insights into complex biological mechanisms by utlizing the fused information from various omics datasets. However, the inherent within- and inter-modality correlations in multi-omics data present…

Methodology · Statistics 2025-03-24 Zongrui Dai , Yvonne J. Huang , Gen Li

Latent Space (LS) network models project the nodes of a network on a $d$-dimensional latent space to achieve dimensionality reduction of the network while preserving its relevant features. Inference is often carried out within a Markov…

Computation · Statistics 2024-08-23 Roberto Casarin , Antonio Peruzzi

Graph Neural Networks (GNNs) are widely adopted in Web-related applications, serving as a core technique for learning from graph-structured data, such as text-attributed graphs. Yet in real-world scenarios, such graphs exhibit deficiencies…

Machine Learning · Computer Science 2025-10-03 Zhaoyan Wang , Zheng Gao , Arogya Kharel , In-Young Ko

Microbiome data analyses require statistical tools that can simultaneously decode microbes' reactions to the environment and interactions among microbes. We introduce CARlasso, the first user-friendly open-source and publicly available R…

Applications · Statistics 2021-07-30 Yunyi Shen , Claudia Solis-Lemus

Omic data are characterized by the presence of strong dependence structures that result either from data acquisition or from some underlying biological processes. In metabolomics, for instance, data resulting from Liquid Chromatography-Mass…

We propose an L1-penalized algorithm for fitting high-dimensional generalized linear mixed models. Generalized linear mixed models (GLMMs) can be viewed as an extension of generalized linear models for clustered observations. This…

Computation · Statistics 2014-06-03 Jürg Schelldorfer , Lukas Meier , Peter Bühlmann

In this work, we aim to address the challenging task of open set recognition (OSR). Many recent OSR methods rely on auto-encoders to extract class-specific features by a reconstruction strategy, requiring the network to restore the input…

Computer Vision and Pattern Recognition · Computer Science 2021-08-09 Xin Sun , Henghui Ding , Chi Zhang , Guosheng Lin , Keck-Voon Ling

Quantitative susceptibility mapping (QSM) involves acquisition and reconstruction of a series of images at multi-echo time points to estimate tissue field, which prolongs scan time and requires specific reconstruction technique. In this…

Image and Video Processing · Electrical Eng. & Systems 2022-11-03 Jinwei Zhang , Pascal Spincemaille , Hang Zhang , Thanh D. Nguyen , Chao Li , Jiahao Li , Ilhami Kovanlikaya , Mert R. Sabuncu , Yi Wang

Complex systems may contain heterogeneous types of variables that interact in a multi-level and multi-scale manner. In this context, high-level layers may considered as groups of variables interacting in lower-level layers. This is…

Quantitative Methods · Quantitative Biology 2018-11-28 Veronica Tozzo , Federico Tomasi , Margherita Squillario , Annalisa Barla

We introduce MIPS-Fusion, a robust and scalable online RGB-D reconstruction method based on a novel neural implicit representation -- multi-implicit-submap. Different from existing neural RGB-D reconstruction methods lacking either…

Computer Vision and Pattern Recognition · Computer Science 2023-08-25 Yijie Tang , Jiazhao Zhang , Zhinan Yu , He Wang , Kai Xu

The application of machine learning methods to analyze changes in gene expression patterns has recently emerged as a powerful approach in cancer research, enhancing our understanding of the molecular mechanisms underpinning cancer…

Machine Learning · Computer Science 2024-09-02 Fadi Alharbi , Aleksandar Vakanski , Murtada K. Elbashir , Mohanad Mohammed

Network graphs have become a popular tool to represent complex systems composed of many interacting subunits; especially in neuroscience, network graphs are increasingly used to represent and analyze functional interactions between neural…

Information Theory · Computer Science 2015-11-24 Patricia Wollstadt , Ulrich Meyer , Michael Wibral

Effectively modeling multimodal spatial omics data is critical for understanding tissue complexity and underlying biological mechanisms. While spatial transcriptomics, proteomics, and epigenomics capture molecular features, they lack…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Yongjun Xiao , Dian Meng , Xinlei Huang , Yanran Liu , Shiwei Ruan , Ziyue Qiao , Xubin Zheng

In recent years, there is a growing interest in combining techniques attributed to the areas of Statistics and Machine Learning in order to obtain the benefits of both approaches. In this article, the statistical technique lasso for…

Machine Learning · Statistics 2023-09-08 David Delgado , Ernesto Curbelo , Danae Carreras

Optical approaches have made great strides towards the goal of high-speed, energy-efficient computing necessary for modern deep learning and AI applications. Read-in and read-out of data, however, limit the overall performance of existing…

Emerging Technologies · Computer Science 2024-02-06 Alexander Song , Sai Nikhilesh Murty Kottapalli , Rahul Goyal , Bernhard Schölkopf , Peer Fischer

Predicting clinical variables from whole-brain neuroimages is a high dimensional problem that requires some type of feature selection or extraction. Penalized regression is a popular embedded feature selection method for high dimensional…

Methodology · Statistics 2018-02-27 Joanne C. Beer , Howard J. Aizenstein , Stewart J. Anderson , Robert T. Krafty

In this paper, we consider the problem of estimating multiple graphical models simultaneously using the fused lasso penalty, which encourages adjacent graphs to share similar structures. A motivating example is the analysis of brain…

Machine Learning · Computer Science 2014-01-03 Sen Yang , Zhaosong Lu , Xiaotong Shen , Peter Wonka , Jieping Ye