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Recent advances in Large Language Models (LLMs) have presented new opportunities for integrating Artificial General Intelligence (AGI) into biological research and education. This study evaluated the capabilities of leading LLMs, including…

Computation and Language · Computer Science 2023-11-15 Xinyu Gong , Jason Holmes , Yiwei Li , Zhengliang Liu , Qi Gan , Zihao Wu , Jianli Zhang , Yusong Zou , Yuxi Teng , Tian Jiang , Hongtu Zhu , Wei Liu , Tianming Liu , Yajun Yan

Biomedical literature often uses complex language and inaccessible professional terminologies. That is why simplification plays an important role in improving public health literacy. Applying Natural Language Processing (NLP) models to…

Computation and Language · Computer Science 2024-03-19 Zihao Li , Samuel Belkadi , Nicolo Micheletti , Lifeng Han , Matthew Shardlow , Goran Nenadic

The emergence of Small Language Models (SLMs) as privacy-preserving alternatives for sensitive applications raises a fundamental question about their inherent understanding capabilities compared to Large Language Models (LLMs). This paper…

Computation and Language · Computer Science 2025-07-15 Hong Jia , Shiya Fu , Feng Xia , Vassilis Kostakos , Ting Dang

While recent advancements in commercial large language models (LM) have shown promising results in medical tasks, their closed-source nature poses significant privacy and security concerns, hindering their widespread use in the medical…

Computation and Language · Computer Science 2024-07-02 Hyunjae Kim , Hyeon Hwang , Jiwoo Lee , Sihyeon Park , Dain Kim , Taewhoo Lee , Chanwoong Yoon , Jiwoong Sohn , Donghee Choi , Jaewoo Kang

Relations such as "is influenced by", "is known for" or "is a competitor of" are inherently graded: we can rank entity pairs based on how well they satisfy these relations, but it is hard to draw a line between those pairs that satisfy them…

Computation and Language · Computer Science 2024-02-01 Asahi Ushio , Jose Camacho Collados , Steven Schockaert

Pre-trained language models (PLMs) have achieved remarkable success in NLP tasks. Despite the great success, mainstream solutions largely follow the pre-training then finetuning paradigm, which brings in both high deployment costs and low…

Computation and Language · Computer Science 2023-05-03 Xiang Li , Xin Jiang , Xuying Meng , Aixin Sun , Yequan Wang

Understanding the conversation abilities of Large Language Models (LLMs) can help lead to its more cautious and appropriate deployment. This is especially important for safety-critical domains like mental health, where someone's life may…

Computation and Language · Computer Science 2024-03-18 Alexander Marrapese , Basem Suleiman , Imdad Ullah , Juno Kim

Purpose: Enhanced health literacy has been linked to better health outcomes; however, few interventions have been studied. We investigate whether large language models (LLMs) can serve as a medium to improve health literacy in children and…

Computation and Language · Computer Science 2023-11-17 Kanhai S. Amin , Linda Mayes , Pavan Khosla , Rushabh Doshi

Background: Log messages provide valuable information about the status of software systems. This information is provided in an unstructured fashion and automated approaches are applied to extract relevant parameters. To ease this process,…

Software Engineering · Computer Science 2024-09-05 Merve Astekin , Max Hort , Leon Moonen

The rapid development of large language models (LLMs) has transformed many industries, including healthcare. However, previous medical LLMs have largely focused on leveraging general medical knowledge to provide responses, without…

Computation and Language · Computer Science 2024-12-23 Ruize Shi , Hong Huang , Wei Zhou , Kehan Yin , Kai Zhao , Yun Zhao

Developing effective biomedical retrieval models is important for excelling at knowledge-intensive biomedical tasks but still challenging due to the deficiency of sufficient publicly annotated biomedical data and computational resources. We…

Computation and Language · Computer Science 2024-10-07 Ran Xu , Wenqi Shi , Yue Yu , Yuchen Zhuang , Yanqiao Zhu , May D. Wang , Joyce C. Ho , Chao Zhang , Carl Yang

Physicians considering clinical trials for their patients are met with the laborious process of checking many text based eligibility criteria. Large Language Models (LLMs) have shown to perform well for clinical information extraction and…

Machine Learning · Computer Science 2023-06-30 Danny M. den Hamer , Perry Schoor , Tobias B. Polak , Daniel Kapitan

The modeling of bio-molecular system across molecular scales remains a central challenge in scientific research. Large language models (LLMs) are increasingly applied to bio-molecular discovery, yet systematic evaluation across multi-scale…

Machine Learning · Computer Science 2026-04-07 Yaxin Xu , Yue Zhou , Tianyu Zhao , Fengwei An , Zhixiang Ren

Large Language Models (LLMs), typified by OpenAI's GPT, have marked a significant advancement in artificial intelligence. Trained on vast amounts of text data, LLMs are capable of understanding and generating human-like text across a…

Artificial Intelligence · Computer Science 2024-10-29 Haochen Zhang , Yuyang Dong , Chuan Xiao , Masafumi Oyamada

Frontier large language models (LLMs), such as GPT-5, Claude 4.5, Gemini 3, Llama 4, and DeepSeek-R1, represent a transformative class of AI tools capable of revolutionizing various aspects of healthcare by generating human-like responses…

Large language models (LLMs) like ChatGPT can generate and revise text with human-level performance. These models come with clear limitations: they can produce inaccurate information, reinforce existing biases, and be easily misused. Yet,…

Computation and Language · Computer Science 2025-07-04 Dmitry Kobak , Rita González-Márquez , Emőke-Ágnes Horvát , Jan Lause

Natural language processing (NLP) is a key technology to extract important patient information from clinical narratives to support healthcare applications. The rapid development of large language models (LLMs) has revolutionized many NLP…

Computation and Language · Computer Science 2025-09-08 Cheng Peng , Xinyu Dong , Mengxian Lyu , Daniel Paredes , Yaoyun Zhang , Yonghui Wu

Large Language Models (LLMs) have demonstrated remarkable capabilities in reasoning and generation, serving as the foundation for advanced persona simulation and Role-Playing Language Agents (RPLAs). However, achieving authentic alignment…

Computation and Language · Computer Science 2026-04-20 Xintao Wang , Jian Yang , Weiyuan Li , Rui Xie , Jen-tse Huang , Jun Gao , Shuai Huang , Yueping Kang , Yuanli Gou , Hongwei Feng , Yanghua Xiao

Trained on massive publicly available data, large language models (LLMs) have demonstrated tremendous success across various fields. While more data contributes to better performance, a disconcerting reality is that high-quality public data…

Machine Learning · Computer Science 2024-02-13 Rui Ye , Wenhao Wang , Jingyi Chai , Dihan Li , Zexi Li , Yinda Xu , Yaxin Du , Yanfeng Wang , Siheng Chen