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With the growing amount of text in health data, there have been rapid advances in large pre-trained models that can be applied to a wide variety of biomedical tasks with minimal task-specific modifications. Emphasizing the cost of these…

A prominent achievement of natural language processing (NLP) is its ability to understand and generate meaningful human language. This capability relies on complex feedforward transformer block architectures pre-trained on large language…

Computation and Language · Computer Science 2025-11-11 Ronit D. Gross , Yarden Tzach , Tal Halevi , Ella Koresh , Ido Kanter

While large language models have facilitated breakthroughs in many applications of artificial intelligence, their inherent largeness makes them computationally expensive and challenging to deploy in resource-constrained settings. In this…

Large language models (LLMs) enable system builders today to create competent NLP systems through prompting, where they only need to describe the task in natural language and provide a few examples. However, in other ways, LLMs are a step…

Computation and Language · Computer Science 2023-08-24 Vijay Viswanathan , Chenyang Zhao , Amanda Bertsch , Tongshuang Wu , Graham Neubig

Language is essentially a complex, intricate system of human expressions governed by grammatical rules. It poses a significant challenge to develop capable AI algorithms for comprehending and grasping a language. As a major approach,…

Large Language Models (LLMs) have demonstrated remarkable capabilities across various domains and are moving towards more specialized areas. Recent advanced proprietary models such as GPT-4 and Gemini have achieved significant advancements…

Computation and Language · Computer Science 2024-10-30 Kaiyan Zhang , Sihang Zeng , Ermo Hua , Ning Ding , Zhang-Ren Chen , Zhiyuan Ma , Haoxin Li , Ganqu Cui , Biqing Qi , Xuekai Zhu , Xingtai Lv , Hu Jinfang , Zhiyuan Liu , Bowen Zhou

Participant recruitment based on unstructured medical texts such as clinical notes and radiology reports has been a challenging yet important task for the cohort establishment in clinical research. Recently, Large Language Models (LLMs)…

Computation and Language · Computer Science 2023-07-24 Zihan Guan , Zihao Wu , Zhengliang Liu , Dufan Wu , Hui Ren , Quanzheng Li , Xiang Li , Ninghao Liu

Background: Biomedical entity normalization is critical to biomedical research because the richness of free-text clinical data, such as progress notes, can often be fully leveraged only after translating words and phrases into structured…

Computation and Language · Computer Science 2024-05-27 Nicholas J Dobbins

Recent artificial intelligence (AI) systems have reached milestones in "grand challenges" ranging from Go to protein-folding. The capability to retrieve medical knowledge, reason over it, and answer medical questions comparably to…

Large Language Models (LLMs) are at the forefront of NLP achievements but fall short in dealing with shortcut learning, factual inconsistency, and vulnerability to adversarial inputs.These shortcomings are especially critical in medical…

Computation and Language · Computer Science 2024-04-09 Mael Jullien , Marco Valentino , André Freitas

Pre-trained Language Models (PLMs) have proven to be beneficial for various downstream NLP tasks. Recently, GPT-3, with 175 billion parameters and 570GB training data, drew a lot of attention due to the capacity of few-shot (even zero-shot)…

Drug repurposing is often framed as a candidate identification task, but existing approaches provide limited guidance for distinguishing biologically plausible candidates from historically well-connected ones. Here we introduce DrugKLM, a…

Pre-trained language models (LMs) have become ubiquitous in solving various natural language processing (NLP) tasks. There has been increasing interest in what knowledge these LMs contain and how we can extract that knowledge, treating LMs…

Computation and Language · Computer Science 2021-09-16 Mujeen Sung , Jinhyuk Lee , Sean Yi , Minji Jeon , Sungdong Kim , Jaewoo Kang

The use of NLP in the realm of financial technology is broad and complex, with applications ranging from sentiment analysis and named entity recognition to question answering. Large Language Models (LLMs) have been shown to be effective on…

Large language models (LLMs) have shown remarkable performance on many tasks in different domains. However, their performance in closed-book biomedical machine reading comprehension (MRC) has not been evaluated in depth. In this work, we…

Computation and Language · Computer Science 2024-10-28 Shubham Vatsal , Ayush Singh

The use of large language models (LLMs) in healthcare is gaining popularity, but their practicality and safety in clinical settings have not been thoroughly assessed. In high-stakes environments like medical settings, trust and safety are…

Artificial Intelligence · Computer Science 2023-06-29 Salmonn Talebi , Elizabeth Tong , Mohammad R. K. Mofrad

Despite the success of large language models (LLMs) on general-purpose tasks, their performance in highly specialized domains such as biomedicine remains unsatisfactory. A key limitation is the inability of LLMs to effectively leverage…

Computation and Language · Computer Science 2026-05-08 Xin Gao , Ruiyi Zhang , Meixi Du , Peijia Qin , Pengtao Xie

Large language models (LLMs) have recently emerged as powerful tools, finding many medical applications. LLMs' ability to coalesce vast amounts of information from many sources to generate a response-a process similar to that of a human…

There has been an influx of biomedical domain-specific language models, showing language models pre-trained on biomedical text perform better on biomedical domain benchmarks than those trained on general domain text corpora such as…

Computation and Language · Computer Science 2020-10-15 Hoo-Chang Shin , Yang Zhang , Evelina Bakhturina , Raul Puri , Mostofa Patwary , Mohammad Shoeybi , Raghav Mani

Although large language models (LLMs) often produce impressive outputs, it remains unclear how they perform in real-world scenarios requiring strong reasoning skills and expert domain knowledge. We set out to investigate whether close- and…

Computation and Language · Computer Science 2023-12-27 Valentin Liévin , Christoffer Egeberg Hother , Andreas Geert Motzfeldt , Ole Winther