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Recently, deep learning-based methods achieved promising performance in nuclei detection and classification applications. However, training deep learning-based methods requires a large amount of pixel-wise annotated data, which is…

Image and Video Processing · Electrical Eng. & Systems 2024-01-17 Nazanin Moradinasab , Rebecca A. Deaton , Laura S. Shankman , Gary K. Owens , Donald E. Brown

Intensive Care Units (ICU) require comprehensive patient data integration for enhanced clinical outcome predictions, crucial for assessing patient conditions. Recent deep learning advances have utilized patient time series data, and fusion…

Machine Learning · Computer Science 2023-11-14 Samyak Jain , Manuel Burger , Gunnar Rätsch , Rita Kuznetsova

Analysis of longitudinal Electronic Health Record (EHR) data is an important goal for precision medicine. Difficulty in applying Machine Learning (ML) methods, either predictive or unsupervised, stems in part from the heterogeneity and…

Quantitative Methods · Quantitative Biology 2022-04-18 Alan D. Kaplan , Uttara Tipnis , Jean C. Beckham , Nathan A. Kimbrel , David W. Oslin , Benjamin H. McMahon

Learning medical visual representations directly from paired images and reports through multimodal self-supervised learning has emerged as a novel and efficient approach to digital diagnosis in recent years. However, existing models suffer…

Computer Vision and Pattern Recognition · Computer Science 2025-06-16 Libin Lan , Hongxing Li , Zunhui Xia , Juan Zhou , Xiaofei Zhu , Yongmei Li , Yudong Zhang , Xin Luo

Contrastive Language-Image Pretraining (CLIP) models excel at understanding image-text relationships but struggle with adapting to new data without forgetting prior knowledge. To address this, models are typically fine-tuned using both new…

Machine Learning · Computer Science 2026-05-06 Ryan King , Gang Li , Bobak Mortazavi , Tianbao Yang

Clinical notes contain rich patient information, such as diagnoses or medications, making them valuable for patient representation learning. Recent advances in large language models have further improved the ability to extract meaningful…

Machine Learning · Computer Science 2025-09-23 Zihan Liang , Ziwen Pan , Ruoxuan Xiong

Doctors often make diagonostic decisions based on patient's image scans, such as magnetic resonance imaging (MRI), and patient's electronic health records (EHR) such as age, gender, blood pressure and so on. Despite a lot of automatic…

Computer Vision and Pattern Recognition · Computer Science 2021-12-23 Cheng Jiang , Yihao Chen , Jianbo Chang , Ming Feng , Renzhi Wang , Jianhua Yao

The success of deep learning heavily depends on the availability of large labeled training sets. However, it is hard to get large labeled datasets in medical image domain because of the strict privacy concern and costly labeling efforts.…

Computer Vision and Pattern Recognition · Computer Science 2021-09-30 Dewen Zeng , Yawen Wu , Xinrong Hu , Xiaowei Xu , Haiyun Yuan , Meiping Huang , Jian Zhuang , Jingtong Hu , Yiyu Shi

We present a collaborative learning method called Mutual Contrastive Learning (MCL) for general visual representation learning. The core idea of MCL is to perform mutual interaction and transfer of contrastive distributions among a cohort…

Computer Vision and Pattern Recognition · Computer Science 2022-01-19 Chuanguang Yang , Zhulin An , Linhang Cai , Yongjun Xu

Quantitative disease severity scoring in medical imaging is costly, time-consuming, and subject to inter-reader variability. At the same time, clinical archives contain far more longitudinal imaging data than expert-annotated severity…

This paper presents a novel positive and negative set selection strategy for contrastive learning of medical images based on labels that can be extracted from clinical data. In the medical field, there exists a variety of labels for data…

Computer Vision and Pattern Recognition · Computer Science 2022-11-10 Kiran Kokilepersaud , Mohit Prabhushankar , Ghassan AlRegib

Automatic code review (ACR), aiming to relieve manual inspection costs, is an indispensable and essential task in software engineering. The existing works only use the source code fragments to predict the results, missing the exploitation…

Software Engineering · Computer Science 2022-05-31 Bingting Wu , Xiaofang Zhang

Multimodal clinical records contain structured measurements and clinical notes recorded over time, offering rich temporal information about the evolution of patient health. Yet these observations are sparse, and whether they are recorded…

Machine Learning · Computer Science 2026-04-24 Zihan Liang , Ziwen Pan , Ruoxuan Xiong

Accurate prognosis of non-small cell lung cancer (NSCLC) patients undergoing immunotherapy is essential for personalized treatment planning, enabling informed patient decisions, and improving both treatment outcomes and quality of life.…

Computer Vision and Pattern Recognition · Computer Science 2025-08-22 Qilong Xing , Zikai Song , Bingxin Gong , Lian Yang , Junqing Yu , Wei Yang

Electronic health records (EHR) consist of longitudinal clinical observations portrayed with sparsity, irregularity, and high-dimensionality, which become major obstacles in drawing reliable downstream clinical outcomes. Although there…

Machine Learning · Computer Science 2020-11-17 Ahmad Wisnu Mulyadi , Eunji Jun , Heung-Il Suk

This paper proposes a method for representation learning of multimodal data using contrastive losses. A traditional approach is to contrast different modalities to learn the information shared between them. However, that approach could fail…

Computer Vision and Pattern Recognition · Computer Science 2021-07-07 Yunze Liu , Qingnan Fan , Shanghang Zhang , Hao Dong , Thomas Funkhouser , Li Yi

In medical time series disease diagnosis, two key challenges are identified.First, the high annotation cost of medical data leads to overfitting in models trained on label-limited, single-center datasets. To address this, we propose…

Machine Learning · Computer Science 2025-01-31 Yifan Wang , Hongfeng Ai , Ruiqi Li , Maowei Jiang , Cheng Jiang , Chenzhong Li

This work discusses the use of contrastive learning and deep learning for diagnosing cardiovascular diseases from electrocardiography (ECG) signals. While the ECG signals usually contain 12 leads (channels), many healthcare facilities and…

Signal Processing · Electrical Eng. & Systems 2023-04-24 Tue M. Cao , Nhat H. Tran , Phi Le Nguyen , Hieu Pham

Multi-modal entity alignment aims to identify equivalent entities between two different multi-modal knowledge graphs, which consist of structural triples and images associated with entities. Most previous works focus on how to utilize and…

Computation and Language · Computer Science 2022-09-05 Zhenxi Lin , Ziheng Zhang , Meng Wang , Yinghui Shi , Xian Wu , Yefeng Zheng

Cross-modal representation learning learns a shared embedding between two or more modalities to improve performance in a given task compared to using only one of the modalities. Cross-modal representation learning from different data types…

Machine Learning · Computer Science 2023-09-12 Felix Ott , David Rügamer , Lucas Heublein , Bernd Bischl , Christopher Mutschler
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