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Background: Photoacoustic Microscopy (PAM) integrates optical and acoustic imaging, offering enhanced penetration depth for detecting optical-absorbing components in tissues. Nonetheless, challenges arise in scanning large areas with high…

Diffusion models have recently emerged as powerful generative models in medical imaging. However, it remains a major challenge to combine these data-driven models with domain knowledge to guide brain imaging problems. In neuroimaging,…

In medical imaging, the diffusion models have shown great potential for synthetic image generation tasks. However, these approaches often lack the interpretable connections between the generated and real images and can create anatomically…

Blind image restoration remains a significant challenge in low-level vision tasks. Recently, denoising diffusion models have shown remarkable performance in image synthesis. Guided diffusion models, leveraging the potent generative priors…

Fourier Ptychographic Microscopy (FPM) is a computational imaging technique that enables high-resolution imaging over a large field of view. However, its application in the biomedical field has been limited due to the long image…

Supervised machine learning has enabled accurate pathology detection in brain MRI, but requires training data from diseased subjects that may not be readily available in some scenarios, for example, in the case of rare diseases.…

Positron emission tomography (PET) reconstruction has become an ill-posed inverse problem due to low-count projection data, and a robust algorithm is urgently required to improve imaging quality. Recently, the deep image prior (DIP) has…

Pseudo-healthy image inpainting is an essential preprocessing step for analyzing pathological brain MRI scans. Most current inpainting methods favor slice-wise 2D models for their high in-plane fidelity, but their independence across slices…

The integration of multimodal medical imaging can provide complementary and comprehensive information for the diagnosis of Alzheimer's disease (AD). However, in clinical practice, since positron emission tomography (PET) is often missing,…

Computer-assisted diagnosis (CAD) based on deep learning has become a crucial diagnostic technology in the medical industry, effectively improving diagnosis accuracy. However, the scarcity of brain tumor Magnetic Resonance (MR) image…

Purpose: Neural network image reconstruction directly from measurement data is a relatively new field of research, that until now has been limited to producing small single-slice images (e.g., 1x128x128). This paper proposes a novel and…

Diffusion Weighted Imaging (DWI) is an advanced imaging technique commonly used in neuroscience and neurological clinical research through a Diffusion Tensor Imaging (DTI) model. Volumetric scalar metrics including fractional anisotropy,…

Based on the Denoising Diffusion Probabilistic Model (DDPM), medical image segmentation can be described as a conditional image generation task, which allows to compute pixel-wise uncertainty maps of the segmentation and allows an implicit…

Restoring degraded music signals is essential to enhance audio quality for downstream music manipulation. Recent diffusion-based music restoration methods have demonstrated impressive performance, and among them, diffusion posterior…

Diffusion-weighted magnetic resonance imaging (DW-MRI) is a critical imaging method for capturing and modeling tissue microarchitecture at a millimeter scale. A common practice to model the measured DW-MRI signal is via fiber orientation…

Recent advances in diffusion models have demonstrated exceptional performance in generative tasks across vari-ous fields. In positron emission tomography (PET), the reduction in tracer dose leads to information loss in sino-grams. Using…

Computed tomography (CT) involves a patient's exposure to ionizing radiation. To reduce the radiation dose, we can either lower the X-ray photon count or down-sample projection views. However, either of the ways often compromises image…

Physics-driven artificial intelligence (PD-AI) reconstruction methods have emerged as the state-of-the-art for accelerating MRI scans, enabling higher spatial and temporal resolutions. However, the high resolution of these scans generates…

Patients undergoing a mechanical thrombectomy procedure usually have a multi-detector CT (MDCT) scan before and after the intervention. The image quality of the flat panel detector CT (FDCT) present in the intervention room is generally…

Diffusion models have enabled remarkably high-quality medical image generation, yet it is challenging to enforce anatomical constraints in generated images. To this end, we propose a diffusion model-based method that supports…