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Confocal microscopy is the standard approach for obtaining volumetric images of a sample with high axial and lateral resolution, especially when dealing with scattering samples. Unfortunately, a confocal microscope is quite expensive…

In this paper, we study the cross-modal image retrieval, where the inputs contain a source image plus some text that describes certain modifications to this image and the desired image. Prior work usually uses a three-stage strategy to…

Computer Vision and Pattern Recognition · Computer Science 2021-03-11 Chunbin Gu , Jiajun Bu , Xixi Zhou , Chengwei Yao , Dongfang Ma , Zhi Yu , Xifeng Yan

Raman spectroscopy enables non-destructive, label-free imaging with unprecedented molecular contrast but is limited by slow data acquisition, largely preventing high-throughput imaging applications. Here, we present a comprehensive…

Image and Video Processing · Electrical Eng. & Systems 2021-12-02 Conor C. Horgan , Magnus Jensen , Anika Nagelkerke , Jean-Phillipe St-Pierre , Tom Vercauteren , Molly M. Stevens , Mads S. Bergholt

Fluorescence microscopy has enabled a dramatic development in modern biology by visualizing biological organisms with micrometer scale resolution. However, due to the diffraction limit, sub-micron/nanometer features are difficult to…

Image and Video Processing · Electrical Eng. & Systems 2021-03-10 Varun Mannam , Yide Zhang , Xiaotong Yuan , Scott Howard

We demonstrate that a deep neural network can significantly improve optical microscopy, enhancing its spatial resolution over a large field-of-view and depth-of-field. After its training, the only input to this network is an image acquired…

Machine Learning · Computer Science 2017-11-21 Yair Rivenson , Zoltan Gorocs , Harun Gunaydin , Yibo Zhang , Hongda Wang , Aydogan Ozcan

Multimodal Magnetic Resonance (MR) Imaging plays a crucial role in disease diagnosis due to its ability to provide complementary information by analyzing a relationship between multimodal images on the same subject. Acquiring all MR…

Image and Video Processing · Electrical Eng. & Systems 2024-02-02 Jihoon Cho , Xiaofeng Liu , Fangxu Xing , Jinsong Ouyang , Georges El Fakhri , Jinah Park , Jonghye Woo

Deep learning has thrived by training on large-scale datasets. However, in many applications, as for medical image diagnosis, getting massive amount of data is still prohibitive due to privacy, lack of acquisition homogeneity and annotation…

Computer Vision and Pattern Recognition · Computer Science 2020-10-21 Lia Morra , Luca Piano , Fabrizio Lamberti , Tatiana Tommasi

Magnetic resonance imaging (MRI) offers superb-quality images, but its accessibility is limited by high costs, posing challenges for patients requiring longitudinal care. Low-field MRI provides affordable imaging with low-cost devices but…

Image and Video Processing · Electrical Eng. & Systems 2025-05-06 Tal Oved , Beatrice Lena , Chloé F. Najac , Sheng Shen , Matthew S. Rosen , Andrew Webb , Efrat Shimron

Multi-modality images have been widely used and provide comprehensive information for medical image analysis. However, acquiring all modalities among all institutes is costly and often impossible in clinical settings. To leverage more…

Image and Video Processing · Electrical Eng. & Systems 2022-09-13 Qi Chang , Hui Qu , Zhennan Yan , Yunhe Gao , Lohendran Baskaran , Dimitris Metaxas

Deep learning-based computer-aided diagnosis is gradually deployed to review and analyze medical images. However, this paradigm is restricted in real-world clinical applications due to the poor robustness and generalization. The issue is…

Computer Vision and Pattern Recognition · Computer Science 2022-03-22 Yurong Chen

Medical imaging plays a vital role in modern diagnostics; however, interpreting high-resolution radiological data remains time-consuming and susceptible to variability among clinicians. Traditional image processing techniques often lack the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Melika Filvantorkaman , Maral Filvan Torkaman

Deep learning-based methods in computational microscopy have been shown to be powerful but in general face some challenges due to limited generalization to new types of samples and requirements for large and diverse training data. Here, we…

Image and Video Processing · Electrical Eng. & Systems 2022-06-13 Luzhe Huang , Xilin Yang , Tairan Liu , Aydogan Ozcan

Multi-modality is widely used in medical imaging, because it can provide multiinformation about a target (tumor, organ or tissue). Segmentation using multimodality consists of fusing multi-information to improve the segmentation. Recently,…

Image and Video Processing · Electrical Eng. & Systems 2020-07-17 Tongxue Zhou , Su Ruan , Stéphane Canu

Volumetric imaging by fluorescence microscopy is often limited by anisotropic spatial resolution from inferior axial resolution compared to the lateral resolution. To address this problem, here we present a deep-learning-enabled…

Computer Vision and Pattern Recognition · Computer Science 2022-07-06 Hyoungjun Park , Myeongsu Na , Bumju Kim , Soohyun Park , Ki Hean Kim , Sunghoe Chang , Jong Chul Ye

Hyperspectral imaging is a powerful bioimaging tool which can uncover novel insights, thanks to its sensitivity to the intrinsic properties of materials. However, this enhanced contrast comes at the cost of system complexity, constrained by…

We present a simple deep learning-based framework commonly used in computer vision and demonstrate its effectiveness for cross-dataset transfer learning in mental imagery decoding tasks that are common in the field of Brain-Computer…

Computer Vision and Pattern Recognition · Computer Science 2023-11-29 Pierre Guetschel , Michael Tangermann

Imaging and hyperspectral data analysis is central to progress across biology, medicine, chemistry, and physics. The core challenge lies in converting high-resolution or high-dimensional datasets into interpretable representations that…

Image and Video Processing · Electrical Eng. & Systems 2025-12-29 Kamyar Barakati , Yu Liu , Utkarsh Pratiush , Boris N. Slautin , Sergei V. Kalinin

Hyperspectral and multispectral image fusion allows us to overcome the hardware limitations of hyperspectral imaging systems inherent to their lower spatial resolution. Nevertheless, existing algorithms usually fail to consider realistic…

Image and Video Processing · Electrical Eng. & Systems 2023-07-19 Xiuheng Wang , Ricardo Augusto Borsoi , Cédric Richard , Jie Chen

The ability to automatically learn task specific feature representations has led to a huge success of deep learning methods. When large training data is scarce, such as in medical imaging problems, transfer learning has been very effective.…

Computer Vision and Pattern Recognition · Computer Science 2017-04-21 Hariharan Ravishankar , Prasad Sudhakar , Rahul Venkataramani , Sheshadri Thiruvenkadam , Pavan Annangi , Narayanan Babu , Vivek Vaidya

Lightweight deep learning models offer substantial reductions in computational cost and environmental impact, making them crucial for scientific applications. We present a lightweight CycleGAN for modality transfer in fluorescence…

Computer Vision and Pattern Recognition · Computer Science 2025-10-20 Mohammad Soltaninezhad , Yashar Rouzbahani , Jhonatan Contreras , Rohan Chippalkatti , Daniel Kwaku Abankwa , Christian Eggeling , Thomas Bocklitz
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