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The rapid advancement of Large Language Models (LLMs) is reshaping software engineering by profoundly influencing coding, documentation, and system maintenance practices. As these tools become deeply embedded in developers' daily workflows,…

Software Engineering · Computer Science 2025-12-29 Vítor Mateus de Brito , Kleinner Farias

Recent developments in large language models (LLMs) have unlocked new opportunities for healthcare, from information synthesis to clinical decision support. These new LLMs are not just capable of modeling language, but can also act as…

Human-Computer Interaction · Computer Science 2023-09-21 Nikita Mehandru , Brenda Y. Miao , Eduardo Rodriguez Almaraz , Madhumita Sushil , Atul J. Butte , Ahmed Alaa

Large Language Models (LLMs) have garnered considerable interest due to their impressive natural language capabilities, which in conjunction with various emergent properties make them versatile tools in workflows ranging from complex code…

Materials Science · Physics 2024-10-22 Ge Lei , Ronan Docherty , Samuel J. Cooper

This paper presents a novel design of a multi-agent system framework that applies large language models (LLMs) to automate the parametrization of simulation models in digital twins. This framework features specialized LLM agents tasked with…

Artificial Intelligence · Computer Science 2024-07-23 Yuchen Xia , Daniel Dittler , Nasser Jazdi , Haonan Chen , Michael Weyrich

The integration of Large Language Models (LLMs) into the drug discovery and development field marks a significant paradigm shift, offering novel methodologies for understanding disease mechanisms, facilitating drug discovery, and optimizing…

Quantitative Methods · Quantitative Biology 2024-09-10 Yizhen Zheng , Huan Yee Koh , Maddie Yang , Li Li , Lauren T. May , Geoffrey I. Webb , Shirui Pan , George Church

Large language models (LLMs) process and predict sequences containing text to answer questions, and address tasks including document summarization, providing recommendations, writing software and solving quantitative problems. We provide a…

Numerical Analysis · Mathematics 2026-02-02 Ricardo Baptista , Andrew Stuart , Son Tran

Large Language Models (LLMs) have seen significant use in domains such as natural language processing and computer vision. Going beyond text, image and graphics, LLMs present a significant potential for analysis of time series data,…

Machine Learning · Computer Science 2024-05-08 Xiyuan Zhang , Ranak Roy Chowdhury , Rajesh K. Gupta , Jingbo Shang

Large language model (LLM) has recently been considered a promising technique for many fields. This work explores LLM-based wireless network optimization via in-context learning. To showcase the potential of LLM technologies, we consider…

Systems and Control · Electrical Eng. & Systems 2025-06-17 Hao Zhou , Chengming Hu , Dun Yuan , Ye Yuan , Di Wu , Xue Liu , Charlie Zhang

Research on long non-coding RNAs (lncRNAs) has garnered significant attention due to their critical roles in gene regulation and disease mechanisms. However, the complexity and diversity of lncRNA sequences, along with the limited knowledge…

Genomics · Quantitative Biology 2024-11-07 Wei Wang , Zhichao Hou , Xiaorui Liu , Xinxia Peng

Large language models (LLMs) and large multimodal models (LMMs) have achieved unprecedented breakthrough, showcasing remarkable capabilities in natural language understanding, generation, and complex reasoning. This transformative potential…

Machine Learning · Computer Science 2025-10-24 Hyun Jong Yang , Hyunsoo Kim , Hyeonho Noh , Seungnyun Kim , Byonghyo Shim

Large Language Models (LLMs) are transforming artificial intelligence, enabling autonomous agents to perform diverse tasks across various domains. These agents, proficient in human-like text comprehension and generation, have the potential…

Artificial Intelligence · Computer Science 2024-04-10 Saikat Barua

In the fast-evolving domain of artificial intelligence, large language models (LLMs) such as GPT-3 and GPT-4 are revolutionizing the landscapes of finance, healthcare, and law: domains characterized by their reliance on professional…

Computation and Language · Computer Science 2024-11-25 Zhiyu Zoey Chen , Jing Ma , Xinlu Zhang , Nan Hao , An Yan , Armineh Nourbakhsh , Xianjun Yang , Julian McAuley , Linda Petzold , William Yang Wang

The growing demand for large language models (LLMs) with tunable reasoning capabilities in many real-world applications highlights a critical need for methods that can efficiently produce a spectrum of models balancing reasoning depth and…

Artificial Intelligence · Computer Science 2025-09-30 Xiaochong Lan , Yu Zheng , Shiteng Cao , Yong Li

Large Language Models (LLMs) are the cornerstone in automating Requirements Engineering (RE) tasks, underpinning recent advancements in the field. Their pre-trained comprehension of natural language is pivotal for effectively tailoring them…

Software Engineering · Computer Science 2024-05-16 Andreas Vogelsang , Jannik Fischbach

Supply Chain Management requires addressing a variety of complex decision-making challenges, from sourcing strategies to planning and execution. Over the last few decades, advances in computation and information technologies have enabled…

Artificial Intelligence · Computer Science 2025-07-30 David Simchi-Levi , Konstantina Mellou , Ishai Menache , Jeevan Pathuri

Better understanding of Large Language Models' (LLMs) legal analysis abilities can contribute to improving the efficiency of legal services, governing artificial intelligence, and leveraging LLMs to identify inconsistencies in law. This…

Computation and Language · Computer Science 2023-06-13 John J. Nay , David Karamardian , Sarah B. Lawsky , Wenting Tao , Meghana Bhat , Raghav Jain , Aaron Travis Lee , Jonathan H. Choi , Jungo Kasai

Scientific workflow systems are increasingly popular for expressing and executing complex data analysis pipelines over large datasets, as they offer reproducibility, dependability, and scalability of analyses by automatic parallelization on…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-07-09 Mario Sänger , Ninon De Mecquenem , Katarzyna Ewa Lewińska , Vasilis Bountris , Fabian Lehmann , Ulf Leser , Thomas Kosch

This chapter explores the application of Large Language Models in the legal domain, showcasing their potential to optimise and augment traditional legal tasks by analysing possible use cases, such as assisting in interpreting statutes,…

Computation and Language · Computer Science 2025-12-12 Simone Corbo

This comprehensive literature review examines the emerging applications of Large Language Models (LLMs) in power system engineering. Through a systematic analysis of recent research published between 2020 and 2025, we explore how LLMs are…

Systems and Control · Electrical Eng. & Systems 2025-12-16 Muhammad Sarwar , Muhammad Rizwan , Mubushra Aziz , Abdul Rehman Sudais

Large language models (LLMs) are beginning to reshape how chemists plan and run reactions in organic synthesis. Trained on millions of reported transformations, these text-based models can propose synthetic routes, forecast reaction…

Artificial Intelligence · Computer Science 2025-08-08 Kartar Kumar Lohana Tharwani , Rajesh Kumar , Sumita , Numan Ahmed , Yong Tang