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Generative models have achieved remarkable progress with the emergence of flow matching (FM). It has demonstrated strong generative capabilities and attracted significant attention as a simulation-free flow-based framework capable of…

Computer Vision and Pattern Recognition · Computer Science 2026-04-01 Huynh Trinh Ngoc , Hoang Anh Nguyen Kim , Toan Nguyen Hai , Long Tran Quoc

Generating healthy counterfactuals from pathological images holds significant promise in medical imaging, e.g., in anomaly detection or for application of analysis tools that are designed for healthy scans. These counterfactuals should…

Computer Vision and Pattern Recognition · Computer Science 2025-10-16 Ana Lawry Aguila , Peirong Liu , Marina Crespo Aguirre , Juan Eugenio Iglesias

Image annotation is one essential prior step to enable data-driven algorithms. In medical imaging, having large and reliably annotated data sets is crucial to recognize various diseases robustly. However, annotator performance varies…

Image and Video Processing · Electrical Eng. & Systems 2022-11-23 Sonja Kunzmann , Mathias Öttl , Prathmesh Madhu , Felix Denzinger , Andreas Maier

Accurately identifying oocytes that progress to the blastocyst stage is crucial in reproductive medicine, but the limited availability of annotated high-quality embryo images presents challenges for developing automated diagnostic tools. To…

Quantitative Methods · Quantitative Biology 2025-06-18 Alejandro Golfe , Natalia P. García-de-la-puente , Adrián Colomer , Valery Naranjo

Medical image segmentation models struggle with rare abnormalities due to scarce annotated pathological data. We propose DiffAug a novel framework that combines textguided diffusion-based generation with automatic segmentation validation to…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Maham Nazir , Muhammad Aqeel , Francesco Setti

Denoising Diffusion Probabilistic Model (DDPM) is able to make flexible conditional image generation from prior noise to real data, by introducing an independent noise-aware classifier to provide conditional gradient guidance at each time…

Computer Vision and Pattern Recognition · Computer Science 2022-09-21 Shengming Li , Guangcong Zheng , Hui Wang , Taiping Yao , Yang Chen , Shoudong Ding , Xi Li

Deep Learning (DL) models have been successfully applied to many applications including biomedical cell segmentation and classification in histological images. These models require large amounts of annotated data which might not always be…

Image and Video Processing · Electrical Eng. & Systems 2024-06-04 Roberto Basla , Loris Giulivi , Luca Magri , Giacomo Boracchi

Denoising Diffusion Probabilistic Models (DDPMs) are powerful generative deep learning models that have been very successful at image generation, and, very recently, in path planning and control. In this paper, we investigate how to…

Robotics · Computer Science 2024-11-18 Michiel Nikken , Nicolò Botteghi , Wesley Roozing , Federico Califano

Access to high-quality datasets in the medical industry limits machine learning model performance. To address this issue, we propose a Denoising Diffusion Probabilistic Model (DDPM) combined with a UNet architecture for X-ray image…

Image and Video Processing · Electrical Eng. & Systems 2024-01-04 Praveen Mahaulpatha , Thulana Abeywardane , Tomson George

This study introduces Polyp-DDPM, a diffusion-based method for generating realistic images of polyps conditioned on masks, aimed at enhancing the segmentation of gastrointestinal (GI) tract polyps. Our approach addresses the challenges of…

Computer Vision and Pattern Recognition · Computer Science 2025-01-07 Zolnamar Dorjsembe , Hsing-Kuo Pao , Furen Xiao

Denoising diffusion probabilistic models (DDPMs) have achieved high quality image generation without adversarial training, yet they require simulating a Markov chain for many steps to produce a sample. To accelerate sampling, we present…

Machine Learning · Computer Science 2022-10-07 Jiaming Song , Chenlin Meng , Stefano Ermon

In recent years, computational pathology has seen tremendous progress driven by deep learning methods in segmentation and classification tasks aiding prognostic and diagnostic settings. Nuclei segmentation, for instance, is an important…

Image and Video Processing · Electrical Eng. & Systems 2023-03-22 Aman Shrivastava , P. Thomas Fletcher

We investigate whether synthetic images generated by diffusion models can enhance multi-label classification of protein subcellular localization. Specifically, we implement a simplified class-conditional denoising diffusion probabilistic…

Computer Vision and Pattern Recognition · Computer Science 2025-05-30 Sylvey Lin , Zhi-Yi Cao

We present a domain adaptation of video diffusion models to generate highly realistic time-lapse microscopy videos of cell division in HeLa cells. Although state-of-the-art generative video models have advanced significantly for natural…

Computer Vision and Pattern Recognition · Computer Science 2025-04-03 Alexander Holmberg , Nils Mechtel , Wei Ouyang

Denoising Diffusion Models (DDMs) have become a popular tool for generating high-quality samples from complex data distributions. These models are able to capture sophisticated patterns and structures in the data, and can generate samples…

Computer Vision and Pattern Recognition · Computer Science 2024-08-20 Emanuele Aiello , Diego Valsesia , Enrico Magli

Deep learning in cardiac MRI (CMR) is fundamentally constrained by both data scarcity and privacy regulations. This study systematically benchmarks three generative architectures: Denoising Diffusion Probabilistic Models (DDPM), Latent…

Computer Vision and Pattern Recognition · Computer Science 2026-03-05 Madhura Edirisooriya , Dasuni Kawya , Ishan Kumarasinghe , Isuri Devindi , Mary M. Maleckar , Roshan Ragel , Isuru Nawinne , Vajira Thambawita

Deep learning models in the Earth Observation domain heavily rely on the availability of large-scale accurately labeled satellite imagery. However, obtaining and labeling satellite imagery is a resource-intensive endeavor. While generative…

Computer Vision and Pattern Recognition · Computer Science 2023-10-02 Orkhan Baghirli , Hamid Askarov , Imran Ibrahimli , Ismat Bakhishov , Nabi Nabiyev

Generative modeling of 3D LiDAR data is an emerging task with promising applications for autonomous mobile robots, such as scalable simulation, scene manipulation, and sparse-to-dense completion of LiDAR point clouds. While existing…

Computer Vision and Pattern Recognition · Computer Science 2024-03-05 Kazuto Nakashima , Ryo Kurazume

Diffusion models have enabled remarkably high-quality medical image generation, yet it is challenging to enforce anatomical constraints in generated images. To this end, we propose a diffusion model-based method that supports…

Image and Video Processing · Electrical Eng. & Systems 2024-06-21 Nicholas Konz , Yuwen Chen , Haoyu Dong , Maciej A. Mazurowski

Deep generative models are key-enabling technology to computer vision, text generation, and large language models. Denoising diffusion probabilistic models (DDPMs) have recently gained much attention due to their ability to generate diverse…

Quantum Physics · Physics 2026-02-02 Bingzhi Zhang , Peng Xu , Xiaohui Chen , Quntao Zhuang