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Myocardial contrast echocardiography (MCE) is an imaging technique that assesses left ventricle function and myocardial perfusion for the detection of coronary artery diseases. Automatic MCE perfusion quantification is challenging and…

Computer Vision and Pattern Recognition · Computer Science 2018-06-21 Yuanwei Li , Chin Pang Ho , Matthieu Toulemonde , Navtej Chahal , Roxy Senior , Meng-Xing Tang

In SPECT image reconstruction, limited-angle (LA) conditions lead to a loss of frequency components, which distort the reconstructed tomographic image along directions corresponding to the non-collected projection angle range. Although…

Medical Physics · Physics 2025-07-16 Kensuke Hori , Fumio Hashimoto , Kazuya Koyama , Takeyuki Hashimoto

The Dynamic Cardiac SPECT (DC-SPECT) system is being developed at the Massachusetts General Hospital, featuring a static cardio focus asymmetrical geometry enabling simultaneous high resolution and high sensitivity imaging. Among 14 design…

Medical Physics · Physics 2023-01-02 Yuemeng Feng , William Worstell , Matthew Kupinski , Lars R Furenlid , Hamid Sabet

The compressed sensing (CS) framework leverages the sparsity of MR images to reconstruct from undersampled acquisitions. CS reconstructions involve one or more regularization parameters that weigh sparsity in transform domains against…

Focused transmits are the most commonly used transmit strategy for echocardiograms, but suffer from relatively low frame rates, and in 3D, even lower volume rates. Fast imaging based on unfocused transmits has disadvantages such as motion…

Signal Processing · Electrical Eng. & Systems 2026-05-14 Wessel L. van Nierop , Oisín Nolan , Tristan S. W. Stevens , Ruud J. G. van Sloun

Attenuation compensation (AC) is beneficial for visual interpretation tasks in single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI). However, traditional AC methods require the availability of a transmission…

Medical Physics · Physics 2023-03-21 Zitong Yu , Md Ashequr Rahman , Craig K. Abbey , Barry A. Siegel , Abhinav K. Jha

A recently proposed scatter-window and deep learning-based attenuation compensation (AC) method for myocardial perfusion imaging (MPI) by single-photon emission computed tomography (SPECT), namely CTLESS, demonstrated promising performance…

Medical Physics · Physics 2025-03-24 Zitong Yu , Nu Ri Choi , Zezhang Yang , Nancy A. Obuchowski , Barry A. Siegel , Abhinav K. Jha

Spectral imaging is a method in medical x-ray imaging to extract information about the object constituents by the material-specific energy dependence of x-ray attenuation. Contrast-enhanced spectral imaging has been thoroughly investigated,…

Medical Physics · Physics 2021-01-26 Erik Fredenberg , Magnus Aslund , Bjorn Cederstrom , Mats Lundqvist , Mats Danielsson

Myocardial pathology segmentation (MyoPS) can be a prerequisite for the accurate diagnosis and treatment planning of myocardial infarction. However, achieving this segmentation is challenging, mainly due to the inadequate and indistinct…

Image and Video Processing · Electrical Eng. & Systems 2022-11-30 Junyi Qiu , Lei Li , Sihan Wang , Ke Zhang , Yinyin Chen , Shan Yang , Xiahai Zhuang

Single Photon Emission Computed Tomography (SPECT) is one of the nuclear medicine imaging modalities used for functional analysis of animal and human organs. Gamma rays emitted from the scanned body are filtered with collimators and…

Image and Video Processing · Electrical Eng. & Systems 2020-12-15 Manu Francis , Muhammed Tarek , Mark Pickering , Murat Tahtali

Accurate segmentation and motion estimation of myocardium have always been important in clinic field, which essentially contribute to the downstream diagnosis. However, existing methods cannot always guarantee the shape integrity for…

Computer Vision and Pattern Recognition · Computer Science 2022-07-22 Xiaoling Hu , Xiao Chen , Yikang Liu , Eric Z. Chen , Terrence Chen , Shanhui Sun

In this work we explored the use of patient specific reinforced learning to generate 3D activity maps from two 2D planar images (anterior and posterior). The solution of this problem remains unachievable using conventional methodologies and…

In perioperative care, precise in-bed 3D patient pose and shape estimation (PSE) can be vital in optimizing patient positioning in preoperative planning, enabling accurate overlay of medical images for augmented reality-based surgical…

Computer Vision and Pattern Recognition · Computer Science 2026-03-19 Mingxiao Tu , Hoijoon Jung , Alireza Moghadam , Jineel Raythatha , Lachlan Allan , Jeremy Hsu , Andre Kyme , Jinman Kim

Single-Photon Emission Computed Tomography (SPECT) is widely applied for the diagnosis of coronary artery diseases. Low-dose (LD) SPECT aims to minimize radiation exposure but leads to increased image noise. Limited-view (LV) SPECT, such as…

Image and Video Processing · Electrical Eng. & Systems 2024-01-25 Xiongchao Chen , Bo Zhou , Xueqi Guo , Huidong Xie , Qiong Liu , James S. Duncan , Albert J. Sinusas , Chi Liu

Attenuation compensation (AC) is a pre-requisite for reliable quantification and beneficial for visual interpretation tasks in single-photon emission computed tomography (SPECT). Typical AC methods require the availability of an attenuation…

Medical Physics · Physics 2021-02-12 Zitong Yu , Md Ashequr Rahman , Thomas Schindler , Richard Laforest , Abhinav K. Jha

Optical stellar interferometers have demonstrated milli-arcsecond resolution with few apertures spaced hundreds of meters apart. To obtain rich direct images, many apertures will be needed, for a better sampling of the incoming wavefront.…

Instrumentation and Methods for Astrophysics · Physics 2014-09-17 Arun Surya , Swapan K. Saha , Antoine Labeyrie

In High Contrast Imaging, a large instrumental, technological and algorithmic effort is made to reduce residual speckle noise and improve the detection capabilities. In this work, we explore the potential of using a precise physical…

Instrumentation and Methods for Astrophysics · Physics 2024-02-13 Dotan Gazith , Barak Zackay

Clinical fusion of Single Photon Emission Computed Tomography Myocardial Perfusion Imaging (SPECT MPI) and Computed Tomography Angiography (CTA) remains limited by cross-modality misregistration and reliance on manual landmarks, which can…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Ni Yao , Xiangyu Liu , Shaojie Tang , Danyang Sun , Chuang Han , Yanting Li , Jiaofen Nan , Chengyang Li , Fubao Zhu , Chen Zhao , Zhihui Xu , Weihua Zhou

Photoacoustic computed tomography (PACT) is an emerging computed imaging modality that exploits optical contrast and ultrasonic detection principles to form images of the absorbed optical energy density within tissue. When the imaging…

Medical Physics · Physics 2016-11-15 Qiwei Sheng , Kun Wang , Thomas P. Matthews , Jun Xia , Liren Zhu , Lihong V. Wang , Mark A. Anastasio

The RefleXion X1 is the first biology-guided radiotherapy (BgRT) system. Its dual 90-degree PET detector collects fewer pair production events compared to a full-ring diagnostic PET system. In the proposed BgRT workflow, a short scan is…