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Deep learning models have achieved promising results in breast cancer classification, yet their 'black-box' nature raises interpretability concerns. This research addresses the crucial need to gain insights into the decision-making process…

Computer Vision and Pattern Recognition · Computer Science 2024-08-26 Ann-Kristin Balve , Peter Hendrix

Recent developments in single-cell omics technologies have enabled the quantification of molecular profiles in individual cells at an unparalleled resolution. Deep learning, a rapidly evolving sub-field of machine learning, has instilled a…

Genomics · Quantitative Biology 2024-01-17 Manoj M Wagle , Siqu Long , Carissa Chen , Chunlei Liu , Pengyi Yang

Interpretation of deep learning remains a very challenging problem. Although the Class Activation Map (CAM) is widely used to interpret deep model predictions by highlighting object location, it fails to provide insight into the salient…

Computer Vision and Pattern Recognition · Computer Science 2024-05-30 Yuguang Yang , Runtang Guo , Sheng Wu , Yimi Wang , Juan Zhang , Xuan Gong , Baochang Zhang

Unsupervised graph representation learning has recently gained interest in several application domains such as neuroscience, where modeling the diverse morphology of cell types in the brain is one of the key challenges. It is currently…

Machine Learning · Statistics 2023-07-12 Marissa A. Weis , Laura Hansel , Timo Lüddecke , Alexander S. Ecker

The convolutional neural network (CNN) has become a powerful tool for various biomedical image analysis tasks, but there is a lack of visual explanation for the machinery of CNNs. In this paper, we present a novel algorithm,…

Computer Vision and Pattern Recognition · Computer Science 2018-06-08 Guannan Zhao , Bo Zhou , Kaiwen Wang , Rui Jiang , Min Xu

How can we find interpretable, domain-appropriate models of natural phenomena given some complex, raw data such as images? Can we use such models to derive scientific insight from the data? In this paper, we propose some methods for…

Machine Learning · Computer Science 2024-02-06 Christopher J. Soelistyo , Alan R. Lowe

Recently, applying deep neural networks in IR has become an important and timely topic. For instance, Neural Ranking Models(NRMs) have shown promising performance compared to the traditional ranking models. However, explaining the ranking…

Information Retrieval · Computer Science 2020-05-13 Jaekeol Choi , Jungin Choi , Wonjong Rhee

Understanding model decisions is crucial in medical imaging, where interpretability directly impacts clinical trust and adoption. Vision Transformers (ViTs) have demonstrated state-of-the-art performance in diagnostic imaging; however,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-15 Leili Barekatain , Ben Glocker

Accurate skin disease classification is a critical yet challenging task due to high inter-class similarity, intra-class variability, and complex lesion textures. While deep learning-based computer-aided diagnosis (CAD) systems have shown…

Computer Vision and Pattern Recognition · Computer Science 2025-08-07 Enam Ahmed Taufik , Abdullah Khondoker , Antara Firoz Parsa , Seraj Al Mahmud Mostafa

Deep learning opacity often impedes deployment in high-stakes domains. We propose a training framework that aligns model focus with class-representative features without requiring pixel-level annotations. To this end, we introduce…

Artificial Intelligence · Computer Science 2026-02-16 Giacomo Ignesti , Davide Moroni , Massimo Martinelli

The visual attributes of cells, such as the nuclear morphology and chromatin openness, are critical for histopathology image analysis. By learning cell-level visual representation, we can obtain a rich mix of features that are highly…

Computer Vision and Pattern Recognition · Computer Science 2018-07-10 Bo Hu , Ye Tang , Eric I-Chao Chang , Yubo Fan , Maode Lai , Yan Xu

Microscopy images contain rich information about how cells respond to perturbations, making them essential to applications like drug screening. To quantify images, researchers often use representation extraction methods, and recent years…

Computer Vision and Pattern Recognition · Computer Science 2026-05-18 Emre Hayir , Lorin Crawford , Alex X. Lu

Decisions made by convolutional neural networks(CNN) can be understood and explained by visualizing discriminative regions on images. To this end, Class Activation Map (CAM) based methods were proposed as powerful interpretation tools,…

Computer Vision and Pattern Recognition · Computer Science 2023-07-12 Yi Liao , Yongsheng Gao , Weichuan Zhang

Current weakly supervised object localization and segmentation rely on class-discriminative visualization techniques to generate pseudo-labels for pixel-level training. Such visualization methods, including class activation mapping (CAM)…

Computer Vision and Pattern Recognition · Computer Science 2020-10-20 Xiangwei Shi , Seyran Khademi , Yunqiang Li , Jan van Gemert

While deep learning has been successfully applied to the data-driven classification of anomalous diffusion mechanisms, how the algorithm achieves the feat still remains a mystery. In this study, we use a well-known technique aimed at…

Machine Learning · Computer Science 2024-10-23 Jaeyong Bae , Yongjoo Baek , Hawoong Jeong

Deep neural networks are ubiquitous due to the ease of developing models and their influence on other domains. At the heart of this progress is convolutional neural networks (CNNs) that are capable of learning representations or features…

Computer Vision and Pattern Recognition · Computer Science 2020-10-26 Mohammed Bany Muhammad , Mohammed Yeasin

Multimodal representation learning has shown promising improvements on various vision-language tasks. Most existing methods excel at building global-level alignment between vision and language while lacking effective fine-grained image-text…

Computer Vision and Pattern Recognition · Computer Science 2023-06-16 Zijia Zhao , Longteng Guo , Xingjian He , Shuai Shao , Zehuan Yuan , Jing Liu

Gradient-weighted Class Activation Mapping (Grad- CAM), is an example-based explanation method that provides a gradient activation heat map as an explanation for Convolution Neural Network (CNN) models. The drawback of this method is that…

Computer Vision and Pattern Recognition · Computer Science 2022-04-13 Tanmay Chakraborty , Utkarsh Trehan , Khawla Mallat , Jean-Luc Dugelay

Deep learning based medical image classifiers have shown remarkable prowess in various application areas like ophthalmology, dermatology, pathology, and radiology. However, the acceptance of these Computer-Aided Diagnosis (CAD) systems in…

Compared with expensive pixel-wise annotations, image-level labels make it possible to learn semantic segmentation in a weakly-supervised manner. Within this pipeline, the class activation map (CAM) is obtained and further processed to…

Computer Vision and Pattern Recognition · Computer Science 2022-01-06 Jiawei Liu , Jing Zhang , Yicong Hong , Nick Barnes