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Problem definition: Personalized medicine (PM) seeks the best treatment for each patient among a set of available treatment methods. Since a specific treatment does not work well on all patients, traditionally, the best treatment was…

Optimization and Control · Mathematics 2023-08-03 Jianzhong Du , Siyang Gao , Chun-Hung Chen

For personalized ranking models, the well-calibrated probability of an item being preferred by a user has great practical value. While existing work shows promising results in image classification, probability calibration has not been much…

Information Retrieval · Computer Science 2022-04-27 Wonbin Kweon , SeongKu Kang , Hwanjo Yu

Machine learning algorithms are increasingly used to inform critical decisions. There is a growing concern about bias, that algorithms may produce uneven outcomes for individuals in different demographic groups. In this work, we measure…

Machine Learning · Computer Science 2021-06-01 Runshan Fu , Yangfan Liang , Peter Zhang

Objective: ML-based clinical risk prediction models are increasingly used to support decision-making in healthcare. While class-imbalance correction techniques are commonly applied to improve model performance in settings with rare…

The problem of model selection is inevitable in an increasingly large number of applications involving partial theoretical knowledge and vast amounts of information, like in medicine, biology or economics. The associated techniques are…

Methodology · Statistics 2015-11-17 Stephane Guerrier , Maria-Pia Victoria-Feser

Calibrating deep neural models plays an important role in building reliable, robust AI systems in safety-critical applications. Recent work has shown that modern neural networks that possess high predictive capability are poorly calibrated…

Machine Learning · Computer Science 2025-09-16 Cheng Wang

Probabilistic classifiers output a probability distribution on target classes rather than just a class prediction. Besides providing a clear separation of prediction and decision making, the main advantage of probabilistic models is their…

Machine Learning · Computer Science 2019-02-20 Juozas Vaicenavicius , David Widmann , Carl Andersson , Fredrik Lindsten , Jacob Roll , Thomas B. Schön

Aligning large language models (LLMs) with human preferences has been recognized as the key to improving LLMs' interaction quality. However, in this pluralistic world, human preferences can be diversified due to annotators' different…

Artificial Intelligence · Computer Science 2024-10-08 Dun Zeng , Yong Dai , Pengyu Cheng , Longyue Wang , Tianhao Hu , Wanshun Chen , Nan Du , Zenglin Xu

With ever-increasing amounts of online information available, modeling and predicting individual preferences-for books or articles, for example-is becoming more and more important. Good predictions enable us to improve advice to users, and…

Social and Information Networks · Computer Science 2017-02-06 Antonia Godoy-Lorite , Roger Guimera , Cristopher Moore , Marta Sales-Pardo

Trust calibration is necessary to ensure appropriate user acceptance in advanced automation technologies. A significant challenge to achieve trust calibration is to quantitatively estimate human trust in real-time. Although multiple trust…

Human-Computer Interaction · Computer Science 2023-04-17 Jundi Liu , Kumar Akash , Teruhisa Misu , Xingwei Wu

We propose a method to optimize language model pre-training data mixtures through efficient approximation of the cross-entropy loss corresponding to each candidate mixture via a Mixture of Data Experts (MDE). We use this approximation as a…

Machine Learning · Computer Science 2025-02-25 Lior Belenki , Alekh Agarwal , Tianze Shi , Kristina Toutanova

Federated learning has received significant attention for its ability to simultaneously protect customer privacy and leverage distributed data from multiple devices for model training. However, conventional approaches often focus on…

Machine Learning · Computer Science 2025-10-07 Jiahao Zeng , Wolong Xing , Liangtao Shi , Xin Huang , Jialin Wang , Zhile Cao , Zhenkui Shi

Traditional statistical and machine learning methods typically assume that the training and test data follow the same distribution. However, this assumption is frequently violated in real-world applications, where the training data in the…

Methodology · Statistics 2025-07-08 Hanxuan Ye , Hongzhe Li

In an increasing number of applications designers have access to multiple computer models which typically have different levels of fidelity and cost. Traditionally, designers calibrate these models one at a time against some high-fidelity…

Machine Learning · Computer Science 2025-06-02 Jonathan Tammer Eweis-Labolle , Tyler Johnson , Xiangyu Sun , Ramin Bostanabad

We introduce a new multiple type I error criterion for clinical trials with multiple populations. Such trials are of interest in precision medicine where the goal is to develop treatments that are targeted to specific sub-populations…

Methodology · Statistics 2021-02-05 Werner Brannath , Charlie Hillner , Kornelius Rohmeyer

The understanding of complex physical or biological systems nearly always requires a characterisation of the variability that underpins these processes. In addition, the data used to calibrate such models may also often exhibit considerable…

Tissues and Organs · Quantitative Biology 2017-06-22 Brodie A. J. Lawson , Christopher C. Drovandi , Nicole Cusimano , Pamela Burrage , Blanca Rodriguez , Kevin Burrage

Large Language Models (LLMs) have recently emerged as planners for language-instructed agents, generating sequences of actions to accomplish natural language tasks. However, their reliability remains a challenge, especially in long-horizon…

Robotics · Computer Science 2025-11-11 Jun Wang , Yevgeniy Vorobeychik , Yiannis Kantaros

We consider a finite mixture of regressions (FMR) model for high-dimensional inhomogeneous data where the number of covariates may be much larger than sample size. We propose an l1-penalized maximum likelihood estimator in an appropriate…

Methodology · Statistics 2012-02-28 Nicolas Städler , Peter Bühlmann , Sara van de Geer

Though machine learning algorithms excel at minimizing the average loss over a population, this might lead to large discrepancies between the losses across groups within the population. To capture this inequality, we introduce and study a…

Machine Learning · Computer Science 2019-06-11 Fereshte Khani , Aditi Raghunathan , Percy Liang

This study presents a semi-nonparametric Latent Class Choice Model (LCCM) with a flexible class membership component. The proposed model formulates the latent classes using mixture models as an alternative approach to the traditional random…