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For data with high-dimensional covariates but small to moderate sample sizes, the analysis of single datasets often generates unsatisfactory results. The integrative analysis of multiple independent datasets provides an effective way of…

Methodology · Statistics 2015-01-19 Yuan Huang , Qingzhao Zhang , Sanguo Zhang , Jian Huang , Shuangge Ma

Count data analysis is essential across diverse fields, from ecology and accident analysis to single-cell RNA sequencing (scRNA-seq) and metagenomics. While log transformations are computationally efficient, model-based approaches such as…

Methodology · Statistics 2024-11-14 Bastien Batardière , Julien Chiquet , Mahendra Mariadassou

Multivariate count models are often justified by their ability to capture latent dependence, but researchers receive little guidance on when this added structure improves on simpler penalized marginal Poisson regression. We study this…

Machine Learning · Computer Science 2026-04-07 Daniel Agyapong , Julien Chiquet , Jane Marks , Toby Dylan Hocking

Sparsity-inducing penalties are useful tools for variable selection and they are also effective for regression settings where the data are functions. We consider the problem of selecting not only variables but also decision boundaries in…

Methodology · Statistics 2020-06-01 Hidetoshi Matsui

Modern variable selection procedures make use of penalization methods to execute simultaneous model selection and estimation. A popular method is the LASSO (least absolute shrinkage and selection operator), the use of which requires…

Methodology · Statistics 2023-01-12 Meadhbh O'Neill , Kevin Burke

The Poisson log-normal model is a latent variable model that provides a generic framework for the analysis of multivariate count data. Inferring its parameters can be a daunting task since the conditional distribution of the latent…

Computation · Statistics 2026-05-19 Julien Stoehr , Stephane S. Robin

We proposed a new penalized method in this paper to solve sparse Poisson Regression problems. Being different from $\ell_1$ penalized log-likelihood estimation, our new method can be viewed as penalized weighted score function method. We…

Statistics Theory · Mathematics 2017-03-14 Jinzhu Jia , Fang Xie , Lihu Xu

Modeling data with multivariate count responses is a challenging problem due to the discrete nature of the responses. Existing methods for univariate count responses cannot be easily extended to the multivariate case since the dependency…

Methodology · Statistics 2016-08-15 Hao Wu , Xinwei Deng , Naren Ramakrishnan

Sparse covariates are frequent in classification and regression problems and in these settings the task of variable selection is usually of interest. As it is well known, sparse statistical models correspond to situations where there are…

Methodology · Statistics 2020-02-14 Ana M. Bianco , Graciela Boente , Gonzalo Chebi

We consider the problem of sparse estimation via a lasso-type penalized likelihood procedure in a factor analysis model. Typically, the model estimation is done under the assumption that the common factors are orthogonal (uncorrelated).…

Methodology · Statistics 2013-02-25 Kei Hirose , Michio Yamamoto

We consider the problem of estimating the parameters of a Gaussian or binary distribution in such a way that the resulting undirected graphical model is sparse. Our approach is to solve a maximum likelihood problem with an added l_1-norm…

Artificial Intelligence · Computer Science 2007-07-06 Onureena Banerjee , Laurent El Ghaoui , Alexandre d'Aspremont

Molecular profiling data (e.g., gene expression) has been used for clinical risk prediction and biomarker discovery. However, it is necessary to integrate other prior knowledge like biological pathways or gene interaction networks to…

Genomics · Quantitative Biology 2016-09-22 Wenwen Min , Juan Liu , Shihua Zhang

Sparse estimation methods are aimed at using or obtaining parsimonious representations of data or models. They were first dedicated to linear variable selection but numerous extensions have now emerged such as structured sparsity or kernel…

Machine Learning · Computer Science 2011-11-24 Francis Bach , Rodolphe Jenatton , Julien Mairal , Guillaume Obozinski

When studying ecosystems, hierarchical trees are often used to organize entities based on proximity criteria, such as the taxonomy in microbiology, social classes in geography, or product types in retail businesses, offering valuable…

Methodology · Statistics 2025-06-27 Alexandre Chaussard , Anna Bonnet , Elisabeth Gassiat , Sylvain Le Corff

Recently, there has been focus on penalized log-likelihood covariance estimation for sparse inverse covariance (precision) matrices. The penalty is responsible for inducing sparsity, and a very common choice is the convex $l_1$ norm.…

Machine Learning · Statistics 2023-07-19 Goran Marjanovic , Alfred O. Hero

We consider a problem of model selection in high-dimensional binary Markov random fields. The usefulness of the Ising model in studying systems of complex interactions has been confirmed in many papers. The main drawback of this model is…

Methodology · Statistics 2018-12-11 Błażej Miasojedow , Wojciech Rejchel

Multiple systems estimation strategies have recently been applied to quantify hard-to-reach populations, particularly when estimating the number of victims of human trafficking and modern slavery. In such contexts, it is not uncommon to see…

Methodology · Statistics 2020-03-06 Lax Chan , Bernard W. Silverman , Kyle Vincent

The pseudo-likelihood method is one of the most popular algorithms for learning sparse binary pairwise Markov networks. In this paper, we formulate the $L_1$ regularized pseudo-likelihood problem as a sparse multiple logistic regression…

Machine Learning · Statistics 2017-04-10 Sinong Geng , Zhaobin Kuang , David Page

High-dimensional count data poses significant challenges for statistical analysis, necessitating effective methods that also preserve explainability. We focus on a low rank constrained variant of the Poisson log-normal model, which relates…

Optimization and Control · Mathematics 2025-06-17 Bastien Batardière , Julien Chiquet , Joon Kwon , Julien Stoehr

We consider the problem of variable selection in varying-coefficient functional linear models, where multiple predictors are functions and a response is a scalar and depends on an exogenous variable. The varying-coefficient functional…

Methodology · Statistics 2021-10-26 Hidetoshi Matsui
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