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High-speed optical imaging of dynamic neuronal activity is essential yet challenging in neuroscience. While calcium imaging has been firmly established as a workhorse technique for monitoring neuronal activity, its limited temporal…

Reconstruction of neuroanatomy is a fundamental problem in neuroscience. Stochastic expression of colors in individual cells is a promising tool, although its use in the nervous system has been limited due to various sources of variability…

Neurons and Cognition · Quantitative Biology 2017-01-24 Uygar Sümbül , Douglas Roussien , Fei Chen , Nicholas Barry , Edward S. Boyden , Dawen Cai , John P. Cunningham , Liam Paninski

Advances in optical neuroimaging techniques now allow neural activity to be recorded with cellular resolution in awake and behaving animals. Brain motion in these recordings pose a unique challenge. The location of individual neurons must…

Neurons and Cognition · Quantitative Biology 2017-05-22 Jeffrey P. Nguyen , Ashley N. Linder , George S. Plummer , Joshua W. Shaevitz , Andrew M. Leifer

The automated analysis of microscopy images is a challenge in the context of single-cell tracking and quantification. This work has as goals the study of the performance of deep learning for segmenting microscopy images and the improvement…

Quantitative Methods · Quantitative Biology 2022-10-05 André O. Françani

NeuroNet is a deep convolutional neural network mimicking multiple popular and state-of-the-art brain segmentation tools including FSL, SPM, and MALPEM. The network is trained on 5,000 T1-weighted brain MRI scans from the UK Biobank Imaging…

Computer Vision and Pattern Recognition · Computer Science 2018-06-13 Martin Rajchl , Nick Pawlowski , Daniel Rueckert , Paul M. Matthews , Ben Glocker

In interventional radiology, short video sequences of vein structure in motion are captured in order to help medical personnel identify vascular issues or plan intervention. Semantic segmentation can greatly improve the usefulness of these…

Computer Vision and Pattern Recognition · Computer Science 2018-08-06 Athanasios Vlontzos , Krystian Mikolajczyk

Fluorescence microscopy is widely employed for the analysis of living biological samples; however, the utility of the resulting recordings is frequently constrained by noise, temporal variability, and inconsistent visualisation of signals…

Computer Vision and Pattern Recognition · Computer Science 2026-01-16 Hassan Eshkiki , Sarah Costa , Mostafa Mohammadpour , Farinaz Tanhaei , Christopher H. George , Fabio Caraffini

This paper tackles the problem of real-time semantic segmentation of high definition videos using a hybrid GPU / CPU approach. We propose an Efficient Video Segmentation(EVS) pipeline that combines: (i) On the CPU, a very fast optical flow…

Computer Vision and Pattern Recognition · Computer Science 2019-12-30 Matthieu Paul , Christoph Mayer , Luc Van Gool , Radu Timofte

Though performed almost effortlessly by humans, segmenting 2D gray-scale or color images into respective regions of interest (e.g.~background, objects, or portions of objects) constitutes one of the greatest challenges in science and…

Computer Vision and Pattern Recognition · Computer Science 2023-08-23 Alexandre Benatti , Luciano da F. Costa

We present a method for segmenting neuron membranes in 2D electron microscopy imagery. This segmentation task has been a bottleneck to reconstruction efforts of the brain's synaptic circuits. One common problem is the misclassification of…

Computer Vision and Pattern Recognition · Computer Science 2020-02-05 Thanuja D. Ambegoda , Matthew Cook

Endoscopic surgery is currently an important treatment method in the field of spinal surgery and avoiding damage to the spinal nerves through video guidance is a key challenge. This paper presents the first real-time segmentation method for…

Computer Vision and Pattern Recognition · Computer Science 2023-07-21 Shaowu Peng , Pengcheng Zhao , Yongyu Ye , Junying Chen , Yunbing Chang , Xiaoqing Zheng

The development of voltage-sensitive fluorescent probes suggests fluorescence lifetime as a promising readout for electrical activity in biological systems. Existing approaches fail to achieve the speed and sensitivity required for voltage…

Optics · Physics 2023-06-27 Adam J. Bowman , Cheng Huang , Mark J. Schnitzer , Mark A. Kasevich

Automatic segmentation of neuronal topology is critical for handling large scale neuroimaging data, as it can greatly accelerate neuron annotation and analysis. However, the intricate morphology of neuronal branches and the occlusions among…

Image and Video Processing · Electrical Eng. & Systems 2025-08-01 Huayu Fu , Jiamin Li , Haozhi Qu , Xiaolin Hu , Zengcai Guo

The field of connectomics faces unprecedented "big data" challenges. To reconstruct neuronal connectivity, automated pixel-level segmentation is required for petabytes of streaming electron microscopy data. Existing algorithms provide…

Motivation: 3D neuron segmentation is a key step for the neuron digital reconstruction, which is essential for exploring brain circuits and understanding brain functions. However, the fine line-shaped nerve fibers of neuron could spread in…

Image and Video Processing · Electrical Eng. & Systems 2021-11-09 Qiufu Li , Linlin Shen

Registration is a fundamental task in medical image analysis which can be applied to several tasks including image segmentation, intra-operative tracking, multi-modal image alignment, and motion analysis. Popular registration tools such as…

Computer Vision and Pattern Recognition · Computer Science 2019-10-07 Wentao Zhu , Andriy Myronenko , Ziyue Xu , Wenqi Li , Holger Roth , Yufang Huang , Fausto Milletari , Daguang Xu

Modern imaging techniques for probing brain function, including functional Magnetic Resonance Imaging, intrinsic and extrinsic contrast optical imaging, and magnetoencephalography, generate large data sets with complex content. In this…

Neurons and Cognition · Quantitative Biology 2009-11-10 P. P. Mitra , B. Pesaran

Real-time rendering for video games has become increasingly challenging due to the need for higher resolutions, framerates and photorealism. Supersampling has emerged as an effective solution to address this challenge. Our work introduces a…

Computer Vision and Pattern Recognition · Computer Science 2023-08-04 Antoine Mercier , Ruan Erasmus , Yashesh Savani , Manik Dhingra , Fatih Porikli , Guillaume Berger

State-of-the-art systems for semantic image segmentation use feed-forward pipelines with fixed computational costs. Building an image segmentation system that works across a range of computational budgets is challenging and time-intensive…

Computer Vision and Pattern Recognition · Computer Science 2018-03-16 Lane McIntosh , Niru Maheswaranathan , David Sussillo , Jonathon Shlens

Segmenting the retinal vasculature entails a trade-off between how much of the overall vascular structure we identify vs. how precisely we segment individual vessels. In particular, state-of-the-art methods tend to under-segment faint…

Computer Vision and Pattern Recognition · Computer Science 2019-03-28 Aashis Khanal , Rolando Estrada
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