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In this paper, we present a decision support framework for optimizing multiple aspects of vaccine distribution across a multitier cold chain network. We propose two multi-period optimization formulations within this framework: first to…

Physics and Society · Physics 2022-01-12 Shanmukhi Sripada , Ayush Jain , Prasanna Ramamoorthy , Varun Ramamohan

Vaccines play a crucial role in the prevention and control of infectious diseases. However, the vaccine supply chain faces numerous challenges that hinder its efficiency. To address these challenges and enhance public health outcomes, many…

Theoretical Economics · Economics 2025-10-07 Ran Gu , Enhui Ding , Shigui Ma

During various stages of the COVID-19 pandemic, countries implemented diverse vaccine management approaches, influenced by variations in infrastructure and socio-economic conditions. This article provides a comprehensive overview of…

Optimization and Control · Mathematics 2024-05-27 Shibshankar Dey , Ali Kaan Kurbanzade , Esma S. Gel , Joseph Mihaljevic , Sanjay Mehrotra

In this study, a vaccine supply chain model is developed considering the humanitarian aspects under uncertain conditions in Iran. There are three main components to supply the required vaccines for vaccination centers that can be designed…

Optimization and Control · Mathematics 2022-08-30 Behnam Malmir , Christopher W. Zobel

Supply chain resilience analysis aims to identify the critical elements in the supply chain, measure its reliability, and analyze solutions for improving vulnerabilities. While extensive methods like stochastic approaches have been…

Risk Management · Quantitative Finance 2024-05-22 Yaxin Pang , Shenle Pan , Eric Ballot

This paper is concerned with portfolio optimization models for creating high-quality lists of recommended items to balance the accuracy and diversity of recommendations. However, the statistics (i.e., expectation and covariance of ratings)…

Information Retrieval · Computer Science 2024-10-01 Tomoya Yanagi , Shunnosuke Ikeda , Yuichi Takano

In this paper, we solve the multiple product price optimization problem under interval uncertainties of the price sensitivity parameters in the demand function. The objective of the price optimization problem is to maximize the overall…

Optimization and Control · Mathematics 2021-07-01 Mahdi Hamzeei , Alvin Lim , Jiefeng Xu

Bayesian optimization is a popular tool for data-efficient optimization of expensive objective functions. In real-life applications like engineering design, the designer often wants to take multiple objectives as well as input uncertainty…

Artificial Intelligence · Computer Science 2022-02-28 J. Qing , I. Couckuyt , T. Dhaene

Mathematical models simulate various events under different conditions, enabling an early overview of the system to be implemented in practice, reducing the waste of resources and in less time. In project optimization, these models play a…

Optimization and Control · Mathematics 2021-05-11 Gustavo Barbosa Libotte , Fran Sérgio Lobato , Francisco Duarte Moura Neto , Gustavo Mendes Platt

In this paper, we consider an adaptive approach to address optimization problems with uncertain cost parameters. Here, the decision maker selects an initial decision, observes the realization of the uncertain cost parameters, and then is…

Computational Complexity · Computer Science 2013-12-17 Ebrahim Nasrabadi , James B. Orlin

In this work, we propose a robust optimization approach to mitigate the impact of uncertainties in particle precipitation. Our model incorporates partial differential equations, more particular nonlinear and nonlocal population balance…

Optimization and Control · Mathematics 2023-08-03 Martina Kuchlbauer , Jana Dienstbier , Adeel Muneer , Hanna Hedges , Michael Stingl , Frauke Liers , Lukas Pflug

Real-world problems typically require the simultaneous optimization of several, often conflicting objectives. Many of these multi-objective optimization problems are characterized by wide ranges of uncertainties in their decision variables…

Neural and Evolutionary Computing · Computer Science 2019-10-21 Faramarz Khosravi , Alexander Raß , Jürgen Teich

The field of portfolio selection is an active research topic, which combines elements and methodologies from various fields, such as optimization, decision analysis, risk management, data science, forecasting, etc. The modeling and…

Portfolio Management · Quantitative Finance 2020-10-28 A. Georgantas

We consider a combined problem of teaming and scheduling of multi-skilled employees that have to perform jobs with uncertain qualification requirements. We propose two modeling approaches that generate solutions that are robust to possible…

Optimization and Control · Mathematics 2020-11-03 Yulia Anoshkina , Marc Goerigk , Frank Meisel

How to ensure accessibility to food and nutrition while food supply chains suffer from demand and supply uncertainties caused by disruptive forces such as the COVID-19 pandemic and natural disasters is an emerging and critical issue.…

General Economics · Economics 2024-06-14 Mengfei Chen , Mohamed Kharbeche , Mohamed Haouari , Weihong "Grace" Guo

This work proposes a framework for multistage adjustable robust optimization that unifies the treatment of three different types of endogenous uncertainty, where decisions, respectively, (i) alter the uncertainty set, (ii) affect the…

Optimization and Control · Mathematics 2020-08-31 Qi Zhang , Wei Feng

Robust optimization(RO) is an important tool for handling optimization problem with uncertainty. The main objective of RO is to solve optimization problems due to uncertainty associated with constraints satisfying all realizations of…

Optimization and Control · Mathematics 2025-04-02 Parthasarathi Mondal , Akshay Kumar Ojha

Robust optimization is a method for optimization under uncertainties in engineering systems and designs for applications ranging from aeronautics to nuclear. In a robust design process, parameter variability (or uncertainty) is incorporated…

Computation · Statistics 2022-10-17 Richa Verma , Dinesh Kumar , Kazuma Kobayashi , Syed Alam

This paper delves into the challenging issues in uncertain multi-objective optimization, where uncertainty permeates nonsmooth nonconvex objective and constraint functions. In this context, we investigate highly robust (weakly efficient)…

Optimization and Control · Mathematics 2025-01-14 Morteza Rahimi , Majid Soleimani-damaneh

In this paper we examine multi-objective linear programming problems in the face of data uncertainty both in the objective function and the constraints. First, we derive a formula for radius of robust feasibility guaranteeing constraint…

Optimization and Control · Mathematics 2014-02-14 M. A. Goberna , V. Jeyakumar , G. Li , J. Vicente-Pérez
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