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Motivation Protein fold recognition is an important problem in structural bioinformatics. Almost all traditional fold recognition methods use sequence (homology) comparison to indirectly predict the fold of a tar get protein based on the…
Transrectal biopsies under 2D ultrasound (US) control are the current clinical standard for prostate cancer diagnosis. The isoechogenic nature of prostate carcinoma makes it necessary to sample the gland systematically, resulting in a low…
Medical imaging based prostate cancer diagnosis procedure uses intra-operative transrectal ultrasound (TRUS) imaging to visualize the prostate shape and location to collect tissue samples. Correct tissue sampling from prostate requires…
Identifying polyps is challenging for automatic analysis of endoscopic images in computer-aided clinical support systems. Models based on convolutional networks (CNN), transformers, and their combinations have been proposed to segment…
Precise and real-time detection of gastrointestinal polyps during endoscopic procedures is crucial for early diagnosis and prevention of colorectal cancer. This work presents EndoSight AI, a deep learning architecture developed and…
Precise segmentation of bladder walls and tumor regions is an essential step towards non-invasive identification of tumor stage and grade, which is critical for treatment decision and prognosis of patients with bladder cancer (BC). However,…
The accurate segmentation of medical images is a crucial step in obtaining reliable morphological statistics. However, training a deep neural network for this task requires a large amount of labeled data to ensure high-accuracy results. To…
Early diagnosis and accurate identification of lesion location and progression in prostate cancer (PCa) are critical for assisting clinicians in formulating effective treatment strategies. However, due to the high semantic homogeneity…
Automatic segmentation of medical images with DL algorithms has proven to be highly successful. With most of these algorithms, inter-observer variation is an acknowledged problem, leading to sub-optimal results. This problem is even more…
Colonoscopy is a gold standard procedure but is highly operator-dependent. Automated polyp segmentation, a precancerous precursor, can minimize missed rates and timely treatment of colon cancer at an early stage. Even though there are deep…
Accurate delineation of kidney tumours in Computed Tomography (CT) is essential for downstream quantitative analysis and precision oncology, but manual segmentation is a specialised task, time-consuming and difficult to scale. Automated 3D…
Breast ultrasound imaging is a valuable tool for early breast cancer detection, but automated tumor segmentation is challenging due to inherent noise, variations in scale of lesions, and fuzzy boundaries. To address these challenges, we…
A new machine learning methodology, called successive subspace learning (SSL), is introduced in this work. SSL contains four key ingredients: 1) successive near-to-far neighborhood expansion; 2) unsupervised dimension reduction via subspace…
Automatic CT segmentation of proximal femur is crucial for the diagnosis and risk stratification of orthopedic diseases; however, current methods for the femur CT segmentation mainly rely on manual interactive segmentation, which is…
The task of automatically segmenting 3-D surfaces representing boundaries of objects is important for quantitative analysis of volumetric images, and plays a vital role in biomedical image analysis. Recently, graph-based methods with a…
Model generalization capacity at domain shift (e.g., various imaging protocols and scanners) is crucial for deep learning methods in real-world clinical deployment. This paper tackles the challenging problem of domain generalization, i.e.,…
Image segmentation is a primary task in many medical applications. Recently, many deep networks derived from U-Net have been extensively used in various medical image segmentation tasks. However, in most of the cases, networks similar to…
Prostate cancer is the most dangerous cancer diagnosed in men worldwide. Prostate diagnosis has been affected by many factors, such as lesion complexity, observer visibility, and variability. Many techniques based on Magnetic Resonance…
Purpose: Ultrasound is the most commonly used medical imaging modality for diagnosis and screening in clinical practice. Due to its safety profile, noninvasive nature and portability, ultrasound is the primary imaging modality for fetal…
3D image segmentation is one of the most important and ubiquitous problems in medical image processing. It provides detailed quantitative analysis for accurate disease diagnosis, abnormal detection, and classification. Currently deep…