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The advancement of large language models (LLMs) has demonstrated strong capabilities across various applications, including mental health analysis. However, existing studies have focused on predictive performance, leaving the critical issue…

Computation and Language · Computer Science 2024-06-21 Yuqing Wang , Yun Zhao , Sara Alessandra Keller , Anne de Hond , Marieke M. van Buchem , Malvika Pillai , Tina Hernandez-Boussard

Background: As large language models (LLMs) are increasingly used in healthcare and medical consultation settings, a growing concern is whether these models can respond to medical inquiries in a manner that is ethically…

Computers and Society · Computer Science 2026-02-02 Hanhui Xu , Jiacheng Ji , Haoan Jin , Han Ying , Mengyue Wu

Recently, Large Language Models (LLM) have demonstrated impressive capability to solve a wide range of tasks. However, despite their success across various tasks, no prior work has investigated their capability in the biomedical domain yet.…

Computation and Language · Computer Science 2024-02-21 Israt Jahan , Md Tahmid Rahman Laskar , Chun Peng , Jimmy Huang

Textual data from social platforms captures various aspects of mental health through discussions around and across issues, while users reach out for help and others sympathize and offer support. We propose a comprehensive framework that…

Social and Information Networks · Computer Science 2025-03-04 Vaishali Aggarwal , Sachin Thukral , Krushil Patel , Arnab Chatterjee

Thematic analysis provides valuable insights into participants' experiences through coding and theme development, but its resource-intensive nature limits its use in large healthcare studies. Large language models (LLMs) can analyze text at…

Despite substantial progress in healthcare applications driven by large language models (LLMs), growing concerns around data privacy, and limited resources; the small language models (SLMs) offer a scalable and clinically viable solution…

Computation and Language · Computer Science 2025-04-28 Muskan Garg , Shaina Raza , Shebuti Rayana , Xingyi Liu , Sunghwan Sohn

Large Language Models (LLMs) excel in handling general knowledge tasks, yet they struggle with user-specific personalization, such as understanding individual emotions, writing styles, and preferences. Personalized Large Language Models…

Artificial Intelligence · Computer Science 2025-09-23 Jiahong Liu , Zexuan Qiu , Zhongyang Li , Quanyu Dai , Wenhao Yu , Jieming Zhu , Minda Hu , Menglin Yang , Tat-Seng Chua , Irwin King

MLLMs have recently become a focal point in the field of artificial intelligence research. Building on the strong capabilities of LLMs, MLLMs are adept at addressing complex multi-modal tasks. With the release of GPT-4, MLLMs have gained…

Machine Learning · Computer Science 2025-05-01 Jiarui Ye , Hao Tang

Objectives: To evaluate the current limitations of large language models (LLMs) in medical question answering, focusing on the quality of datasets used for their evaluation. Materials and Methods: Widely-used benchmark datasets, including…

Computation and Language · Computer Science 2025-07-15 Mahmoud Alwakeel , Aditya Nagori , Vijay Krishnamoorthy , Rishikesan Kamaleswaran

Contemporary large language models (LLMs) may have utility for processing unstructured, narrative free-text clinical data contained in electronic health records (EHRs) -- a particularly important use-case for mental health where a majority…

Artificial Intelligence · Computer Science 2024-04-01 Niall Taylor , Andrey Kormilitzin , Isabelle Lorge , Alejo Nevado-Holgado , Dan W Joyce

Large language models (LLMs) have emerged as transformative tools in medicine, with strong capabilities in language understanding, reasoning, and structured information extraction. Radiation oncology is particularly well suited for LLM…

Large Language Models (LLMs) have demonstrated exceptional capabilities in solving various tasks, progressively evolving into general-purpose assistants. The increasing integration of LLMs into society has sparked interest in whether they…

Computation and Language · Computer Science 2025-10-20 Yuan Li , Yue Huang , Hongyi Wang , Ying Cheng , Xiangliang Zhang , James Zou , Lichao Sun

Large language models (LLMs) are increasingly utilized in healthcare applications. However, their deployment in clinical practice raises significant safety concerns, including the potential spread of harmful information. This study…

Cryptography and Security · Computer Science 2025-03-05 Hang Zhang , Qian Lou , Yanshan Wang

Large Language Models (LLMs) are increasingly deployed in mental health contexts, from structured therapeutic support tools to informal chat-based well-being assistants. While these systems increase accessibility, scalability, and…

Human-Computer Interaction · Computer Science 2025-10-14 Soraya S. Anvari , Rina R. Wehbe

Large language models (LLMs) have been actively applied in the mental health field. Recent research shows the promise of LLMs in applying psychotherapy, especially motivational interviewing (MI). However, there is a lack of studies…

Computation and Language · Computer Science 2025-04-01 Haein Kong , Seonghyeon Moon

The advancement of large language models (LLMs) has outpaced traditional evaluation methodologies. This progress presents novel challenges, such as measuring human-like psychological constructs, moving beyond static and task-specific…

Computation and Language · Computer Science 2026-03-12 Haoran Ye , Jing Jin , Yuhang Xie , Xin Zhang , Guojie Song

Large Language Models (LLMs) are increasingly deployed in high-stakes domains such as clinical decision support and medical documentation. However, the robustness of these models against subtle linguistic variations, specifically…

Computation and Language · Computer Science 2026-05-19 Jen-tse Huang , Didi Zhou , Faith Kamau , Amy Oh , Anne R. Links , Mark Dredze , Mary Catherine Beach , Somnath Saha

The rapid advancement of Large Language Models (LLMs), reasoning models, and agentic AI approaches coincides with a growing global mental health crisis, where increasing demand has not translated into adequate access to professional…

Human-Computer Interaction · Computer Science 2025-04-03 Kellie Yu Hui Sim , Kenny Tsu Wei Choo

Mental health in children and adolescents has been steadily deteriorating over the past few years. The recent advent of Large Language Models (LLMs) offers much hope for cost and time efficient scaling of monitoring and intervention, yet…

Computation and Language · Computer Science 2024-04-29 Isabelle Lorge , Dan W. Joyce , Andrey Kormilitzin

Widespread stigma, both in the offline and online spaces, acts as a barrier to harm reduction efforts in the context of opioid use disorder (OUD). This stigma is prominently directed towards clinically approved medications for addiction…

Social and Information Networks · Computer Science 2025-04-16 Shravika Mittal , Darshi Shah , Shin Won Do , Mai ElSherief , Tanushree Mitra , Munmun De Choudhury