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We investigated frictional effects on the folding rates of a human telomerase hairpin (hTR HP) and H-type pseudoknot from the Beet Western Yellow Virus (BWYV PK) using simulations of the Three Interaction Site (TIS) model for RNA. The heat…

Biomolecules · Quantitative Biology 2018-09-18 Naoto Hori , Natalia A. Denesyuk , D. Thirumalai

Two hypothesizes concerning interaction of neutrons with nanoparticles and having applications in the physics of ultracold neutron (UCN) were recently considered in ref. [Physics of Atomic Nuclei 65(3): 400 (2002)]; they were motivated by…

Nuclear Theory · Physics 2007-05-23 V. V. Nesvizhevsky

We report the observation of a distinct correlation between the kinetic fragility index $m$ and the reduced Arrhenius crossover temperature $\theta_A = T_A/T_g$ in various glass-forming liquids, identifying three distinguishable groups. In…

Soft Condensed Matter · Physics 2016-12-14 Abhishek Jaiswal , Takeshi Egami , K. F. Kelton , Kenneth S. Schweizer , Yang Zhang

Brittle failure is ubiquitous in amorphous materials that are sufficiently cooled below their glass transition temperature, $T_g$. This catastrophic failure mode is limiting for amorphous materials in many applications, and many fundamental…

Soft Condensed Matter · Physics 2019-04-02 Emily Y. Lin , Robert A. Riggleman

The thermodynamics of phase transitions between phases that are size-mismatched but coherent differs from conventional stress-free thermodynamics. Most notably, in open systems such phase transitions are always associated with hysteresis.…

Materials Science · Physics 2022-04-26 J. Magnus Rahm , Joakim Löfgren , Paul Erhart

Single-stranded RNA viruses co-assemble their capsid with the genome and variations in capsid structures can have significant functional relevance. In particular, viruses need to respond to a dehydrating environment to prevent genomic…

Heterogeneous nucleation of a new bulk phase on a flat substrate can be associated with the surface phase transition called wetting transition. When this bulk heterogeneous nucleation occurs on a completely-wettable flat substrate with a…

Soft Condensed Matter · Physics 2015-05-28 Masao Iwamatsu

Urea, a polar molecule with a large dipole moment, not only destabilizes the folded RNA structures, but can also enhance the folding rates of large ribozymes. Unlike the mechanism of urea-induced unfolding of proteins, which is well…

Biomolecules · Quantitative Biology 2017-08-23 Jeseong Yoon , D. Thirumalai , Changbong Hyeon

Using all atom molecular dynamics simulations, we report spontaneous unzipping and strong binding of small interfering RNA (siRNA) on graphene. Our dispersion corrected density functional theory based calculations suggest that nucleosides…

DNA and RNA are generally regarded as central molecules in molecular biology. Recent advancements in the field of DNA/RNA nanotechnology successfully used DNA/RNA as programmable molecules to construct molecular machines and nanostructures…

Biomolecules · Quantitative Biology 2019-04-01 Fan Hong , Petr Šulc

We give evidence of a clear structural signature of the glass transition, in terms of a static correlation length with the same dependence on the system size which is typical of critical phenomena. Our approach is to introduce an external,…

Statistical Mechanics · Physics 2010-06-25 Majid Mosayebi , Emanuela Del Gado , Patrick Ilg , Hans Christian Ottinger

We propose that glass-forming liquids are intrinsically under the influences of both fluctuating interactions and random fields well-known in the field of spin systems. This is due to the frustration between the isotropic and anisotropic…

Disordered Systems and Neural Networks · Physics 2009-10-30 Hajime Tanaka

Non-coding RNAs are ubiquitous, but the discovery of new RNA gene sequences far outpaces research on their structure and functional interactions. We mine the evolutionary sequence record to derive precise information about function and…

Biomolecules · Quantitative Biology 2016-04-22 Caleb Weinreb , Adam J. Riesselman , John B. Ingraham , Torsten Gross , Chris Sander , Debora S. Marks

We use Ising-like models to probe the thermal nature of Euclidean spacetime backgrounds. We determine which properties of the background -- curvature, the presence of a horizon, or temperature -- play a role in phase transitions. The…

General Relativity and Quantum Cosmology · Physics 2025-07-24 Mustafa Saeed , Diya Batool , Muhammad Muzammil , Nomaan X

The shapes of cooperatively rearranging regions in glassy liquids change from being compact at low temperatures to fractal or ``stringy'' as the dynamical crossover temperature from activated to collisional transport is approached from…

Soft Condensed Matter · Physics 2015-06-25 Jacob D. Stevenson , Joerg Schmalian , Peter G. Wolynes

In this paper we study the effect of energy parameters on minimum free energy (mfe) RNA secondary structures. Employing a simplified combinatorial energy model, that is only dependent on the diagram representation and that is not sequence…

Combinatorics · Mathematics 2012-05-17 Hillary S. W. Han , Christian M. Reidys

Graphynes and graphdiynes are carbon 2D allotrope structures presenting both sp2 and sp hybridized atoms. These materials have been theoretically predicted but due to intrinsic difficulties in their synthesis, only recently some of these…

Mesoscale and Nanoscale Physics · Physics 2017-02-21 Daniel Solis , Cristiano F. Woellner , Daiane D. Borges , Douglas S. Galvao

Random first order transition theory is used to determine the role of attractive and repulsive interactions in the dynamics of supercooled liquids. Self-consistent phonon theory, an approximate mean field treatment consistent with random…

Soft Condensed Matter · Physics 2007-09-13 Randall W. Hall , Peter G. Wolynes

We present a new type of phase-change behavior relevant for information storage applications, that can be observed in 2D systems with cluster-forming ability. The temperature-based control of the ordering in 2D particle systems depends on…

Statistical Mechanics · Physics 2019-04-30 Rogelio Díaz-Méndez , Guido Pupillo , Fabio Mezzacapo , Mats Wallin , Jack Lidmar , Egor Babaev

Considering marginally relevant and relevant deformations of the weakly coupled $(3+1)$-dimensional large $N$ conformal gauge theories introduced in arXiv:2011.13981, we study the patterns of phase transitions in these systems that lead to…

High Energy Physics - Theory · Physics 2021-09-15 Soumyadeep Chaudhuri , Eliezer Rabinovici
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