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In structure-based virtual screening, it is often necessary to evaluate the binding free energy of protein-ligand complexes by considering not only molecular conformations but also how these structures shift and rotate in space. The number…

Quantum Physics · Physics 2025-07-25 Pei-Kun Yang

Machine Learning has become very famous currently which assist in identifying the patterns from the raw data. Technological advancement has led to substantial improvement in Machine Learning which, thus helping to improve prediction.…

Machine Learning · Computer Science 2018-10-11 Prayag Tiwari , Massimo Melucci

We consider the problem of minimum-error quantum state discrimination for single-qubit mixed states. We present a method which uses the Helstrom conditions constructively and analytically; this algebraic approach is complementary to…

Quantum Physics · Physics 2017-09-25 Graeme Weir , Stephen M. Barnett , Sarah Croke

Quantum Machine Learning (QML) has emerged as a promising framework for exploring how quantum dynamics may enhance data processing tasks. Here we investigate Quantum Extreme Learning Machines (QELMs), a quantum analogue of classical Extreme…

Quantum Physics · Physics 2026-04-27 A. De Lorenzis , M. P. Casado , N. Lo Gullo , T. Lux , F. Plastina , A. Riera

Owing to their great expressivity and versatility, neural networks have gained attention for simulating large two-dimensional quantum many-body systems. However, their expressivity comes with the cost of a challenging optimization due to…

Disordered Systems and Neural Networks · Physics 2025-03-26 Hannah Lange , Guillaume Bornet , Gabriel Emperauger , Cheng Chen , Thierry Lahaye , Stefan Kienle , Antoine Browaeys , Annabelle Bohrdt

Quantum computation consists of a quantum state corresponding to a solution, and measurements with some observables. To obtain a solution with an accuracy $\epsilon$, measurements $O(n/\epsilon^2)$ are required, where $n$ is the size of a…

Quantum Physics · Physics 2023-04-13 Yoshiyuki Saito , Xinwei Lee , Dongsheng Cai , Nobuyoshi Asai

In machine learning, fewer features reduce model complexity. Carefully assessing the influence of each input feature on the model quality is therefore a crucial preprocessing step. We propose a novel feature selection algorithm based on a…

Quantum Physics · Physics 2023-02-22 Sascha Mücke , Raoul Heese , Sabine Müller , Moritz Wolter , Nico Piatkowski

We study the efficiency of algorithms simulating a system evolving with Hamiltonian $H=\sum_{j=1}^m H_j$. We consider high order splitting methods that play a key role in quantum Hamiltonian simulation. We obtain upper bounds on the number…

Quantum Physics · Physics 2010-10-12 Anargyros Papageorgiou , Chi Zhang

Hybrid quantum systems with different particle species are fundamental in quantum materials and quantum information science. In this work, we establish a rigorous theoretical framework proving that, given access to an unknown spin-boson…

Quantum Physics · Physics 2025-05-01 Lixing Zhang , Ze-Xun Lin , Prineha Narang , Di Luo

Quantum computing is a growing field where the information is processed by two-levels quantum states known as qubits. Current physical realizations of qubits require a careful calibration, composed by different experiments, due to noise and…

Quantum Physics · Physics 2023-09-15 Edoardo Pedicillo , Andrea Pasquale , Stefano Carrazza

Classification is a central task in deep learning algorithms. Usually, images are first captured and then processed by a sequence of operations, of which the artificial neuron represents one of the fundamental units. This paradigm requires…

Classification of medical images plays a vital role in medical image analysis; however, it remains challenging due to the limited availability of labeled data, class imbalances, and the complexity of medical patterns. To overcome these…

Accurate quantum state readout is crucial for error correction and algorithms, but measurement errors are detrimental. Readout fidelity is typically limited by a poor signal-to-noise ratio (SNR) and energy relaxation ($T_1$ decay), a…

Quantum Physics · Physics 2026-01-28 Samuel Jung , Neel Vora , Akel Hashim , Yilun Xu , Gang Huang

Quantum machine learning has emerged as a potential practical application of near-term quantum devices. In this work, we study a two-layer hybrid classical-quantum classifier in which a first layer of quantum stochastic neurons implementing…

Quantum Physics · Physics 2022-05-11 Ivana Nikoloska , Osvaldo Simeone

Variational hybrid quantum-classical optimization represents one of the most promising avenue to show the advantage of nowadays noisy intermediate-scale quantum computers in solving hard problems, such as finding the minimum-energy state of…

Quantum Physics · Physics 2020-11-18 Laura Gentini , Alessandro Cuccoli , Stefano Pirandola , Paola Verrucchi , Leonardo Banchi

Image classification is an important task in the field of machine learning and image processing. However, the usually used classification method --- the K Nearest-Neighbor algorithm has high complexity, because its two main processes:…

Computer Vision and Pattern Recognition · Computer Science 2018-05-17 Yijie Dang , Nan Jiang , Hao Hu , Zhuoxiao Ji , Wenyin Zhang

Quantum machine learning seeks a computational advantage in data processing by evaluating functions of quantum states, such as their similarity, that can be classically intractable to compute. For quantum advantage to be possible, however,…

We present a classical algorithm to find approximate solutions to instances of quadratic unconstrained binary optimisation. The algorithm can be seen as an analogue of quantum annealing under the restriction of a product state space, where…

Quantum Physics · Physics 2023-02-14 Joseph Bowles , Alexandre Dauphin , Patrick Huembeli , José Martinez , Antonio Acín

We present Quantum Cloning Machines (QCM) that transform N identical qubits into $M>N$ identical copies and we prove that the fidelity (quality) of these copies is optimal. The connection between cloning and measurement is discussed in…

Quantum Physics · Physics 2009-01-23 N. Gisin , S. Massar

We analyze the fundamental resolution of incoherent optical point sources from the perspective of a quantum detection problem: deciding whether the optical field on the image plane is generated by one source or two weaker sources with…

Quantum Physics · Physics 2019-11-07 Xiao-Ming Lu , Ranjith Nair , Mankei Tsang