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Multiple Sclerosis (MS) is a chronic autoimmune disease that can significantly reduce the quality of life of a patient. Existing treatment options can only help slow down the progression of the disease. Therefore, early detection and…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Abdul Basit , Ashir Rashid , Muhammad Abdullah Hanif , Muhammad Shafique

Schizophrenia is a debilitating, chronic mental disorder that significantly impacts an individual's cognitive abilities, behavior, and social interactions. It is characterized by subtle morphological changes in the brain, particularly in…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Nagur Shareef Shaik , Teja Krishna Cherukuri , Vince Calhoun , Dong Hye Ye

Schizophrenia is a chronic neuropsychiatric disorder that causes distinct structural alterations within the brain. We hypothesize that deep learning applied to a structural neuroimaging dataset could detect disease-related alteration and…

Image and Video Processing · Electrical Eng. & Systems 2022-07-08 Junhao Zhang , Vishwanatha M. Rao , Ye Tian , Yanting Yang , Nicolas Acosta , Zihan Wan , Pin-Yu Lee , Chloe Zhang , Lawrence S. Kegeles , Scott A. Small , Jia Guo

The heterogeneity of neurological conditions, ranging from structural anomalies to functional impairments, presents a significant challenge in medical imaging analysis tasks. Moreover, the limited availability of well-annotated datasets…

Image and Video Processing · Electrical Eng. & Systems 2024-07-15 Yang Ma , Dongang Wang , Peilin Liu , Lynette Masters , Michael Barnett , Weidong Cai , Chenyu Wang

Brain folding patterns have been reported to carry clinically relevant information. The brain folds mainly during the last trimester of pregnancy, and the process might be durably disturbed by preterm birth. Yet little is known about…

Neurons and Cognition · Quantitative Biology 2024-05-15 Julien Laval , Aymeric Gaudin , Vincent Frouin , Jessica Dubois , Andrea Gondova , Jean-François Mangin , Joël Chavas , Denis Rivière

Schizophrenia (SCZ) is a brain disorder where different people experience different symptoms, such as hallucination, delusion, flat-talk, disorganized thinking, etc. In the long term, this can cause severe effects and diminish life…

Machine Learning · Computer Science 2023-01-19 Shradha Verma , Tripti Goel , M Tanveer , Weiping Ding , Rahul Sharma , R Murugan

Schizophrenia (SCZ), as a chronic and persistent disorder, exhibits working memory deficits across various stages of the disorder, yet the neural mechanisms underlying these deficits remain elusive with inconsistent neuroimaging findings.…

Neurons and Cognition · Quantitative Biology 2023-10-16 Yuhao Yao , Shufang Zhang , Boyao Wang , Gaofeng Zhao , Hong Deng , Ying Chen

The timely identification of significant memory concern (SMC) is crucial for proactive cognitive health management, especially in an aging population. Detecting SMC early enables timely intervention and personalized care, potentially…

Machine Learning · Computer Science 2024-05-31 M. Sajid , Rahul Sharma , Iman Beheshti , M. Tanveer

Multiple sclerosis is a disease that affects the brain and spinal cord, it can lead to severe disability and has no known cure. The majority of prior work in machine learning for multiple sclerosis has been centered around using Magnetic…

Machine Learning · Computer Science 2023-09-12 Alexander Norcliffe , Lev Proleev , Diana Mincu , Fletcher Lee Hartsell , Katherine Heller , Subhrajit Roy

Several studies have shown that speech and language features, automatically extracted from clinical interviews or spontaneous discourse, have diagnostic value for mental disorders such as schizophrenia and bipolar disorder. They typically…

Computation and Language · Computer Science 2019-07-30 Rohit Voleti , Stephanie Woolridge , Julie M. Liss , Melissa Milanovic , Christopher R. Bowie , Visar Berisha

Introduction: Multiple Sclerosis (MS) is a chronic disease that affects millions of people across the globe. MS can critically affect different organs of the central nervous system such as the eyes, the spinal cord, and the brain.…

Image and Video Processing · Electrical Eng. & Systems 2023-02-21 Atif Shah , Maged S. Al-Shaibani , Moataz Ahmad , Reem Bunyan

Prevention of secondary brain injury is a core aim of neurocritical care, with Spreading Depolarizations (SDs) recognized as a significant independent cause. SDs are typically monitored through invasive, high-frequency electrocorticography…

Signal Processing · Electrical Eng. & Systems 2025-05-20 Jeanne Boyer-Chammard , Yinzhe Wu , Chenyu Zhang , Sharon Jewell , Anthony Strong , Guang Yang , Martyn Boutelle

Schizophrenia and bipolar disorder are debilitating psychiatric illnesses that can be challenging to diagnose accurately. The similarities between the diseases make it difficult to differentiate between them using traditional diagnostic…

Cortical lesions (CLs) have emerged as valuable biomarkers in multiple sclerosis (MS), offering high diagnostic specificity and prognostic relevance. However, their routine clinical integration remains limited due to subtle magnetic…

Accurate assessment of spheno-occipital synchondrosis (SOS) maturation is a key indicator of craniofacial growth and a critical determinant for orthodontic and surgical timing. However, SOS staging from cone-beam CT (CBCT) relies on subtle,…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Omid Halimi Milani , Amanda Nikho , Marouane Tliba , Lauren Mills , Emadeldeen Hamdan , Ahmet Enis Cetin , Mohammed H. Elnagar

Objective: Hydrocephalus is a medical condition in which there is an abnormal accumulation of cerebrospinal fluid (CSF) in the brain. Segmentation of brain imagery into brain tissue and CSF (before and after surgery, i.e. pre-op vs. postop)…

Image and Video Processing · Electrical Eng. & Systems 2018-09-11 Venkateswararao Cherukuri , Peter Ssenyonga , Benjamin C. Warf , Abhaya V. Kulkarni , Vishal Monga , Steven J. Schiff

Importance: The prevalence of severe mental illnesses (SMIs) in the United States is approximately 3% of the whole population. The ability to conduct risk screening of SMIs at large scale could inform early prevention and treatment.…

Artificial Intelligence · Computer Science 2023-01-13 Dianbo Liu , Karmel W. Choi , Paulo Lizano , William Yuan , Kun-Hsing Yu , Jordan W. Smoller , Isaac Kohane

We propose a weakly-supervised framework for the semantic segmentation of circular-scan synthetic-aperture-sonar (CSAS) imagery. The first part of our framework is trained in a supervised manner, on image-level labels, to uncover a set of…

The available evidence suggests that dynamic functional connectivity (dFC) can capture time-varying abnormalities in brain activity in resting-state cerebral functional magnetic resonance imaging (rs-fMRI) data and has a natural advantage…

Neurons and Cognition · Quantitative Biology 2023-09-13 Cheng Zhu , Ying Tan , Shuqi Yang , Jiaqing Miao , Jiayi Zhu , Huan Huang , Dezhong Yao , Cheng Luo

Multiple sclerosis (MS) affects the central nervous system with a wide range of symptoms. MS can, for example, cause pain, changes in mood and fatigue, and may impair a person's movement, speech and visual functions. Diagnosis of MS…

Computers and Society · Computer Science 2020-12-03 Patrick Schwab , Walter Karlen
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