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Complex interactions between genes or proteins contribute a substantial part to phenotypic evolution. Here we develop an evolutionarily grounded method for the cross-species analysis of interaction networks by {\em alignment}, which maps…

Molecular Networks · Quantitative Biology 2009-11-13 Johannes Berg , Michael Lässig

Many animals live in societies where individuals frequently interact socially with each other. The social structures of these systems can be studied in depth by means of network analysis. A large number of studies on animal social networks…

Populations and Evolution · Quantitative Biology 2021-02-22 Josefine Bohr Brask , Samuel Ellis , Darren P Croft

The ability to absorb mutations while retaining structure and function, or mutational robustness, is a remarkable property of natural proteins. In this Letter, we use a computational model of organismic evolution [Zeldovich et al, PLOS Comp…

Biomolecules · Quantitative Biology 2008-06-25 Konstantin B. Zeldovich , Eugene I. Shakhnovich

Taking inspiration from biological evolution, we explore the idea of "Can deep neural networks evolve naturally over successive generations into highly efficient deep neural networks?" by introducing the notion of synthesizing new highly…

Computer Vision and Pattern Recognition · Computer Science 2017-02-08 Mohammad Javad Shafiee , Akshaya Mishra , Alexander Wong

Sequence comparison and alignment has had an enormous impact on our understanding of evolution, biology, and disease. Comparison and alignment of biological networks will likely have a similar impact. Existing network alignments use…

Molecular Networks · Quantitative Biology 2009-10-08 Oleksii Kuchaiev , Tijana Milenkovic , Vesna Memisevic , Wayne Hayes , Natasa Przulj

It is a significant challenge to predict the network topology from a small amount of dynamical observations. Different from the usual framework of the node-based reconstruction, two optimization approaches (i.e., the global and partitioned…

Physics and Society · Physics 2016-03-03 Ming Xu , Chuan-Yun Xu , Huan Wang , Yong-Kui Li , Jing-Bo Hu , Ke-Fei Cao

Adaptive networks are a novel class of dynamical networks whose topologies and states coevolve. Many real-world complex systems can be modeled as adaptive networks, including social networks, transportation networks, neural networks and…

Social and Information Networks · Computer Science 2017-05-29 Hiroki Sayama , Irene Pestov , Jeffrey Schmidt , Benjamin James Bush , Chun Wong , Junichi Yamanoi , Thilo Gross

Distinct channels of interaction in a complex networked system define network layers, which co-exist and co-operate for the system's function. Towards realistic modeling and understanding such multiplex systems, we introduce and study a…

Physics and Society · Physics 2013-08-06 Jung Yeol Kim , K. -I. Goh

Gene and protein networks are very important to model complex large-scale systems in molecular biology. Inferring or reverseengineering such networks can be defined as the process of identifying gene/protein interactions from experimental…

Machine Learning · Computer Science 2017-03-10 Stefano Beretta , Mauro Castelli , Ivo Goncalves , Ivan Merelli , Daniele Ramazzotti

We propose new direction to understanding evolutionary dynamics of complex networks using two different types of collaboration networks: academic collaboration networks; and, disaster collaboration networks. The results show that academic…

Social and Information Networks · Computer Science 2015-03-29 Alireza Abbasi , Liaquat Hossain , Rolf T Wigand

The continuous interest in the social network area contributes to the fast development of this field. The new possibilities of obtaining and storing data facilitate deeper analysis of the entire social network, extracted social groups and…

Social and Information Networks · Computer Science 2017-01-18 Stanisław Saganowski , Piotr Bródka , Przemysław Kazienko

We show that the protein-protein interaction networks can be surprisingly well described by a very simple evolution model of duplication and divergence. The model exhibits a remarkably rich behavior depending on a single parameter, the…

Molecular Networks · Quantitative Biology 2009-11-10 I. Ispolatov , P. L. Krapivsky , A. Yuryev

Many social and biological networks consist of communities - groups of nodes within which connections are dense, but between which connections are sparser. Recently, there has been considerable interest in designing algorithms for detecting…

Physics and Society · Physics 2009-11-11 Chunguang Li , Philip K. Maini

Much of contemporary systems biology owes its success to the abstraction of a network, the idea that diverse kinds of molecular, cellular, and organismal species and interactions can be modeled as relational nodes and edges in a graph of…

Molecular Networks · Quantitative Biology 2017-05-26 Joseph L. Natale , David Hofmann , Damian G. Hernández , Ilya Nemenman

We present a general model for the growth of weighted networks in which the structural growth is coupled with the edges' weight dynamical evolution. The model is based on a simple weight-driven dynamics and a weights' reinforcement…

Statistical Mechanics · Physics 2009-11-10 Alain Barrat , Marc Barthelemy , Alessandro Vespignani

Protein complexes conserved across species indicate processes that are core to cellular machinery (e.g. cell-cycle or DNA damage-repair complexes conserved across human and yeast). While numerous computational methods have been devised to…

Molecular Networks · Quantitative Biology 2013-10-24 Phi Vu Nguyen , Sriganesh Srihari , Hon Wai Leong

Owing to the influence of real-world networks both in science and society, numerous mathematical models have been developed to understand the structure and evolution of these systems, particularly in a temporal context. Recent advancements…

Probability · Mathematics 2025-10-29 Sayan Banerjee , Shankar Bhamidi , Partha Dey , Akshay Sakanaveeti

Complex networks have non-trivial characteristics and appear in many real-world systems. Such networks are vitally important, but their full underlying dynamics are not completely understood. Utilizing new data sources, however, can unveil…

Social and Information Networks · Computer Science 2016-08-26 Michael Fire , Carlos Guestrin

We use a generalised version of the individual-based Tangled Nature model of evolutionary ecology to study the relationship between ecosystem structure and evolutionary history. Our evolved model ecosystems typically exhibit interaction…

Populations and Evolution · Quantitative Biology 2007-05-23 Simon Laird , Henrik Jeldtoft Jensen

We present a new model of the evolutionary dynamics and the growth of on-line social networks. The model emulates people's strategies for acquiring information in social networks, emphasising the local subjective view of an individual and…

Social and Information Networks · Computer Science 2013-10-01 Emanuele Massaro , Henrik Olsson , Andrea Guazzini , Franco Bagnoli
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