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The insulin sensitivity (IS) of the human body changes with a circadian rhythm. This adds to the time-varying feature of the glucose metabolism process and places challenges on the blood glucose (BG) control of patients with Type 1 Diabetes…
Accurately predicting blood glucose (BG) levels of ICU patients is critical, as both hypoglycemia (BG < 70 mg/dL) and hyperglycemia (BG > 180 mg/dL) are associated with increased morbidity and mortality. This study presents a…
Precise glucose level monitoring is critical for people with diabetes to avoid serious complications. While there are several methods for continuous glucose level monitoring, research on maintenance devices is limited. To mitigate the gap,…
In this paper, we build a new, simple, and interpretable mathematical model to estimate and forecast physiology related to the human glucose-insulin system, constrained by available data. By constructing a simple yet flexible model class…
This work presents a Model Predictive Control (MPC) for the artificial pancreas, which is able to autonomously manage basal insulin injections in type 1 diabetic patients. Specifically, the MPC goal is to maintain the patients' blood…
The human insulin-glucose metabolism is a time-varying process, which is partly caused by the changing insulin sensitivity of the body. This insulin sensitivity follows a circadian rhythm and its effects should be anticipated by any…
We present the design and \textit{in-silico} evaluation of a closed-loop insulin delivery algorithm to treat type 1 diabetes (T1D) consisting in a data-driven multi-step-ahead blood glucose (BG) predictor integrated into a Linear…
In this paper, we present a model free approach to calculate long-acting insulin doses for Type 2 Diabetic (T2D) subjects in order to bring their blood glucose (BG) concentration to be within a safe range. The proposed strategy tunes the…
The Glucose-Insulin-Glucagon nonlinear model [1-4] accurately describes how the body responds to exogenously supplied insulin and glucagon in patients affected by Type I diabetes. Based on this model, we design infusion rates of either…
A task of vital clinical importance, within Diabetes management, is the prevention of hypo/hyperglycemic events. Increasingly adopted Continuous Glucose Monitoring (CGM) devices offer detailed, non-intrusive and real time insights into a…
Continuous Blood Glucose (CGM) monitors have revolutionized the ability of diabetics to manage their blood glucose, and paved the way for artificial pancreas systems. In this paper we augment CGM data with sensor input collected by a smart…
The rising rates of diabetes necessitate innovative methods for its management. Continuous glucose monitors (CGM) are small medical devices that measure blood glucose levels at regular intervals providing insights into daily patterns of…
Effective management of Type 1 Diabetes requires continuous glucose monitoring and precise insulin adjustments to prevent hyperglycemia and hypoglycemia. With the growing adoption of wearable glucose monitors and mobile health applications,…
Continuous glucose monitoring (CGM) combined with AI offers new opportunities for proactive diabetes management through real-time glucose forecasting. However, most existing models are task-specific and lack generalization across patient…
Blood glucose (BG) management is crucial for type-1 diabetes patients resulting in the necessity of reliable artificial pancreas or insulin infusion systems. In recent years, deep learning techniques have been utilized for a more accurate…
To avoid serious diabetic complications, people with type 1 diabetes must keep their blood glucose levels (BGLs) as close to normal as possible. Insulin dosages and carbohydrate consumption are important considerations in managing BGLs.…
With continuous glucose monitoring (CGM), data-driven models on blood glucose prediction have been shown to be effective in related work. However, such (CGM) systems are not always available, e.g., for a patient at home. In this work, we…
This paper presents a novel approach to noninvasive hyperglycemia monitoring utilizing electrocardiograms (ECG) from an extensive database comprising 1119 subjects. Previous research on hyperglycemia or glucose detection using ECG has been…
Around a third of type 2 diabetes patients (T2D) are escalated to basal insulin injections. Basal insulin dose is titrated to achieve a tight glycemic target without undue hypoglycemic risk. In the standard of care (SoC), titration is based…
Diabetes encompasses a complex landscape of glycemic control that varies widely among individuals. However, current methods do not faithfully capture this variability at the meal level. On the one hand, expert-crafted features lack the…