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The human brain remains continuously active, whether an individual is working or at rest. Mental activity is a daily process, and if the brain becomes excessively active, known as overload, it can adversely affect human health. Recently,…

Signal Processing · Electrical Eng. & Systems 2024-03-13 Hong-Hai Nguyen , Ngumimi Karen Iyortsuun , Seungwon Kim , Hyung-Jeong Yang , Soo-Hyung Kim

Background: Dementia, particularly Alzheimer's Disease (AD), is a progressive neurodegenerative disorder marked by cognitive decline. Early detection, especially at the Mild Cognitive Impairment (MCI) stage, is essential for timely…

Signal Processing · Electrical Eng. & Systems 2025-10-16 Shivani Ranjan , Anant Jain , Robin Badal , Amit Kumar , Harshal Shende , Deepak Joshi , Pramod Yadav , Lalan Kumar

Large, open-source consortium datasets have spurred the development of new and increasingly powerful machine learning approaches in brain connectomics. However, one key question remains: are we capturing biologically relevant and…

Alzheimer's disease (AD) is one of the most common neurodegenerative diseases, with around 50 million patients worldwide. Accessible and non-invasive methods of diagnosing and characterising AD are therefore urgently required.…

Neurons and Cognition · Quantitative Biology 2021-07-14 Dominik Klepl , Fei He , Min Wu , Matteo De Marco , Daniel J. Blackburn , Ptolemaios Sarrigiannis

Objective: The Electroencephalogram (EEG) is gaining popularity as a physiological measure for neuroergonomics in human factor studies because it is objective, less prone to bias, and capable of assessing the dynamics of cognitive states.…

Human-Computer Interaction · Computer Science 2023-05-16 Kuan-Jung Chiang , Steven Dong , Chung-Kuan Cheng , Tzyy-Ping Jung

Resting-state fMRI is commonly used for diagnosing Autism Spectrum Disorder (ASD) by using network-based functional connectivity. It has been shown that ASD is associated with brain regions and their inter-connections. However,…

Neurons and Cognition · Quantitative Biology 2022-01-04 Ranjeet Ranjan Jha , Abhishek Bhardwaj , Devin Garg , Arnav Bhavsar , Aditya Nigam

Cybersickness poses a serious challenge for users of virtual reality (VR) technology. Consequently, there has been significant effort to track its occurrence during VR use with passive measures like brain activity recorded through…

Human-Computer Interaction · Computer Science 2026-03-30 Jacqueline Yau , Katherine J. Mimnaugh , Evan G. Center , Timo Ojala , Steven M. LaValle , Wenzhen Yuan , Nancy Amato , Minje Kim , Kara D. Federmeier

While differences in patterns of functional connectivity and neural synchronization have been reported between individuals on the autism spectrum and neurotypical peers at various age stages, these differences appear to be subtle and may…

Neurons and Cognition · Quantitative Biology 2025-07-15 Sungwoo Ahn , Leonid L Rubchinsky , Evie A Malaia

With the rising prevalence of cardiovascular diseases, electrocardiograms (ECG) remain essential for the non-invasive detection of cardiac abnormalities. This study presents a comprehensive evaluation of deep neural network architectures…

Signal Processing · Electrical Eng. & Systems 2026-02-23 Yun Song , Wenjia Zheng , Tiedan Chen , Ziyu Wang , Jiazhao Shi , Yisong Chen

This study investigates the potential of multimodal data integration, which combines electroencephalogram (EEG) data with sociodemographic characteristics like age, sex, education, and intelligence quotient (IQ), to diagnose mental diseases…

Machine Learning · Computer Science 2025-02-07 Himanshi Singh , Sadhana Tiwari , Sonali Agarwal , Ritesh Chandra , Sanjay Kumar Sonbhadra , Vrijendra Singh

Background: Electrocardiogram (ECG) analysis has emerged as a promising tool for detecting physiological changes linked to non-cardiac disorders. Given the close connection between cardiovascular and neurocognitive health, ECG abnormalities…

Signal Processing · Electrical Eng. & Systems 2025-11-20 Juan Miguel Lopez Alcaraz , Ebenezer Oloyede , David Taylor , Wilhelm Haverkamp , Nils Strodthoff

Identifying neural markers of stress and cognitive load is key to developing scalable tools for mental state assessment. This study evaluated whether a single-channel high-density EEG (hdrEEG) system could dissociate cognitive and…

Neurons and Cognition · Quantitative Biology 2025-07-15 Neta Batya Maimon , Lior Molcho , Talya Zaimer , Ofir Chibotero , Nathan Intrator , Eliezer Yahalom

Motor dysfunction is a common sign of neurodegenerative diseases (NDs) such as Parkinson's disease (PD) and Alzheimer's disease (AD), but may be difficult to detect, especially in the early stages. In this work, we examine the behavior of a…

Neurons and Cognition · Quantitative Biology 2025-10-23 Thomas Thebaud , Anna Favaro , Casey Chen , Gabrielle Chavez , Laureano Moro-Velazquez , Ankur Butala , Najim Dehak

Electroencephalography (EEG) signals reflect activities on certain brain areas. Effective classification of time-varying EEG signals is still challenging. First, EEG signal processing and feature engineering are time-consuming and highly…

Human-Computer Interaction · Computer Science 2019-08-27 Xiang Zhang , Lina Yao , Xianzhi Wang , Wenjie Zhang , Shuai Zhang , Yunhao Liu

We propose a new representation learning solution for the classification of cognitive load based on Electroencephalogram (EEG). Our method integrates both time and frequency domains by first passing the raw EEG signals through the…

Human-Computer Interaction · Computer Science 2025-11-18 Prithila Angkan , Amin Jalali , Paul Hungler , Ali Etemad

Autism spectrum disorder (ASD) has been associated with structural alterations across cortical and subcortical regions. Quantitative neuroimaging enables large-scale analysis of these neuroanatomical patterns. This project used structural…

Neurons and Cognition · Quantitative Biology 2025-12-30 Ashley Chen

In this paper, we analyze electroencephalograms (EEG) which are recordings of brain electrical activity. We develop new clustering methods for identifying synchronized brain regions, where the EEGs show similar oscillations or waveforms…

Methodology · Statistics 2020-07-29 Tianbo Chen , Ying Sun , Carolina Euan , Hernando Ombao

Electroencephalography (EEG) is a widely used tool for diagnosing brain disorders due to its high temporal resolution, non-invasive nature, and affordability. Manual analysis of EEG is labor-intensive and requires expertise, making…

Signal Processing · Electrical Eng. & Systems 2024-11-19 Salim Rukhsar , Anil Kumar Tiwari

For many years now, understanding the brain mechanism has been a great research subject in many different fields. Brain signal processing and especially electroencephalogram (EEG) has recently known a growing interest both in academia and…

Neurons and Cognition · Quantitative Biology 2022-04-18 Victor Delvigne , Hazem Wannous , Jean-Philippe Vandeborre , Laurence Ris , Thierry Dutoit

Autism Spectrum Disorder (ASD) is a neurodevelopmental condition characterized by atypical brain connectivity. One of the crucial steps in addressing ASD is its early detection. This study introduces a novel computational framework that…

Applications · Statistics 2026-03-31 Abigail Kelly , Ramchandra Rimal , Arpan Sainju
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