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The Gleason grading system using histological images is the most powerful diagnostic and prognostic predictor of prostate cancer. The current standard inspection is evaluating Gleason H&E-stained histopathology images by pathologists.…

Image and Video Processing · Electrical Eng. & Systems 2020-12-10 Haotian Xie , Yong Zhang , Jun Wang , Jingjing Zhang , Yifan Ma , Zhaogang Yang

Whole Slide Images (WSIs) play a crucial role in accurate cancer diagnosis and prognosis, as they provide tissue details at the cellular level. However, the rapid growth of computational tasks involving WSIs poses significant challenges.…

Computer Vision and Pattern Recognition · Computer Science 2025-10-30 Doanh C. Bui , Hoai Luan Pham , Vu Trung Duong Le , Tuan Hai Vu , Van Duy Tran , Khang Nguyen , Yasuhiko Nakashima

Oncologists often rely on a multitude of data, including whole-slide images (WSIs), to guide therapeutic decisions, aiming for the best patient outcome. However, predicting the prognosis of cancer patients can be a challenging task due to…

Image and Video Processing · Electrical Eng. & Systems 2025-04-01 M Rita Verdelho , Alexandre Bernardino , Catarina Barata

Whole slide images (WSI) are microscopy images of stained tissue slides routinely prepared for diagnosis and treatment selection in medical practice. WSI are very large (gigapixel size) and complex (made of up to millions of cells). The…

Computer Vision and Pattern Recognition · Computer Science 2022-12-08 Tristan Lazard , Marvin Lerousseau , Etienne Decencière , Thomas Walter

Medical hyperspectral imaging (MHSI) has shown strong potential for disease diagnosis by capturing spectral-spatial information of tissues. While deep learning has substantially improved MHSI classification accuracy, its robustness remains…

Computer Vision and Pattern Recognition · Computer Science 2026-04-22 Yunrui Gu , Zhenzhe Gao , Cong Kong , Jiawei Du , Zhaoxia Yin

Supervised deep learning methods have achieved considerable success in medical image analysis, owing to the availability of large-scale and well-annotated datasets. However, creating such datasets for whole slide images (WSIs) in…

Computer Vision and Pattern Recognition · Computer Science 2024-06-10 Hao Wang , Euijoon Ahn , Jinman Kim

We propose a new method for cancer subtype classification from histopathological images, which can automatically detect tumor-specific features in a given whole slide image (WSI). The cancer subtype should be classified by referring to a…

Computer Vision and Pattern Recognition · Computer Science 2020-04-03 Noriaki Hashimoto , Daisuke Fukushima , Ryoichi Koga , Yusuke Takagi , Kaho Ko , Kei Kohno , Masato Nakaguro , Shigeo Nakamura , Hidekata Hontani , Ichiro Takeuchi

Histopathology whole slide images (WSIs) play a very important role in clinical studies and serve as the gold standard for many cancer diagnoses. However, generating automatic tools for processing WSIs is challenging due to their enormous…

Computer Vision and Pattern Recognition · Computer Science 2022-09-28 Jingwei Zhang , Xin Zhang , Ke Ma , Rajarsi Gupta , Joel Saltz , Maria Vakalopoulou , Dimitris Samaras

Objective: We develop a computer-aided diagnosis (CAD) system using deep learning approaches for lesion detection and classification on whole-slide images (WSIs) with breast cancer. The deep features being distinguishing in classification…

Image and Video Processing · Electrical Eng. & Systems 2021-08-29 Wei-Wen Hsu , Yongfang Wu , Chang Hao , Yu-Ling Hou , Xiang Gao , Yun Shao , Xueli Zhang , Tao He , Yanhong Tai

Classification of gigapixel Whole Slide Images (WSIs) is an important prediction task in the emerging area of computational pathology. There has been a surge of research in deep learning models for WSI classification with clinical…

Computer Vision and Pattern Recognition · Computer Science 2023-05-04 Sajid Javed , Arif Mahmood , Talha Qaiser , Naoufel Werghi , Nasir Rajpoot

Graph neural network (GNN), as a powerful representation learning model on graph data, attracts much attention across various disciplines. However, recent studies show that GNN is vulnerable to adversarial attacks. How to make GNN more…

Machine Learning · Computer Science 2019-05-14 Shen Wang , Zhengzhang Chen , Jingchao Ni , Xiao Yu , Zhichun Li , Haifeng Chen , Philip S. Yu

The idea of robustness is central and critical to modern statistical analysis. However, despite the recent advances of deep neural networks (DNNs), many studies have shown that DNNs are vulnerable to adversarial attacks. Making…

Cryptography and Security · Computer Science 2023-06-02 Jungeum Kim , Xiao Wang

Graph Neural Networks (GNNs) have emerged as a dominant paradigm for learning on graph-structured data, thanks to their ability to jointly exploit node features and relational information encoded in the graph topology. This joint modeling,…

Machine Learning · Computer Science 2025-12-30 Yongyu Wang

The notion of adversarial attacks on image classification models based on convolutional neural networks (CNN) is introduced in this work. To classify images, deep learning models called CNNs are frequently used. However, when the networks…

Computer Vision and Pattern Recognition · Computer Science 2023-12-29 Jaydip Sen , Abhiraj Sen , Ananda Chatterjee

Adversarial attacks have been fairly explored for computer vision and vision-language models. However, the avenue of adversarial attack for the vision language segmentation models (VLSMs) is still under-explored, especially for medical…

Computer Vision and Pattern Recognition · Computer Science 2025-05-07 Anjila Budathoki , Manish Dhakal

Graph deep learning models, such as graph convolutional networks (GCN) achieve remarkable performance for tasks on graph data. Similar to other types of deep models, graph deep learning models often suffer from adversarial attacks. However,…

Machine Learning · Computer Science 2019-05-23 Huijun Wu , Chen Wang , Yuriy Tyshetskiy , Andrew Docherty , Kai Lu , Liming Zhu

Computational methods on analyzing Whole Slide Images (WSIs) enable early diagnosis and treatments by supporting pathologists in detection and classification of tumors. However, the extremely high resolution of WSIs makes end-to-end…

Computer Vision and Pattern Recognition · Computer Science 2026-03-18 Umar Marikkar , Muhammad Awais , Sara Atito

Prostate cancer grading from whole-slide images (WSIs) remains a challenging task due to the large-scale nature of WSIs, the presence of heterogeneous tissue structures, and difficulty of selecting diagnostically relevant regions. Existing…

Computer Vision and Pattern Recognition · Computer Science 2025-12-12 Masum Shah Junayed , John Derek Van Vessem , Qian Wan , Gahie Nam , Sheida Nabavi

The reliance on deep learning algorithms has grown significantly in recent years. Yet, these models are highly vulnerable to adversarial attacks, which introduce visually imperceptible perturbations into testing data to induce…

Machine Learning · Computer Science 2019-06-14 Rajeev Sahay , Rehana Mahfuz , Aly El Gamal

Machine learning techniques are immensely deployed in both industry and academy. Recent studies indicate that machine learning models used for classification tasks are vulnerable to adversarial examples, which limits the usage of…

Computer Vision and Pattern Recognition · Computer Science 2020-07-14 Yutong Gao , Yi Pan