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Motivation: Flux balance analysis, and its variants, are widely used methods for predicting steady-state reaction rates in biochemical reaction networks. The exploration of high dimensional networks with such methods is currently hampered…

Quantitative Methods · Quantitative Biology 2016-11-17 Laurent Heirendt , Ronan M. T. Fleming , Ines Thiele

QC Lab is an open-source Python package for QC dynamics simulations aimed to promote the development of QC algorithms, and their application to a wide variety of relevant model problems. It follows a modular design that facilitates…

Chemical Physics · Physics 2025-10-28 Alex Krotz , Ethan Byrd , Ken Miyazaki , Roel Tempelaar

Computational chemistry is the leading application to demonstrate the advantage of quantum computing in the near term. However, large-scale simulation of chemical systems on quantum computers is currently hindered due to a mismatch between…

Quantum Physics · Physics 2021-05-18 Gushu Li , Yunong Shi , Ali Javadi-Abhari

Optimization for different tasks like material characterization, synthesis, and functional properties for desired applications over multi-dimensional control parameters need a rapid strategic search through active learning such as Bayesian…

Machine Learning · Computer Science 2026-03-16 Arpan Biswas , Hiroshi Funakubo , Yongtao Liu

The importance of computers is continually increasing in radiotherapy. Efficient algorithms, implementations and the ability to leverage advancements in computer science are crucial to improve cancer care even further and deliver the best…

Medical Physics · Physics 2024-07-08 Renato Bellotti , Antony J. Lomax , Andreas Adelmann , Jan Hrbacek

Consensus-based optimization (CBO) is a versatile multi-particle optimization method for performing nonconvex and nonsmooth global optimizations in high dimensions. Proofs of global convergence in probability have been achieved for a broad…

Optimization and Control · Mathematics 2026-01-13 Jonas Beddrich , Enis Chenchene , Massimo Fornasier , Hui Huang , Barbara Wohlmuth

TensorX is a Python library for prototyping, design, and deployment of complex neural network models in TensorFlow. A special emphasis is put on ease of use, performance, and API consistency. It aims to make available high-level components…

Machine Learning · Computer Science 2021-01-05 Davide Nunes , Luis Antunes

In this article, we propose an interval constraint programming method for globally solving catalog-based categorical optimization problems. It supports catalogs of arbitrary size and properties of arbitrary dimension, and does not require…

Optimization and Control · Mathematics 2024-01-23 Charlie Vanaret

The Python programming language is best known for its syntax and scientific libraries, but it is also notorious for its slow interpreter. Optimizing critical sections in Python entails special knowledge of the binary interactions between…

Programming Languages · Computer Science 2025-07-02 Isabella Basso do Amaral , Renato Cordeiro Ferreira , Alfredo Goldman

This paper studies the problem of globally optimizing a variable of interest that is part of a causal model in which a sequence of interventions can be performed. This problem arises in biology, operational research, communications and,…

Machine Learning · Statistics 2020-05-27 Virginia Aglietti , Xiaoyu Lu , Andrei Paleyes , Javier González

In this paper, we propose a predictor-corrector type Consensus Based Optimization (CBO) algorithm on a convex feasible set. Our proposed algorithm generalizes the CBO algorithm in [11] to tackle a constrained optimization problem for the…

Optimization and Control · Mathematics 2021-10-14 Hyeong-Ohk Bae , Seung-Yeal Ha , Myeongju Kang , Hyuncheul Lim , Chanho Min , Jane Yoo

Computational reproducibility of scientific results, that is, the execution of a computational experiment (e.g., a script) using its original settings (data, code, etc.), should always be possible. However, reproducibility has become a…

Human-Computer Interaction · Computer Science 2025-04-15 Lázaro Costa , Susana Barbosa , Jácome Cunha

The Fujitsu A64FX ARM-based processor is used in supercomputers such as Fugaku in Japan and Isambard 2 in the UK and provides an interesting combination of hardware features such as Scalable Vector Extension (SVE), and native support for…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-10-20 Mosè Giordano , Milan Klöwer , Valentin Churavy

Despite a surge collection of XAI methods, users still struggle to obtain required AI explanations. Previous research suggests chatbots as dynamic solutions, but the effective design of conversational XAI agents for practical human needs…

Human-Computer Interaction · Computer Science 2023-10-30 Hua Shen , Chieh-Yang Huang , Tongshuang Wu , Ting-Hao 'Kenneth' Huang

Biips is a software platform for automatic Bayesian inference with interacting particle systems. Biips allows users to define their statistical model in the probabilistic programming BUGS language, as well as to add custom functions or…

Computation · Statistics 2014-12-12 Adrien Todeschini , François Caron , Marc Fuentes , Pierrick Legrand , Pierre Del Moral

BayesOpt is a library with state-of-the-art Bayesian optimization methods to solve nonlinear optimization, stochastic bandits or sequential experimental design problems. Bayesian optimization is sample efficient by building a posterior…

Machine Learning · Computer Science 2014-05-30 Ruben Martinez-Cantin

We introduce ACEpotentials.jl, a Julia-language software package that constructs interatomic potentials from quantum mechanical reference data using the Atomic Cluster Expansion (Drautz, 2019). As the latter provides a complete description…

Computational Workflows are widely used in data analysis, enabling innovation and decision-making. In many domains (bioinformatics, image analysis, & radio astronomy) the analysis components are numerous and written in multiple different…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-05-24 Michael R. Crusoe , Sanne Abeln , Alexandru Iosup , Peter Amstutz , John Chilton , Nebojša Tijanić , Hervé Ménager , Stian Soiland-Reyes , Bogdan Gavrilovic , Carole Goble

The Julia programming language has gained acceptance within the High-Performance Computing (HPC) community due to its ability to tackle two-language problem: Julia code feels as high-level as Python but allows developers to tune it to…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-04-17 Sergio Sanchez-Ramirez , Mosè Giordano