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Unsupervised Anomaly Detection (UAD) plays a crucial role in identifying abnormal patterns within data without labeled examples, holding significant practical implications across various domains. Although the individual contributions of…

Machine Learning · Computer Science 2024-06-04 Zeyu Fang , Ming Gu , Sheng Zhou , Jiawei Chen , Qiaoyu Tan , Haishuai Wang , Jiajun Bu

Objective: The study aims to address the challenge of aligning Standard Fundus Images (SFIs) and Ultra-Widefield Fundus Images (UWFIs), which is difficult due to their substantial differences in viewing range and the amorphous appearance of…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Kanggeon Lee , Su Jeong Song , Soochahn Lee , Kyoung Mu Lee

Machine learning (ML) algorithms are optimized for the distribution represented by the training data. For outlier data, they often deliver predictions with equal confidence, even though these should not be trusted. In order to deploy…

Image and Video Processing · Electrical Eng. & Systems 2021-03-17 Milda Pocevičiūtė , Gabriel Eilertsen , Claes Lundström

In this paper we consider the problem of unsupervised anomaly segmentation in medical images, which has attracted increasing attention in recent years due to the expensive pixel-level annotations from experts and the existence of a large…

Image and Video Processing · Electrical Eng. & Systems 2021-12-20 Raunak Dey , Wenbo Sun , Haibo Xu , Yi Hong

Automated nodule segmentation is essential for computer-assisted diagnosis in ultrasound images. Nevertheless, most existing methods depend on precise pixel-level annotations by medical professionals, a process that is both costly and…

Computer Vision and Pattern Recognition · Computer Science 2024-07-19 Xingyue Zhao , Peiqi Li , Xiangde Luo , Meng Yang , Shi Chang , Zhongyu Li

Noise-inclusive fully unsupervised anomaly detection (FUAD) holds significant practical relevance. Although various methods exist to address this problem, they are limited in both performance and scalability. Our work seeks to overcome…

Image and Video Processing · Electrical Eng. & Systems 2025-06-19 Chengming Liu , Fengjie Wang , Lei Shi , Zhe Zhao

Automated visual inspection in medical-device manufacturing faces unique challenges, including extremely low defect rates, limited annotated data, hardware restrictions on production lines, and the need for validated, explainable…

Computer Vision and Pattern Recognition · Computer Science 2025-11-14 Julio Zanon Diaz , Georgios Siogkas , Peter Corcoran

Unsupervised image anomaly detection (UAD) has become a critical process in industrial and medical applications, but it faces growing challenges due to increasing concerns over data privacy. The limited class diversity inherent to one-class…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-12-30 Silin Chen , Andy Liu , Kangjian Di , Yichu Xu , Han-Jia Ye , Wenhan Luo , Ningmu Zou

Reliable automated analysis of Optical Coherence Tomography (OCT) imaging is crucial for diagnosing retinal disorders but faces a critical barrier: the need for expensive, labor-intensive expert annotations. Supervised deep learning models…

Computer Vision and Pattern Recognition · Computer Science 2026-04-27 Tania Haghighi , Sina Gholami , Hamed Tabkhi , Minhaj Nur Alam

Traditional supervised medical image segmentation models require large amounts of labeled data for training; however, obtaining such large-scale labeled datasets in the real world is extremely challenging. Recent semi-supervised…

Computer Vision and Pattern Recognition · Computer Science 2025-05-26 Yunyao Lu , Yihang Wu , Reem Kateb , Ahmad Chaddad

In the literature, coarse-to-fine or scale-recurrent approach i.e. progressively restoring a clean image from its low-resolution versions has been successfully employed for single image deblurring. However, a major disadvantage of existing…

Computer Vision and Pattern Recognition · Computer Science 2021-12-14 Praveen Kandula , Rajagopalan. A. N

The Segment Anything Model (SAM) exhibits a capability to segment a wide array of objects in natural images, serving as a versatile perceptual tool for various downstream image segmentation tasks. In contrast, medical image segmentation…

Computer Vision and Pattern Recognition · Computer Science 2023-08-29 Yizhe Zhang , Tao Zhou , Shuo Wang , Ye Wu , Pengfei Gu , Danny Z. Chen

T2 hyperintensities in spinal cord MR images are crucial biomarkers for conditions such as degenerative cervical myelopathy. However, current clinical diagnoses primarily rely on manual evaluation. Deep learning methods have shown promise…

Image and Video Processing · Electrical Eng. & Systems 2025-03-18 Qi Zhang , Xiuyuan Chen , Ziyi He , Kun Wang , Lianming Wu , Hongxing Shen , Jianqi Sun

Anomaly detection is an emerging approach in digital pathology for its ability to efficiently and effectively utilize data for disease diagnosis. While supervised learning approaches deliver high accuracy, they rely on extensively annotated…

Image and Video Processing · Electrical Eng. & Systems 2025-08-22 Jiamu Wang , Keunho Byeon , Jinsol Song , Anh Nguyen , Sangjeong Ahn , Sung Hak Lee , Jin Tae Kwak

Unsupervised anomaly detection (UAD) alleviates large labeling efforts by training exclusively on unlabeled in-distribution data and detecting outliers as anomalies. Generally, the assumption prevails that large training datasets allow the…

Computer Vision and Pattern Recognition · Computer Science 2024-10-29 Felix Meissen , Johannes Getzner , Alexander Ziller , Özgün Turgut , Georgios Kaissis , Martin J. Menten , Daniel Rueckert

Reliable anomaly detection in brain MRI remains challenging due to the scarcity of annotated abnormal cases and the frequent absence of key imaging modalities in real clinical workflows. Existing single-class or multi-class anomaly…

Computer Vision and Pattern Recognition · Computer Science 2025-12-25 Changwei Wu , Yifei Chen , Yuxin Du , Mingxuan Liu , Jinying Zong , Beining Wu , Jie Dong , Feiwei Qin , Yunkang Cao , Qiyuan Tian

Pathological anomalies exhibit diverse appearances in medical imaging, making it difficult to collect and annotate a representative amount of data required to train deep learning models in a supervised setting. Therefore, in this work, we…

Image and Video Processing · Electrical Eng. & Systems 2023-07-18 Mariana-Iuliana Georgescu

Semi-supervised learning (SSL) for medical image segmentation is a challenging yet highly practical task, which reduces reliance on large-scale labeled dataset by leveraging unlabeled samples. Among SSL techniques, the weak-to-strong…

Computer Vision and Pattern Recognition · Computer Science 2024-10-18 Shiao Xie , Hongyi Wang , Ziwei Niu , Hao Sun , Shuyi Ouyang , Yen-Wei Chen , Lanfen Lin

Structural health monitoring (SHM) has experienced significant advancements in recent decades, accumulating massive monitoring data. Data anomalies inevitably exist in monitoring data, posing significant challenges to their effective…

Machine Learning · Computer Science 2024-12-06 Mingyuan Zhou , Xudong Jian , Ye Xia , Zhilu Lai

The variability introduced by differences in MRI scanner models, acquisition protocols, and imaging sites hinders consistent analysis and generalizability across multicenter studies. We present a novel image-based harmonization framework…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Luca Caldera , Lara Cavinato , Francesca Ieva