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Graphical models are commonly used to discover associations within gene or protein networks for complex diseases such as cancer. Most existing methods estimate a single graph for a population, while in many cases, researchers are interested…

Cancer survival prediction requires integrating pathological Whole Slide Images (WSIs) and genomic profiles, a challenging task due to the inherent heterogeneity and the complexity of modeling both inter- and intra-modality interactions.…

Image and Video Processing · Electrical Eng. & Systems 2025-07-08 Mingxin Liu , Chengfei Cai , Jun Li , Pengbo Xu , Jinze Li , Jiquan Ma , Jun Xu

Learning-to-Rank (LTR) models trained from implicit feedback (e.g. clicks) suffer from inherent biases. A well-known one is the position bias -- documents in top positions are more likely to receive clicks due in part to their position…

Information Retrieval · Computer Science 2020-07-21 Mucun Tian , Chun Guo , Vito Ostuni , Zhen Zhu

Causal representation learning (CRL) models aim to transform high-dimensional data into a latent space, enabling interventions to generate counterfactual samples or modify existing data based on the causal relationships among latent…

Machine Learning · Computer Science 2026-03-19 Alireza Sadeghi , Wael AbdAlmageed

Heterogeneous graphs can well describe the complex entity relationships in the real world. For example, online shopping networks contain multiple physical types of consumers and products, as well as multiple relationship types such as…

Machine Learning · Computer Science 2024-07-02 Jing Zhang , Xiaoqian Jiang , Yingjie Xie , Cangqi Zhou

Counterfactual prediction is a fundamental task in decision-making. G-computation is a method for estimating expected counterfactual outcomes under dynamic time-varying treatment strategies. Existing G-computation implementations have…

Machine Learning · Computer Science 2020-03-25 Rui Li , Zach Shahn , Jun Li , Mingyu Lu , Prithwish Chakraborty , Daby Sow , Mohamed Ghalwash , Li-wei H. Lehman

No unmeasured confounding is a common assumption when reasoning about counterfactual outcomes, but such an assumption may not be plausible in observational studies. Sensitivity analysis is often employed to assess the robustness of causal…

Methodology · Statistics 2025-08-20 Abhinandan Dalal , Eric J. Tchetgen Tchetgen

Predicting the impact of treatments from observational data only still represents a majorchallenge despite recent significant advances in time series modeling. Treatment assignments are usually correlated with the predictors of the…

Machine Learning · Computer Science 2022-02-25 Edward De Brouwer , Javier González Hernández , Stephanie Hyland

Estimation of conditional average treatment effects (CATEs) plays an essential role in modern medicine by informing treatment decision-making at a patient level. Several metalearners have been proposed recently to estimate CATEs in an…

Applications · Statistics 2022-09-07 Yizhe Xu , Nikolaos Ignatiadis , Erik Sverdrup , Scott Fleming , Stefan Wager , Nigam Shah

The success of Transformer-based models has encouraged many researchers to learn CAD models using sequence-based approaches. However, learning CAD models is still a challenge, because they can be represented as complex shapes with long…

Computer Vision and Pattern Recognition · Computer Science 2024-04-03 Minseop Jung , Minseong Kim , Jibum Kim

The lack of labeled data is a key challenge for learning useful representation from time series data. However, an unsupervised representation framework that is capable of producing high quality representations could be of great value. It is…

Machine Learning · Statistics 2022-03-18 Kristoffer Wickstrøm , Michael Kampffmeyer , Karl Øyvind Mikalsen , Robert Jenssen

Identifying unique characteristics in a network through comparison with another network is an essential network analysis task. For example, with networks of protein interactions obtained from normal and cancer tissues, we can discover…

Machine Learning · Computer Science 2022-02-16 Takanori Fujiwara , Jian Zhao , Francine Chen , Yaoliang Yu , Kwan-Liu Ma

Contrastive learning has been used to learn a high-quality representation of the image in computer vision. However, contrastive learning is not widely utilized in natural language processing due to the lack of a general method of data…

Computation and Language · Computer Science 2021-04-29 Peng Su , Yifan Peng , K. Vijay-Shanker

Contrastive representation learning (CRL) underpins many modern foundation models. Despite recent theoretical progress, existing analyses suffer from several key limitations: (i) the statistical consistency of CRL remains poorly understood;…

Machine Learning · Computer Science 2026-05-29 Yuanfan Li , Xiyuan Wei , Tianbao Yang , Yiming Ying

Inferring the heterogeneous treatment effect is a fundamental problem in the sciences and commercial applications. In this paper, we focus on estimating Conditional Average Treatment Effect (CATE), that is, the difference in the conditional…

Methodology · Statistics 2021-03-23 Haomiao Meng , Xingye Qiao

In causal inference, estimating heterogeneous treatment effects (HTE) is critical for identifying how different subgroups respond to interventions, with broad applications in fields such as precision medicine and personalized advertising.…

Machine Learning · Computer Science 2024-07-02 Jiehui Zhou , Linxiao Yang , Xingyu Liu , Xinyue Gu , Liang Sun , Wei Chen

Multi-view learning has progressed rapidly in recent years. Although many previous studies assume that each instance appears in all views, it is common in real-world applications for instances to be missing from some views, resulting in…

Machine Learning · Computer Science 2022-08-30 Pengfei Zhu , Xinjie Yao , Yu Wang , Meng Cao , Binyuan Hui , Shuai Zhao , Qinghua Hu

Deep Bregman divergence measures divergence of data points using neural networks which is beyond Euclidean distance and capable of capturing divergence over distributions. In this paper, we propose deep Bregman divergences for contrastive…

Computer Vision and Pattern Recognition · Computer Science 2021-11-24 Mina Rezaei , Farzin Soleymani , Bernd Bischl , Shekoofeh Azizi

Conditional average treatment effects (CATEs) allow us to understand the effect heterogeneity across a large population of individuals. However, typical CATE learners assume all confounding variables are measured in order for the CATE to be…

Machine Learning · Computer Science 2022-02-01 Yao Zhang , Jeroen Berrevoets , Mihaela van der Schaar

The simultaneous application of multiple treatments is increasingly common in many fields, such as healthcare and marketing. In such scenarios, it is important to estimate the single treatment effects and the interaction treatment effects…

Methodology · Statistics 2025-11-14 Yuki Murakami , Takumi Hattori , Kohsuke Kubota