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Circadian rhythmicity lies at the center of various important physiological and behavioral processes in mammals, such as sleep, metabolism, homeostasis, mood changes and more. It has been shown that this rhythm arises from self-sustained…

Neurons and Cognition · Quantitative Biology 2023-02-08 Yorgos M. Psarellis , Michail Kavousanakis , Michael A. Henson , Ioannis G. Kevrekidis

An increasing body of evidence suggests that the trial-to-trial variability of spiking activity in the brain is not mere noise, but rather the reflection of a sampling-based encoding scheme for probabilistic computing. Since the precise…

Low-rank pseudoinverses are widely used to approximate matrix inverses in scalable machine learning, optimization, and scientific computing. However, real-world matrices are often observed with noise, arising from sampling, sketching, and…

Machine Learning · Computer Science 2025-10-30 Phuc Tran , Nisheeth K. Vishnoi

Simultaneously measuring the activities of all neurons in a mammalian brain at millisecond resolution is a challenge beyond the limits of existing techniques in neuroscience. Entirely new approaches may be required, motivating an analysis…

Neuronal ensemble activity, including coordinated and oscillatory patterns, exhibits hallmarks of nonequilibrium systems with time-asymmetric trajectories to maintain their organization. However, assessing time asymmetry from neuronal…

Neurons and Cognition · Quantitative Biology 2025-12-12 Ken Ishihara , Hideaki Shimazaki

Peripheral Nerve Stimulation (PNS) constrains the clinical performance of Magnetic Resonance and Particle Imaging (MRI and MPI) systems. Extensive magneto-stimulation studies have been carried out recently in the field of MPI, where typical…

It is currently accepted that cortical maps are dynamic constructions that are altered in response to external input. Experience-dependent structural changes in cortical microcurcuts lead to changes of activity, i.e. to changes in…

Neurons and Cognition · Quantitative Biology 2013-02-26 F. Gafarov , N. Khusnutdinov , F. Galimyanov

In this paper, we investigate the fundamental limits on how the inter- spike time of a neuron oscillator can be perturbed by the application of a bounded external control input (a current stimulus) with zero net electric charge…

Optimization and Control · Mathematics 2012-11-20 Isuru S. Dasanayake , Jr-Shin Li

We study the vibrational motion of membrane resonators upon strong drive in the strongly nonlinear regime. By imaging the vibrational state of rectangular siliconnitride membrane resonators and by analyzing the frequency response using…

Mesoscale and Nanoscale Physics · Physics 2019-04-24 Fan Yang , Felix Rochau , Jana Huber , Alexandre Brieussel , Gianluca Rastelli , Eva M. Weig , Elke Scheer

Model-based studies of auditory nerve responses to electrical stimulation can provide insight into the functioning of cochlear implants. Ideally, these studies can identify limitations in sound processing strategies and lead to improved…

Neurons and Cognition · Quantitative Biology 2015-08-07 Joshua H. Goldwyn , Jay T. Rubinstein , Eric Shea-Brown

An asymptotic model based on a reductive perturbative expansion of the drift kinetic and the Maxwell equations is used to demonstrate that, near the instability threshold, the nonlinear dynamics of mirror modes in a magnetized plasma with…

Plasma Physics · Physics 2015-05-13 E. A. Kuznetsov , T. Passot , P. L. Sulem

We use mean field theory to study the response properties of a simple randomly-connected model cortical network of leaky integrate-and-fire neurons with balanced excitation and inhibition. The formulation permits arbitrary temporal…

Disordered Systems and Neural Networks · Physics 2007-05-23 John Hertz , Barry Richmond , Kristian Nilsen

The theta rhythm is important for many cognitive functions including spatial processing, memory encoding, and memory recall. The information processing underlying these functions is thought to rely on consistent, phase-specific spiking…

Neurons and Cognition · Quantitative Biology 2025-10-16 Oleg Makarenkov , Marianne Bezaire , Michael Hasselmo

A central challenge in the computational modeling of neural dynamics is the trade-off between accuracy and simplicity. At the level of individual neurons, nonlinear dynamics are both experimentally established and essential for neuronal…

Recent developments in the interfacing of neurons with silicon chips may pave the way for progress in constructing scalable neurocomputers. The assembly of synthetic neuronal networks with predefined synaptic connections and controlled…

Neurons and Cognition · Quantitative Biology 2009-01-16 Nikesh S. Dattani

Sensitive dependence of nonlinear systems on initial conditions or parameters can be useful in applications. We propose in this paper that bubbling behavior in simple driven symmetrical maps may be used as a working principle of sensitive…

Chaotic Dynamics · Physics 2007-05-23 Changsong Zhou , C. -H. Lai

This paper investigates the controllability of a broad class of recurrent neural networks widely used in theoretical neuroscience, including models of large-scale human brain dynamics. Motivated by emerging applications in non-invasive…

Optimization and Control · Mathematics 2025-09-29 Cyprien Tamekue , Ruiqi Chen , ShiNung Ching

In this paper we present a simple microscopic stochastic model describing short term plasticity within a large homogeneous network of interacting neurons. Each neuron is represented by its membrane potential and by the residual calcium…

Probability · Mathematics 2020-01-29 Antonio Galves , Eva Löcherbach , Christophe Pouzat , Errico Presutti

While it is common practice in applied network analysis to report various standard network summary statistics, these numbers are rarely accompanied by uncertainty quantification. Yet any error inherent in the measurements underlying the…

Methodology · Statistics 2022-05-06 Jinyuan Chang , Eric D. Kolaczyk , Qiwei Yao

A simple one-dimensional mechanical model is proposed for splitting instability in swollen membranes. The splitting instability occurs by ring constriction. The bifurcation can be both subcritical and supercritical, depending on the…

Soft Condensed Matter · Physics 2015-06-18 Hidetsugu Sakaguchi , Satomi Maeyama