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Modern deep neural networks achieved remarkable progress in medical image segmentation tasks. However, it has recently been observed that they tend to produce overconfident estimates, even in situations of high uncertainty, leading to…

Computer Vision and Pattern Recognition · Computer Science 2023-06-05 Agostina Larrazabal , Cesar Martinez , Jose Dolz , Enzo Ferrante

Electron ptychography provides new opportunities to resolve atomic structures with deep sub-angstrom spatial resolution and studying electron-beam sensitive materials with high dose efficiency. In practice, obtaining accurate ptychography…

Materials Science · Physics 2022-04-26 Michael C. Cao , Zhen Chen , Yi Jiang , Yimo Han

This paper studies a new unmanned aerial vehicle (UAV)-enabled wireless power transfer (WPT) system, where a UAV-mounted energy transmitter (ET) broadcasts wireless energy to charge distributed energy receivers (ERs) on the ground. In…

Information Theory · Computer Science 2017-06-22 Jie Xu , Yong Zeng , Rui Zhang

Unknown electric conductivities of human tissues is a common issue in medical engineering. Electrical impedance tomography (EIT) is an imaging modality that can be used to determine these conductivities in vivo from boundary measurements.…

Medical Physics · Physics 2020-02-03 Ville Rimpilainen , Theodoros Samaras , Alexandra Koulouri

We present numerical experiments for geophysics electromagnetic (EM) modeling based upon high-order edge elements and supervised $h+p$ refinement approaches on massively parallel computers. Our high-order $h+p$ refinement strategy is based…

Purpose: Commercial UHDR platforms deliver Ultra-High Dose Rate (UHDR) doses at discrete combinations of pulse parameters including pulse width (PW), pulse repetition frequency (PRF) and number of pulses (N), which dictate unique…

Elastic MicroPhase Separation (EMPS) provides a simple route to create soft materials with homogeneous microstructures by leveraging the supersaturation of crosslinked polymer networks with liquids. At low supersaturation, network…

When generating in-silico clinical electrophysiological outputs, such as electrocardiograms (ECGs) and body surface potential maps (BSPMs), mathematical models have relied on single physics, i.e. of the cardiac electrophysiology (EP),…

Numerical Analysis · Mathematics 2024-02-12 Elena Zappon , Matteo Salvador , Roberto Piersanti , Francesco Regazzoni , Luca Dede' , Alfio Quarteroni

In this article, a new conceptual biomedical engineering strategy to tackle modern disease challenges, termed as liquid metal enabled electrobiology, is proposed. This generalized and easy going way is based on the physiological fact that…

Medical Physics · Physics 2018-05-11 Xuelin Wang , Yi Ren , Jing Liu

In this paper, we present a molecular theory analysis of ions and potential distribution, degree of ionization of polyelectrolyte (PE) brushes, velocity profile, volumetric flow rate, ionic selectivity, ionic conduction and advection by…

Soft Condensed Matter · Physics 2020-07-01 Milad Reshadi , Mohammad Hassan Saidi

The interaction between a linear electron beam and a guided electromagnetic wave is studied in the contest of exceptional points of degeneracy (EPD) supported by such an interactive system. The study focuses on the case of a linear beam…

We consider a dose-optimization design for first-in-human oncology trial that aims to identify a suitable dose for late-phase drug development. The proposed approach, called the Pharmacometrics-Enabled DOse OPtimization (PEDOOP) design,…

Applications · Statistics 2024-06-19 Shijie Yuan , Zhanbo Huang , Jiaxin Liu , Yuan Ji

In recent years, extracellular vesicles such have become promising carriers as the next-generation drug delivery platforms. Effective loading of exogenous cargos without compromising the extracellular vesicle membrane is a major challenge.…

Biomolecules · Quantitative Biology 2023-04-14 Khayrul Islam , Meghdad Razizadeh , Yaling Liu

Cortical visual prostheses aim to restore sight by electrically stimulating neurons in early visual cortex (V1). With the emergence of high-density and flexible neural interfaces, electrode placement within three-dimensional cortex has…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Galen Pogoncheff , Alvin Wang , Jacob Granley , Michael Beyeler

This paper presents novel extremum seeking (ES) strategies for maximum power point tracking (MPPT) in photovoltaic (PV) systems that ensure unbiased convergence and prescribed-time performance. Conventional ES methods suffer from…

Optimization and Control · Mathematics 2025-10-08 Cemal Tugrul Yilmaz , Eric Foss , Mamadou Diagne , Miroslav Krstic

An essential ingredient of a spectral method is the choice of suitable bases for test and trial spaces. On complex domains, these bases are harder to devise, necessitating the use of domain partitioning techniques such as the spectral…

Numerical Analysis · Mathematics 2021-11-17 Saad Qadeer , Ehssan Nazockdast , Boyce E. Griffith

Tumor Treating Fields (TTFields) is a non-invasive anticancer modality that utilizes alternating electric fields to disrupt cancer cell division and growth. While generally well-tolerated with minimal side effects, traditional TTFields…

Medical Physics · Physics 2024-07-11 Minmin Wang , Xu Xie , Yuxi Guo , Liying Zhu , Yue Lan , Haitang Yang , Yun Pan , Guangdi Chen , Shaomin Zhang , Maomao Zhang

Finding the stopping site of the muon in a muon-spin relaxation experiment is one of the main problems of muon spectroscopy, and computational techniques that make use of quantum chemistry simulations can be of great help when looking for…

Materials Science · Physics 2020-08-26 Simone Sturniolo , Leandro Liborio

The parametric optimization for the ultrasound computed tomography system is introduced. It is hypothesized that the pulse characteristic directly affects the information present in the reconstructed profile. The ultrasound excitation modes…

Medical Physics · Physics 2024-08-13 Ankur Kumar , Mayank Goswami

Chronic neck pain is a leading cause of disability worldwide, and current treatment selection remains largely trial and error. We present a machine learning framework that uses electroencephalography to predict treatment efficacy in…

Quantitative Methods · Quantitative Biology 2026-05-19 Xiru Wang , Aiden Li , Hongzhao Tan , Stevie Foglia , Aimee Nelson , Zhen Gao
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