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In this paper, the complete synchronization problem of linearly coupled neural networks with reaction-diffusion terms and time-varying delays via aperiodically intermittent pinning control is investigated. The coupling matrix for the…

Systems and Control · Computer Science 2016-04-13 Xiwei Liu , Zhang Chen , Lingjun Zhou

Feed-forward loops (FFLs) are among the most ubiquitously found motifs of reaction networks in nature. However, little is known about their stochastic behavior and the variety of network phenotypes they can exhibit. In this study, we…

Molecular Networks · Quantitative Biology 2021-04-08 Anna Terebus , Farid Manuchehrfar , Youfang Cao , Jie Liang

Dynamic force spectroscopy (DFS) is an experimental technique that is commonly used to assess information of the strength, energy landscape, and lifetime of noncovalent bio-molecular interactions. DFS traditionally requires an applied force…

Biological Physics · Physics 2016-07-04 Oscar Björnham , Magnus Andersson

Multistationarity - the existence of multiple equilibrium points - is a common phenomenon in dynamical systems from a variety of fields, including neuroscience, opinion dynamics, systems biology, and power systems. A recently proposed…

Systems and Control · Electrical Eng. & Systems 2024-08-26 Ron Ofir , Francesco Bullo , Michael Margaliot

We consider nonlinear effects in scattering of light by a periodic structure supporting optical bound states in the continuum. In the spectral vicinity of the bound states the scattered electromagnetic field is resonantly enhanced…

Optics · Physics 2019-02-18 Evgeny N. Bulgakov , Dmitrii N. Maksimov

Randomly-connected networks of integrate-and-fire (IF) neurons are known to display asynchronous irregular (AI) activity states, which resemble the discharge activity recorded in the cerebral cortex of awake animals. However, it is not…

Neurons and Cognition · Quantitative Biology 2009-10-27 Alain Destexhe

In this paper we consider a delayed nonlinear model of the dynamics of the immune system against a viral infection that contains wild-type virus and one mutant. A finite response time of the immune system was considered in order which leads…

Populations and Evolution · Quantitative Biology 2017-11-22 D. Messias , Iram Gleria , S. S. Albuquerque , Askery Canabarro , H. E. Stanley

Activity in neocortex exhibits a range of behaviors, from irregular to temporally precise, and from weakly to strongly correlated. So far there has been no single theoretical framework that could explain all these behaviors, leaving open…

Neurons and Cognition · Quantitative Biology 2015-11-03 Alexander Lerchner , Peter E. Latham

Signal transduction within biological cells is governed by networks of interacting proteins. Communication between these proteins is mediated by signaling molecules which bind to receptors and induce stochastic transitions between different…

Molecular Networks · Quantitative Biology 2017-04-05 Gonzalo Hernandez-Hernandez , Jesse Myers , Enric Alvarez-Lacalle , Yohannes Shiferaw

We present a detailed study of a scalar differential equation with threshold state-dependent delayed feedback. This equation arises as a simplification of a gene regulatory model. There are two monotone nonlinearities in the model: one…

Dynamical Systems · Mathematics 2025-04-29 Tomas Gedeon , Antony R. Humphries , Michael C. Mackey , Hans-Otto Walther , Zhao Wang

Linear mixed models are widely used to analyze non-independent data, but inference for fixed effects can be unreliable under misspecification of the random-effects distribution, inaccurate Fisher information estimation, or convergence…

Methodology · Statistics 2026-05-01 Angela Andreella , Livio Finos

Synchronizability of stable, output-coupled, identical, time-varying linear systems is studied. It is shown that if the observability grammian satisfies a persistence of excitation condition, then there exists a bounded, time-varying linear…

Dynamical Systems · Mathematics 2008-11-24 S. Emre Tuna

Cellular decision-making (CDM) is a dynamic phenomenon often controlled by regulatory networks defining interactions between genes and transcription factor proteins. Traditional studies have focussed on molecular switches such as positive…

Molecular Networks · Quantitative Biology 2024-04-09 Akriti Srivastava , Mubasher Rashid

We give necessary conditions for when a subset of $\mathbb{T}^n$ can contain the support of some non-zero RP-measure. Among other things we show that the support of a positive RP-measure cannot be contained in reflections of inverse images…

Complex Variables · Mathematics 2023-04-07 Linus Bergqvist

How biological networks achieve robust control despite relying on imperfect, local information remains an important open question. Here, we identify thermodynamic constraints that can curtail non-equilibrium steady-state responses so…

Statistical Mechanics · Physics 2026-05-27 Carlos Floyd , Aaron R. Dinner , Suriyanarayanan Vaikuntanathan

Non-ergodic renewal processes have recently been shown by several authors to be insensitive to periodic perturbations, thereby apparently sanctioning the death of linear response, a building block of nonequilibrium statistical physics. We…

Statistical Mechanics · Physics 2015-05-19 Gerardo Aquino , Mauro Bologna , Paolo Grigolini , Bruce J. West

This paper is devoted to reaction-diffusion equations with bistable nonlinearities depending periodically on time. These equations admit two linearly stable states. However, the reaction terms may not be bistable at every time. These may…

Analysis of PDEs · Mathematics 2015-07-23 Benjamin Contri

In mathematical biology and the theory of electric networks the firing map of an integrate-and-fire system is a notion of importance. In order to prove useful properties of this map authors of previous papers assumed that the stimulus…

Dynamical Systems · Mathematics 2011-06-17 W. Marzantowicz , J. Signerska

Various social, financial, biological and technological systems can be modeled by interdependent networks. It has been assumed that in order to remain functional, nodes in one network must receive the support from nodes belonging to…

Physics and Society · Physics 2017-12-01 M. A. Di Muro , L. D. Valdez , H. H. A. Rêgo , S. V. Buldyrev , H. E. Stanley , L. A. Braunstein

Determining conditions on the coupling strength for the synchronization in networks of interconnected oscillators is a challenging problem in nonlinear dynamics. While sophisticated mathematical methods have been used to derive conditions,…

Systems and Control · Electrical Eng. & Systems 2026-04-21 Sanjeev Kumar Pandey , Shaunak Sen , Indra Narayan Kar