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The ability to understand visual information from limited labeled data is an important aspect of machine learning. While image-level classification has been extensively studied in a semi-supervised setting, dense pixel-level classification…

Computer Vision and Pattern Recognition · Computer Science 2019-08-19 Sudhanshu Mittal , Maxim Tatarchenko , Thomas Brox

Introspection of deep supervised predictive models trained on functional and structural brain imaging may uncover novel markers of Alzheimer's disease (AD). However, supervised training is prone to learning from spurious features (shortcut…

Machine Learning · Computer Science 2022-05-24 Alex Fedorov , Lei Wu , Tristan Sylvain , Margaux Luck , Thomas P. DeRamus , Dmitry Bleklov , Sergey M. Plis , Vince D. Calhoun

The integration of diverse clinical modalities such as medical imaging and the tabular data extracted from patients' Electronic Health Records (EHRs) is a crucial aspect of modern healthcare. Integrative analysis of multiple sources can…

Computer Vision and Pattern Recognition · Computer Science 2025-04-22 Daniel Duenias , Brennan Nichyporuk , Tal Arbel , Tammy Riklin Raviv

Alzheimer's Disease is a progressive neurological disorder that is one of the most common forms of dementia. It leads to a decline in memory, reasoning ability, and behavior, especially in older people. The cause of Alzheimer's Disease is…

Machine Learning · Computer Science 2025-04-03 Jing Wang , Jun-En Ding , Feng Liu , Elisa Kallioniemi , Shuqiang Wang , Wen-Xiang Tsai , Albert C. Yang

Semi-supervised learning is increasingly popular in medical image segmentation due to its ability to leverage large amounts of unlabeled data to extract additional information. However, most existing semi-supervised segmentation methods…

Computer Vision and Pattern Recognition · Computer Science 2024-08-19 Rong Wu , Dehua Li , Cong Zhang

Automated semantic segmentation of cell nuclei in microscopic images is crucial for disease diagnosis and tissue microenvironment analysis. Nonetheless, this task presents challenges due to the complexity and heterogeneity of cells. While…

Image and Video Processing · Electrical Eng. & Systems 2023-08-10 Zhuchen Shao , Sourya Sengupta , Hua Li , Mark A. Anastasio

When modeling class-imbalanced data, it is crucial to address the imbalance, as models trained on such data tend to be biased towards the majority classes. This problem is amplified under partial supervision, where pseudo-labels for…

Machine Learning · Statistics 2026-05-08 Heegeon Yoon , Heeyoung Kim

Graph-based semi-supervised learning usually involves two separate stages, constructing an affinity graph and then propagating labels for transductive inference on the graph. It is suboptimal to solve them independently, as the correlation…

Computer Vision and Pattern Recognition · Computer Science 2019-02-19 Qilin Li , Senjian An , Ling Li , Wanquan Liu

In diagnosing challenging conditions such as Alzheimer's disease (AD), imaging is an important reference. Non-imaging patient data such as patient information, genetic data, medication information, cognitive and memory tests also play a…

Machine Learning · Computer Science 2023-06-01 Yingjie Feng , Jun Wang , Xianfeng Gu , Xiaoyin Xu , Min Zhang

In order to find effective treatments for Alzheimer's disease (AD), we need to identify subjects at risk of AD as early as possible. To this end, recently developed disease progression models can be used to perform early diagnosis, as well…

Quantitative Methods · Quantitative Biology 2020-03-11 Razvan V. Marinescu

Alzheimer's disease (AD) diagnosis requires integrating neuroimaging with heterogeneous clinical evidence and reasoning under established criteria, yet most multimodal models remain opaque and weakly guideline-aligned. We present…

Computer Vision and Pattern Recognition · Computer Science 2026-03-26 Qiuhui Chen , Yushan Deng , Xuancheng Yao , Yi Hong

Recent advances in semi-supervised learning methods rely on estimating the categories of unlabeled data using a model trained on the labeled data (pseudo-labeling) and using the unlabeled data for various consistency-based regularization.…

Machine Learning · Computer Science 2019-06-14 Chia-Wen Kuo , Chih-Yao Ma , Jia-Bin Huang , Zsolt Kira

The success of supervised deep learning models on cell recognition tasks relies on detailed annotations. Many previous works have managed to reduce the dependency on labels. However, considering the large number of cells contained in a…

Computer Vision and Pattern Recognition · Computer Science 2023-08-23 Pingyi Chen , Chenglu Zhu , Zhongyi Shui , Jiatong Cai , Sunyi Zheng , Shichuan Zhang , Lin Yang

Graph Neural Networks (GNNs) have achieved state-of-the-art results for semi-supervised node classification on graphs. Nevertheless, the challenge of how to effectively learn GNNs with very few labels is still under-explored. As one of the…

Machine Learning · Computer Science 2022-01-21 Yayong Li , Jie Yin , Ling Chen

Alzheimer's disease is a neurogenerative disease that alters memories, cognitive functions leading to death. Early diagnosis of the disease, by detection of the preliminary stage, called Mild Cognitive Impairment (MCI), remains a…

Image and Video Processing · Electrical Eng. & Systems 2020-12-03 Achraf Ben Miled , Taoufik Yeferny , Amira ben Rabeh

Early and reliable detection of Alzheimer's disease (AD) is crucial for timely clinical intervention and improved patient management. It also supports the evaluation of emerging therapeutic strategies. In this paper, we propose a Low-Rank…

Machine Learning · Computer Science 2026-05-07 Wu Wang , Yuang Cheng , Fouzi Harrou , Ying Sun

Diabetic Retinopathy (DR) is a significant cause of blindness globally, highlighting the urgent need for early detection and effective treatment. Recent advancements in Machine Learning (ML) techniques have shown promise in DR detection,…

Computer Vision and Pattern Recognition · Computer Science 2023-09-06 D. Dhinakaran , L. Srinivasan , D. Selvaraj , S. M. Udhaya Sankar

Accurate and efficient classification of Alzheimer's disease (AD) severity from brain magnetic resonance imaging (MRI) remains a critical challenge, particularly when limited data and model interpretability are of concern. In this work, we…

Computer Vision and Pattern Recognition · Computer Science 2026-01-06 Faisal Ahmed

Normative modelling is an emerging method for understanding the underlying heterogeneity within brain disorders like Alzheimer Disease (AD) by quantifying how each patient deviates from the expected normative pattern that has been learned…

Image and Video Processing · Electrical Eng. & Systems 2026-02-06 Sayantan Kumar , Philip Payne , Aristeidis Sotiras

The progress in hyperbolic neural networks (HNNs) research is hindered by their absence of inductive bias mechanisms, which are essential for generalizing to new tasks and facilitating scalable learning over large datasets. In this paper,…

Machine Learning · Computer Science 2023-10-31 Nurendra Choudhary , Nikhil Rao , Chandan K. Reddy