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Photon counting CT (PCCT) has been a research focus in the last two decades. Recent studies and advancements have demonstrated that systems using semiconductor-based photon counting detectors (PCDs) have the potential to provide better…

Breast CT provides image volumes with isotropic resolution in high contrast, enabling detection of small calcification (down to a few hundred microns in size) and subtle density differences. Since breast is sensitive to x-ray radiation,…

Image and Video Processing · Electrical Eng. & Systems 2020-11-05 Huidong Xie , Hongming Shan , Wenxiang Cong , Chi Liu , Xiaohua Zhang , Shaohua Liu , Ruola Ning , Ge Wang

Purpose: Cone-beam CT (CBCT) plays an important role in image guided radiation therapy (IGRT). However, the large radiation dose from serial CBCT scans in most IGRT procedures raises a clinical concern, especially for pediatric patients who…

Medical Physics · Physics 2015-05-18 Xun Jia , Yifei Lou , Ruijiang Li , William Y. Song , Steve B. Jiang

Low dose CT is of great interest in these days. Dose reduction raises noise level in projections and decrease image quality in reconstructions. Model based image reconstruction can combine statistical noise model together with prior…

Medical Physics · Physics 2019-10-16 Kaichao Liang , Li Zhang , Yirong Yang , HongKai Yang , Yuxiang Xing

Synchrotron radiation sources are widely used in various fields, among which computed tomography (CT) is one of the most important. The amount of effort expended by the operator varies depending on the subject. If the number of angles…

Image and Video Processing · Electrical Eng. & Systems 2021-09-08 Ling Li , Yu Hu

Low dose X-ray computed tomography (LDCT) is desirable for reduced patient dose. This work develops image reconstruction methods with deep learning (DL) regularization for LDCT. Our methods are based on unrolling of proximal…

Image and Video Processing · Electrical Eng. & Systems 2020-08-26 Qiaoqiao Ding , Gaoyu Chen , Xiaoqun Zhang , Qiu Huang , Hui Jiand Hao Gao

The development of fast and accurate image reconstruction algorithms is a central aspect of computed tomography. In this paper, we investigate this issue for the sparse data problem in photoacoustic tomography (PAT). We develop a direct and…

Computer Vision and Pattern Recognition · Computer Science 2018-08-31 Stephan Antholzer , Markus Haltmeier , Johannes Schwab

Deep learning has emerged as a powerful artificial intelligence tool to interpret medical images for a growing variety of applications. However, the paucity of medical imaging data with high-quality annotations that is necessary for…

Computer Vision and Pattern Recognition · Computer Science 2018-10-02 Faisal Mahmood , Richard Chen , Sandra Sudarsky , Daphne Yu , Nicholas J. Durr

Long lasting efforts have been made to reduce radiation dose and thus the potential radiation risk to the patient for computed tomography acquisitions without severe deterioration of image quality. To this end, numerous reconstruction and…

Medical Physics · Physics 2024-10-07 Elias Eulig , Björn Ommer , Marc Kachelrieß

Quantitative imaging is an important feature of spectral X-ray and CT systems, especially photon-counting CT (PCCT) imaging systems, which is achieved through material decomposition (MD) using spectral measurements. In this work, we present…

Medical Physics · Physics 2026-03-04 Sen Wang , Yirong Yang , Jooho Lee , Grant M. Stevens , Adam S. Wang

Attenuation correction is an essential requirement of positron emission tomography (PET) image reconstruction to allow for accurate quantification. However, attenuation correction is particularly challenging for PET-MRI as neither PET nor…

Low Dose Computed Tomography (LDCT) has offered tremendous benefits in radiation restricted applications, but the quantum noise as resulted by the insufficient number of photons could potentially harm the diagnostic performance. Current…

Computer Vision and Pattern Recognition · Computer Science 2019-03-06 Xin Yi , Paul Babyn

Deep learning based computed tomography (CT) reconstruction has demonstrated outstanding performance on simulated 2D low-dose CT data. This applies in particular to domain adapted neural networks, which incorporate a handcrafted physics…

Image and Video Processing · Electrical Eng. & Systems 2023-11-30 Jevgenija Rudzusika , Buda Bajić , Thomas Koehler , Ozan Öktem

Deep learning-based reconstruction of positron emission tomography(PET) data has gained increasing attention in recent years. While these methods achieve fast reconstruction,concerns remain regarding quantitative accuracy and the presence…

This study aims to improve photon counting CT (PCCT) image resolution using denoising diffusion probabilistic models (DDPM). Although DDPMs have shown superior performance when applied to various computer vision tasks, their effectiveness…

Computer Vision and Pattern Recognition · Computer Science 2024-08-29 Chuang Niu , Christopher Wiedeman , Mengzhou Li , Jonathan S Maltz , Ge Wang

Computed Tomography (CT) takes X-ray measurements on the subjects to reconstruct tomographic images. As X-ray is radioactive, it is desirable to control the total amount of dose of X-ray for safety concerns. Therefore, we can only select a…

Medical Physics · Physics 2021-09-15 Ziju Shen , Yufei Wang , Dufan Wu , Xu Yang , Bin Dong

This paper applies the recent fast iterative neural network framework, Momentum-Net, using appropriate models to low-dose X-ray computed tomography (LDCT) image reconstruction. At each layer of the proposed Momentum-Net, the model-based…

Image and Video Processing · Electrical Eng. & Systems 2020-09-10 Siqi Ye , Yong Long , Il Yong Chun

Spectral computed tomography (CT) is an emerging technology capable of providing high chemical specificity, which is crucial for many applications such as detecting threats in luggage. This type of application requires both fast and…

Image and Video Processing · Electrical Eng. & Systems 2021-03-30 Wail Mustafa , Christian Kehl , Ulrik Lund Olsen , Søren Kimmer Schou Gregersen , David Malmgren-Hansen , Jan Kehres , Anders Bjorholm Dahl

Cone beam computed tomography (CBCT)-guided puncture has become an established approach for diagnosing and treating early- to mid-stage thoracic tumours, yet the associated radiation exposure substantially elevates the risk of secondary…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Haoshen Wang , Lei Chen , Wei-Hua Zhang , Linxia Wu , Yong Luo , Zengmao Wang , Yuan Xiong , Chengcheng Zhu , Wenjuan Tang , Xueyi Zhang , Wei Zhou , Xuhua Duan , Lefei Zhang , Gao-Jun Teng , Bo Du , Huangxuan Zhao

Accurate segmentation of the pelvic CTs is crucial for the clinical diagnosis of pelvic bone diseases and for planning patient-specific hip surgeries. With the emergence and advancements of deep learning for digital healthcare, several…

Image and Video Processing · Electrical Eng. & Systems 2021-01-28 Prabhakara Subramanya Jois , Aniketh Manjunath , Thomas Fevens