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Coronary angiography remains the gold standard for diagnosis of coronary artery disease, the most common cause of death worldwide. While this procedure is performed more than 2 million times annually, there remain few methods for fast and…

Image and Video Processing · Electrical Eng. & Systems 2023-10-25 Tom Liu , Hui Lin , Aggelos K. Katsaggelos , Adrienne Kline

Deep learning based approaches to Computer Aided Diagnosis (CAD) typically pose the problem as an image classification (Normal or Abnormal) problem. These systems achieve high to very high accuracy in specific disease detection for which…

Computer Vision and Pattern Recognition · Computer Science 2020-10-06 Aniket Joshi , Gaurav Mishra , Jayanthi Sivaswamy

Providing closed and well-connected boundaries of coronary artery is essential to assist cardiologists in the diagnosis of coronary artery disease (CAD). Recently, several deep learning-based methods have been proposed for boundary…

Stroke is the second leading cause of disability worldwide. In order to minimize disability, the goal of stroke treatment is to preserve tissue in the area where blood supply is decreased but sufficient to stave off cell death. Thrombectomy…

Cardiac diseases are among the leading causes of morbidity and mortality worldwide, which requires accurate and timely diagnostic strategies. In this study, we introduce an innovative approach that combines deep learning image registration…

Machine Learning · Computer Science 2025-07-09 Comte Valentin , Gemma Piella , Mario Ceresa , Miguel A. Gonzalez Ballester

Early diagnosis of acute coronary artery occlusion based on electrocardiogram (ECG) findings is essential for prompt delivery of primary percutaneous coronary intervention. Current ST elevation (STE) criteria are specific but insensitive.…

Cardiac Magnetic Resonance (CMR) is the most effective tool for the assessment and diagnosis of a heart condition, which malfunction is the world's leading cause of death. Software tools leveraging Artificial Intelligence already enhance…

Computer Vision and Pattern Recognition · Computer Science 2021-03-16 Adrianna Janik , Jonathan Dodd , Georgiana Ifrim , Kris Sankaran , Kathleen Curran

Coronary artery disease (CAD) remains the world's leading cause of mortality and the disease burden is continually expanding as the population ages. Recently, the MR-INFORM randomised trial has demonstrated that the management of patients…

Image and Video Processing · Electrical Eng. & Systems 2021-05-12 Cian M Scannell

Coronary artery disease (CAD) is one of the primary causes leading deaths worldwide. The presence of atherosclerotic lesions in coronary arteries is the underlying pathophysiological basis of CAD, and accurate extraction of individual…

Computer Vision and Pattern Recognition · Computer Science 2023-12-22 Chen Zhao , Zhihui Xu , Guang-Uei Hung , Weihua Zhou

The development of machine learning systems for the diagnosis of rare diseases is challenging mainly due the lack of data to study them. Despite this challenge, this paper proposes a system for the Computer Aided Diagnosis (CAD) of…

Computer Vision and Pattern Recognition · Computer Science 2019-02-01 Adrián Bazaga , Mònica Roldán , Carmen Badosa , Cecilia Jiménez-Mallebrera , Josep M. Porta

Cardiovascular disease (CVD) is a leading cause of death in the lung cancer screening population. Chest CT scans made in lung cancer screening are suitable for identification of participants at risk of CVD. Existing methods analyzing CT…

Computer Vision and Pattern Recognition · Computer Science 2018-10-05 Sanne G. M. van Velzen , Majd Zreik , Nikolas Lessmann , Max A. Viergever , Pim A. de Jong , Helena M. Verkooijen , Ivana Išgum

Background: Extensive clinical evidence suggests that a preventive screening of coronary heart disease (CHD) at an earlier stage can greatly reduce the mortality rate. We use 64 two-dimensional speckle tracking echocardiography (2D-STE)…

Machine Learning · Statistics 2021-05-21 Jingyi Zhang , Huolan Zhu , Yongkai Chen , Chenguang Yang , Huimin Cheng , Yi Li , Wenxuan Zhong , Fang Wang

Cardiovascular disease (CVD) accounts for about half of non-communicable diseases. Vessel stenosis in the coronary artery is considered to be the major risk of CVD. Computed tomography angiography (CTA) is one of the widely used noninvasive…

Image and Video Processing · Electrical Eng. & Systems 2023-10-18 An Zeng , Chunbiao Wu , Meiping Huang , Jian Zhuang , Shanshan Bi , Dan Pan , Najeeb Ullah , Kaleem Nawaz Khan , Tianchen Wang , Yiyu Shi , Xiaomeng Li , Guisen Lin , Xiaowei Xu

Various types of atherosclerotic plaque and varying grades of stenosis could lead to different management of patients with coronary artery disease. Therefore, it is crucial to detect and classify the type of coronary artery plaque, as well…

Computer Vision and Pattern Recognition · Computer Science 2018-12-11 Majd Zreik , Robbert W. van Hamersvelt , Jelmer M. Wolterink , Tim Leiner , Max A. Viergever , Ivana Isgum

Coronary angiography continues to serve as the primary method for diagnosing coronary artery disease (CAD), which is the leading global cause of mortality. The severity of CAD is quantified by the location, degree of narrowing (stenosis),…

Image and Video Processing · Electrical Eng. & Systems 2023-10-24 Hui Lin , Tom Liu , Aggelos Katsaggelos , Adrienne Kline

Traditionally, medical discoveries are made by observing associations and then designing experiments to test these hypotheses. However, observing and quantifying associations in images can be difficult because of the wide variety of…

Computer Vision and Pattern Recognition · Computer Science 2020-06-19 Ryan Poplin , Avinash V. Varadarajan , Katy Blumer , Yun Liu , Michael V. McConnell , Greg S. Corrado , Lily Peng , Dale R. Webster

Coronary artery disease leading up to stenosis, the partial or total blocking of coronary arteries, is a severe condition that affects millions of patients each year. Automated identification and classification of stenosis severity from…

Image and Video Processing · Electrical Eng. & Systems 2021-03-05 Dinis L. Rodrigues , Miguel Nobre Menezes , Fausto J. Pinto , Arlindo L. Oliveira

Current clinical practice guidelines for managing Coronary Artery Disease (CAD) account for general cardiovascular risk factors. However, they do not present a framework that considers personalized patient-specific characteristics. Using…

Machine Learning · Statistics 2019-10-21 Dimitris Bertsimas , Agni Orfanoudaki , Rory B. Weiner

Coronary heart disease (CHD) remains a leading cause of mortality worldwide. This study introduces a novel approach that integrates patient-specific Multi-slice CT scans into CAD models, using a one-dimensional numerical framework to assess…

Medical Physics · Physics 2025-05-21 Priyanshu Ghosh , Sayan Karmakar , Disha Mondal , Oeshee Roy , Supratim Saha

Assessing coronary artery plaque segments in coronary CT angiography scans is an important task to improve patient management and clinical outcomes, as it can help to decide whether invasive investigation and treatment are necessary. In…