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We present a deep neural network to reduce coherent noise in three-dimensional quantitative phase imaging. Inspired by the cycle generative adversarial network, the denoising network was trained to learn a transform between two image…

Single-shot X-ray imaging of short-lived nanostructures such as clusters and nanoparticles near a phase transition or non-crystalizing objects such as large proteins and viruses is currently the most elegant method for characterizing their…

Atomic and Molecular Clusters · Physics 2020-10-14 Thomas Stielow , Robin Schmidt , Christian Peltz , Thomas Fennel , Stefan Scheel

A deep convolutional neural network has been developed to denoise atomic-resolution TEM image datasets of nanoparticles acquired using direct electron counting detectors, for applications where the image signal is severely limited by shot…

Atomic resolution electron microscopy, particularly high-angle annular dark-field scanning transmission electron microscopy, has become an essential tool for many scientific fields, when direct visualization of atomic arrangements and…

We present an application of autoencoders to the problem of noise reduction in single-shot astronomical images and explore its suitability for upcoming large-scale surveys. Autoencoders are a machine learning model that summarises an input…

Instrumentation and Methods for Astrophysics · Physics 2023-03-08 Oliver. J. Bartlett , David. M. Benoit , Kevin. A. Pimbblet , Brooke Simmons , Laura Hunt

In this paper, we introduce a new architecture for few shot learning, the task of teaching a neural network from as few as one or five labeled examples. Inspired by the theoretical results of Alaine et al that Denoising Autoencoders refine…

Computer Vision and Pattern Recognition · Computer Science 2021-10-27 Steven Schwarcz , Sai Saketh Rambhatla , Rama Chellappa

We report the development of deep learning coherent electron diffractive imaging at sub-angstrom resolution using convolutional neural networks (CNNs) trained with only simulated data. We experimentally demonstrate this method by applying…

Materials Science · Physics 2022-04-19 Dillan J. Chang , Colum M. O'Leary , Cong Su , Salman Kahn , Alex Zettl , Jim Ciston , Peter Ercius , Jianwei Miao

Intense short-wavelength pulses from free-electron lasers and high-harmonic-generation sources enable diffractive imaging of individual nano-sized objects with a single x-ray laser shot. The enormous data sets with up to several million…

Ultrafast electron beam X-ray computed tomography produces noisy data due to short measurement times, causing reconstruction artifacts and limiting overall image quality. To counteract these issues, two self-supervised deep learning methods…

Machine Learning · Computer Science 2025-11-24 Israt Jahan Tulin , Sebastian Starke , Dominic Windisch , André Bieberle , Peter Steinbach

We investigated the use of a U-Net convolutional neural network for denoising simulated medium-resolution spectroscopic observations of stars. Simulated spectra were generated under realistic observational conditions resembling the Subaru…

Instrumentation and Methods for Astrophysics · Physics 2025-04-04 Balázs Pál , László Dobos

Deep learning-based super-resolution models have the potential to revolutionize biomedical imaging and diagnoses by effectively tackling various challenges associated with early detection, personalized medicine, and clinical automation.…

Medical Physics · Physics 2023-06-27 Yuanzheng Ma , Xinyue Wang , Benqi Zhao , Ying Xiao , Shijie Deng , Jian Song , Xun Guan

Single particle imaging (SPI) at X-ray free electron lasers (XFELs) is particularly well suited to determine the 3D structure of particles in their native environment. For a successful reconstruction, diffraction patterns originating from a…

Data Analysis, Statistics and Probability · Physics 2021-12-17 Dameli Assalauova , Alexandr Ignatenko , Fabian Isensee , Sergey Bobkov , Darya Trofimova , Ivan A. Vartanyants

In recent years, deep learning-based image compression, particularly through generative models, has emerged as a pivotal area of research. Despite significant advancements, challenges such as diminished sharpness and quality in…

Image and Video Processing · Electrical Eng. & Systems 2024-09-18 Ryugo Morita , Hitoshi Nishimura , Ko Watanabe , Andreas Dengel , Jinjia Zhou

Speckle noise has long been an extensively studied problem in medical imaging. In recent years, there have been significant advances in leveraging deep learning methods for noise reduction. Nevertheless, adaptation of supervised learning…

Image and Video Processing · Electrical Eng. & Systems 2023-06-21 Deborah Pereg

Current self-supervised denoising methods for paired noisy images typically involve mapping one noisy image through the network to the other noisy image. However, after measuring the spectral bias of such methods using our proposed Image…

Computer Vision and Pattern Recognition · Computer Science 2025-10-02 Wang Zhang , Huaqiu Li , Xiaowan Hu , Tao Jiang , Zikang Chen , Haoqian Wang

Noise is an important issue for radiographic and tomographic imaging techniques. It becomes particularly critical in applications where additional constraints force a strong reduction of the Signal-to-Noise Ratio (SNR) per image. These…

Computer Vision and Pattern Recognition · Computer Science 2023-03-28 Yaroslav Zharov , Evelina Ametova , Rebecca Spiecker , Tilo Baumbach , Genoveva Burca , Vincent Heuveline

Single-shot wide-angle diffraction imaging is a widely used method to investigate the structure of non-crystallizing objects such as nanoclusters, large proteins or even viruses. Its main advantage is that information about the…

Data Analysis, Statistics and Probability · Physics 2021-06-02 Thomas Stielow , Stefan Scheel

Recent advances in deep learning have led to significant improvements in single image super-resolution (SR) research. However, due to the amplification of noise during the upsampling steps, state-of-the-art methods often fail at…

Computer Vision and Pattern Recognition · Computer Science 2021-02-11 Angel Villar-Corrales , Franziska Schirrmacher , Christian Riess

As the scale and complexity of integrated circuits continue to increase, traditional modeling methods are struggling to address the nonlinear challenges in radio frequency (RF) chips. Deep learning has been increasingly applied to RF device…

Signal Processing · Electrical Eng. & Systems 2024-12-06 Zhaokun Hu , Yindong Xiao , Houjun Wang , Jiayong Yu , Zihang Gao

We propose a simple all-in-line single-shot scheme for diagnostics of ultrashort laser pulses, consisting of a multi-mode fiber, a nonlinear crystal and a CCD camera. The system records a 2D spatial intensity pattern, from which the pulse…

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