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Artificial intelligence (AI), particularly machine learning and deep learning models, has significantly impacted bioinformatics research by offering powerful tools for analyzing complex biological data. However, the lack of interpretability…

Artificial Intelligence · Computer Science 2023-12-12 Zhongliang Zhou , Mengxuan Hu , Mariah Salcedo , Nathan Gravel , Wayland Yeung , Aarya Venkat , Dongliang Guo , Jielu Zhang , Natarajan Kannan , Sheng Li

Clinical adoption of deep learning models has been hindered, in part, because the black-box nature of neural networks leads to concerns regarding their trustworthiness and reliability. These concerns are particularly relevant in the field…

Image and Video Processing · Electrical Eng. & Systems 2024-06-27 Lindsay Munroe , Mariana da Silva , Faezeh Heidari , Irina Grigorescu , Simon Dahan , Emma C. Robinson , Maria Deprez , Po-Wah So

With the availability of large databases and recent improvements in deep learning methodology, the performance of AI systems is reaching or even exceeding the human level on an increasing number of complex tasks. Impressive examples of this…

Artificial Intelligence · Computer Science 2017-08-29 Wojciech Samek , Thomas Wiegand , Klaus-Robert Müller

Explainable Artificial Intelligence (XAI) has emerged as a critical tool for interpreting the predictions of complex deep learning models. While XAI has been increasingly applied in various domains within acoustics, its use in bioacoustics,…

Sound · Computer Science 2025-09-11 Zubair Faruqui , Mackenzie S. McIntire , Rahul Dubey , Jay McEntee

This paper explores the significant impact of AI-based medical devices, including wearables, telemedicine, large language models, and digital twins, on clinical decision support systems. It emphasizes the importance of producing outcomes…

Artificial Intelligence · Computer Science 2024-04-11 Elham Nasarian , Roohallah Alizadehsani , U. Rajendra Acharya , Kwok-Leung Tsui

With the advances in computationally efficient artificial Intelligence (AI) techniques and their numerous applications in our everyday life, there is a pressing need to understand the computational details hidden in black box AI techniques…

Machine Learning · Computer Science 2023-11-13 Mrutyunjaya Panda , Soumya Ranjan Mahanta

Explainable AI (XAI) is widely viewed as a sine qua non for ever-expanding AI research. A better understanding of the needs of XAI users, as well as human-centered evaluations of explainable models are both a necessity and a challenge. In…

Artificial Intelligence · Computer Science 2024-10-17 Yao Rong , Tobias Leemann , Thai-trang Nguyen , Lisa Fiedler , Peizhu Qian , Vaibhav Unhelkar , Tina Seidel , Gjergji Kasneci , Enkelejda Kasneci

EXplainable Artificial Intelligence (XAI) is a vibrant research topic in the artificial intelligence community, with growing interest across methods and domains. Much has been written about the subject, yet XAI still lacks shared…

Artificial Intelligence · Computer Science 2023-06-16 Matteo Rizzo , Alberto Veneri , Andrea Albarelli , Claudio Lucchese , Marco Nobile , Cristina Conati

There is a disconnect between explanatory artificial intelligence (XAI) methods and the types of explanations that are useful for and demanded by society (policy makers, government officials, etc.) Questions that experts in artificial…

Artificial Intelligence · Computer Science 2019-01-23 Leilani H. Gilpin , Cecilia Testart , Nathaniel Fruchter , Julius Adebayo

Natural Language Processing (NLP) has become a cornerstone in many critical sectors, including healthcare, finance, and customer relationship management. This is especially true with the development and use of advanced models such as…

Computation and Language · Computer Science 2025-06-06 Hadi Mohammadi , Ayoub Bagheri , Anastasia Giachanou , Daniel L. Oberski

eXplainable Artificial Intelligence (XAI) is a rapidly progressing field of machine learning, aiming to unravel the predictions of complex models. XAI is especially required in sensitive applications, e.g. in health care, when diagnosis,…

Artificial Intelligence · Computer Science 2023-09-13 Alena Kalyakulina , Igor Yusipov , Alexey Moskalev , Claudio Franceschi , Mikhail Ivanchenko

The recent boom of large language models (LLMs) has re-ignited the hope that artificial intelligence (AI) systems could aid medical diagnosis. Yet despite dazzling benchmark scores, LLM assistants have yet to deliver measurable improvements…

Artificial Intelligence · Computer Science 2025-07-03 Matthew JY Kang , Wenli Yang , Monica R Roberts , Byeong Ho Kang , Charles B Malpas

The growing number of AI applications, also for high-stake decisions, increases the interest in Explainable and Interpretable Machine Learning (XI-ML). This trend can be seen both in the increasing number of regulations and strategies for…

Explainable Artificial Intelligence (XAI) is an emerging research field bringing transparency to highly complex and opaque machine learning (ML) models. Despite the development of a multitude of methods to explain the decisions of black-box…

Machine Learning · Computer Science 2022-03-16 Leander Weber , Sebastian Lapuschkin , Alexander Binder , Wojciech Samek

Artificial intelligence (AI) enables machines to learn from human experience, adjust to new inputs, and perform human-like tasks. AI is progressing rapidly and is transforming the way businesses operate, from process automation to cognitive…

Machine Learning · Computer Science 2021-12-17 Ambreen Hanif

Explainable Artificial Intelligence (XAI) plays a crucial role in fostering transparency and trust in AI systems, where traditional XAI approaches typically offer one level of abstraction for explanations, often in the form of heatmaps…

With the broader and highly successful usage of machine learning in industry and the sciences, there has been a growing demand for Explainable AI. Interpretability and explanation methods for gaining a better understanding about the problem…

Machine Learning · Computer Science 2021-02-26 Wojciech Samek , Grégoire Montavon , Sebastian Lapuschkin , Christopher J. Anders , Klaus-Robert Müller

The increasing complexity of AI systems has led to the growth of the field of Explainable Artificial Intelligence (XAI), which aims to provide explanations and justifications for the outputs of AI algorithms. While there is considerable…

Artificial Intelligence · Computer Science 2024-06-21 Maryam Hashemi , Ali Darejeh , Francisco Cruz

Artificial Intelligence has emerged as a useful aid in numerous clinical applications for diagnosis and treatment decisions. Deep neural networks have shown same or better performance than clinicians in many tasks owing to the rapid…

Image and Video Processing · Electrical Eng. & Systems 2021-11-05 Zohaib Salahuddin , Henry C Woodruff , Avishek Chatterjee , Philippe Lambin