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Large Language Models (LLMs) have played a pivotal role in advancing Artificial Intelligence (AI). However, despite their achievements, LLMs often struggle to explain their decision-making processes, making them a 'black box' and presenting…

Computation and Language · Computer Science 2025-06-30 Avash Palikhe , Zhenyu Yu , Zichong Wang , Wenbin Zhang

In this survey, we address the key challenges in Large Language Models (LLM) research, focusing on the importance of interpretability. Driven by increasing interest from AI and business sectors, we highlight the need for transparency in…

Computation and Language · Computer Science 2024-07-23 Erik Cambria , Lorenzo Malandri , Fabio Mercorio , Navid Nobani , Andrea Seveso

We often use "explainable" Artificial Intelligence (XAI)" and "interpretable AI (IAI)" interchangeably when we apply various XAI tools for a given dataset to explain the reasons that underpin machine learning (ML) outputs. However, these…

Artificial Intelligence · Computer Science 2024-08-23 Caesar Wu , Rajkumar Buyya , Yuan Fang Li , Pascal Bouvry

Nowadays, deep neural networks are widely used in mission critical systems such as healthcare, self-driving vehicles, and military which have direct impact on human lives. However, the black-box nature of deep neural networks challenges its…

Computer Vision and Pattern Recognition · Computer Science 2020-06-24 Arun Das , Paul Rad

Explainable AI (XAI) is a necessity in safety-critical systems such as in clinical diagnostics due to a high risk for fatal decisions. Currently, however, XAI resembles a loose collection of methods rather than a well-defined process. In…

Computer Vision and Pattern Recognition · Computer Science 2022-07-12 Lukas Klein , Mennatallah El-Assady , Paul F. Jäger

Explainable artificial intelligence (XAI) has become increasingly important in biomedical image analysis to promote transparency, trust, and clinical adoption of DL models. While several surveys have reviewed XAI techniques, they often lack…

Computer Vision and Pattern Recognition · Computer Science 2025-07-11 Getamesay Haile Dagnaw , Yanming Zhu , Muhammad Hassan Maqsood , Wencheng Yang , Xingshuai Dong , Xuefei Yin , Alan Wee-Chung Liew

Recent advancements in artificial intelligence (AI) have facilitated its widespread adoption in primary medical services, addressing the demand-supply imbalance in healthcare. Vision Transformers (ViT) have emerged as state-of-the-art…

Computer Vision and Pattern Recognition · Computer Science 2023-09-04 Tin Lai

Artificial intelligence (AI) systems utilizing deep neural networks (DNNs) and machine learning (ML) algorithms are widely used for solving important problems in bioinformatics, biomedical informatics, and precision medicine. However,…

Quantitative Methods · Quantitative Biology 2023-02-24 Md. Rezaul Karim , Tanhim Islam , Oya Beyan , Christoph Lange , Michael Cochez , Dietrich Rebholz-Schuhmann , Stefan Decker

Explainable Artificial Intelligence (XAI) aims to uncover the inner reasoning of machine learning models. In IoT systems, XAI improves the transparency of models processing sensor data from multiple heterogeneous devices, ensuring end-users…

Computation and Language · Computer Science 2025-08-22 Michele Fiori , Gabriele Civitarese , Priyankar Choudhary , Claudio Bettini

XAI refers to the techniques and methods for building AI applications which assist end users to interpret output and predictions of AI models. Black box AI applications in high-stakes decision-making situations, such as medical domain have…

The growing application of artificial intelligence in sensitive domains has intensified the demand for systems that are not only accurate but also explainable and trustworthy. Although explainable AI (XAI) methods have proliferated, many do…

Artificial Intelligence · Computer Science 2026-01-06 Marilyn Bello , Rafael Bello , Maria-Matilde García , Ann Nowé , Iván Sevillano-García , Francisco Herrera

Deep neural networks form the backbone of artificial intelligence research, with potential to transform the human experience in areas ranging from autonomous driving to personal assistants, healthcare to education. However, their…

Machine Learning · Computer Science 2025-05-29 Vinitra Swamy

Artificial intelligence (AI) is increasingly permeating healthcare, from physician assistants to consumer applications. Since AI algorithm's opacity challenges human interaction, explainable AI (XAI) addresses this by providing AI…

The growing adoption of artificial intelligence in healthcare has raised concerns about the transparency and trustworthiness of AI-driven medical diagnosis systems. Many existing models operate as black boxes, limiting clinicians' ability…

Human-Computer Interaction · Computer Science 2026-04-21 Altynbek Seitenov , Ainur Nurzhanova , Azhar Bekbussinova , Yerassyl Bolatkan

Language Models (LMs) have significantly advanced natural language processing and enabled remarkable progress across diverse domains, yet their black-box nature raises critical concerns about the interpretability of their internal…

Computation and Language · Computer Science 2025-09-29 Avash Palikhe , Zichong Wang , Zhipeng Yin , Rui Guo , Qiang Duan , Jie Yang , Wenbin Zhang

As machine learning models become increasingly prevalent in medical diagnostics, the need for interpretability and transparency becomes paramount. The XAI Renaissance signifies a significant shift in the field, aiming to redefine the…

Machine Learning · Computer Science 2023-06-05 Sujith K Mandala

With an increase in deep learning-based methods, the call for explainability of such methods grows, especially in high-stakes decision making areas such as medical image analysis. This survey presents an overview of eXplainable Artificial…

Image and Video Processing · Electrical Eng. & Systems 2022-05-06 Bas H. M. van der Velden , Hugo J. Kuijf , Kenneth G. A. Gilhuijs , Max A. Viergever

Explainable artificial intelligence (XAI) plays an indispensable role in demystifying the decision-making processes of AI, especially within the healthcare industry. Clinicians rely heavily on detailed reasoning when making a diagnosis,…

Computer Vision and Pattern Recognition · Computer Science 2024-03-26 Anna Stubbin , Thompson Chyrikov , Jim Zhao , Christina Chajo

Explainable Artificial Intelligence (XAI) is an emerging field in AI that aims to address the opaque nature of machine learning models. Furthermore, it has been shown that XAI can be used to extract input-output relationships, making them a…

Chemical Physics · Physics 2023-11-08 Geemi P. Wellawatte , Philippe Schwaller

In recent years, deep learning has achieved unprecedented success in various computer vision tasks, particularly in object detection. However, the black-box nature and high complexity of deep neural networks pose significant challenges for…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 FatemehSadat Seyedmomeni , Mohammad Ali Keyvanrad