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Microscopy image analysis often requires the segmentation of objects, but training data for this task is typically scarce and hard to obtain. Here we propose DenoiSeg, a new method that can be trained end-to-end on only a few annotated…

Computer Vision and Pattern Recognition · Computer Science 2020-06-12 Tim-Oliver Buchholz , Mangal Prakash , Alexander Krull , Florian Jug

Optical neuroimaging is a vital tool for understanding the brain structure and the connection between regions and nuclei. However, the image noise introduced in the sample preparation and the imaging system hinders the extraction of the…

Image and Video Processing · Electrical Eng. & Systems 2021-09-23 Tianfang Zhu , Yue Guan , Anan Li

Fluorescence microscopy is a key driver to promote discoveries of biomedical research. However, with the limitation of microscope hardware and characteristics of the observed samples, the fluorescence microscopy images are susceptible to…

Image and Video Processing · Electrical Eng. & Systems 2022-09-15 Xuanyu Tian , Qing Wu , Hongjiang Wei , Yuyao Zhang

Noisy images are a challenge to image compression algorithms due to the inherent difficulty of compressing noise. As noise cannot easily be discerned from image details, such as high-frequency signals, its presence leads to extra bits…

Image and Video Processing · Electrical Eng. & Systems 2024-02-09 Yuxin Xie , Li Yu , Farhad Pakdaman , Moncef Gabbouj

Though achieving excellent performance in some cases, current unsupervised learning methods for single image denoising usually have constraints in applications. In this paper, we propose a new approach which is more general and applicable…

Computer Vision and Pattern Recognition · Computer Science 2023-04-18 Yutong Xie , Mingze Yuan , Bin Dong , Quanzheng Li

Image denoising is of great importance for medical imaging system, since it can improve image quality for disease diagnosis and downstream image analyses. In a variety of applications, dynamic imaging techniques are utilized to capture the…

Image and Video Processing · Electrical Eng. & Systems 2021-06-24 Junshen Xu , Elfar Adalsteinsson

Many microscopy applications are limited by the total amount of usable light and are consequently challenged by the resulting levels of noise in the acquired images. This problem is often addressed via (supervised) deep learning based…

Image and Video Processing · Electrical Eng. & Systems 2020-08-20 Anna S. Goncharova , Alf Honigmann , Florian Jug , Alexander Krull

Reliable analysis of intracellular dynamic processes in time-lapse fluorescence microscopy images requires complete and accurate tracking of all small particles in all time frames of the image sequences. A fundamental first step towards…

Image and Video Processing · Electrical Eng. & Systems 2024-08-16 Yao Yao , Ihor Smal , Ilya Grigoriev , Anna Akhmanova , Erik Meijering

High levels of noise usually exist in today's captured images due to the relatively small sensors equipped in the smartphone cameras, where the noise brings extra challenges to lossy image compression algorithms. Without the capacity to…

Image and Video Processing · Electrical Eng. & Systems 2022-07-25 Ka Leong Cheng , Yueqi Xie , Qifeng Chen

This article addresses the image denoising problem in the situations of strong noise. We propose a dual sparse decomposition method. This method makes a sub-dictionary decomposition on the over-complete dictionary in the sparse…

Computer Vision and Pattern Recognition · Computer Science 2017-04-25 Hong Sun , Chen-guang Liu , Cheng-wei Sang

Patient scans from MRI often suffer from noise, which hampers the diagnostic capability of such images. As a method to mitigate such artifact, denoising is largely studied both within the medical imaging community and beyond the community…

Image and Video Processing · Electrical Eng. & Systems 2022-03-25 Hyungjin Chung , Eun Sun Lee , Jong Chul Ye

Image denoising is a fundamental task in low-level computer vision. While recent deep learning-based image denoising methods have achieved impressive performance, they are black-box models and the underlying denoising principle remains…

Computer Vision and Pattern Recognition · Computer Science 2023-09-27 Jingwei Niu , Jun Cheng , Shan Tan

In the last few years, with the rapid development of deep learning technologies, supervised methods based on convolutional neural networks have greatly enhanced the performance of medical image denoising. However, these methods require…

Image and Video Processing · Electrical Eng. & Systems 2025-03-10 Langrui Zhou , Ziteng Zhou , Xinyu Huang , Huiru Wang , Xiangyu Zhang , Guang Li

Image denoising is a prerequisite for downstream tasks in many fields. Low-dose and photon-counting computed tomography (CT) denoising can optimize diagnostic performance at minimized radiation dose. Supervised deep denoising methods are…

Machine Learning · Computer Science 2022-01-06 Chuang Niu , Mengzhou Li , Fenglei Fan , Weiwen Wu , Xiaodong Guo , Qing Lyu , Ge Wang

Image denoising is a typical ill-posed problem due to complex degradation. Leading methods based on normalizing flows have tried to solve this problem with an invertible transformation instead of a deterministic mapping. However, the…

Computer Vision and Pattern Recognition · Computer Science 2023-02-01 Wenchao Du , Hu Chen , Yi Zhang , H. Yang

In fluorescence microscopy, spectral unmixing aims to recover individual fluorophore concentrations from spectral images that capture mixed fluorophore emissions. Since classical methods operate pixel-wise and rely on least-squares fitting,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-26 Federico Carrara , Talley Lambert , Mehdi Seifi , Florian Jug

Medical image denoising is considered among the most challenging vision tasks. Despite the real-world implications, existing denoising methods have notable drawbacks as they often generate visual artifacts when applied to heterogeneous…

Image and Video Processing · Electrical Eng. & Systems 2025-03-11 S M A Sharif , Rizwan Ali Naqvi , Woong-Kee Loh

Currently, many blind deblurring methods assume blurred images are noise-free and perform unsatisfactorily on the blurry images with noise. Unfortunately, noise is quite common in real scenes. A straightforward solution is to denoise images…

Computer Vision and Pattern Recognition · Computer Science 2020-01-28 Si Miao , Yongxin Zhu

During the acquisition of an image from its source, noise always becomes an integral part of it. Various algorithms have been used in past to denoise the images. Image denoising still has scope for improvement. Visual information…

Image and Video Processing · Electrical Eng. & Systems 2019-09-17 Santosh Paudel , Ajay Kumar Shrestha , Pradip Singh Maharjan , Rameshwar Rijal

The capability of image semantic segmentation may be deteriorated due to noisy input image, where image denoising prior to segmentation helps. Both image denoising and semantic segmentation have been developed significantly with the advance…

Computer Vision and Pattern Recognition · Computer Science 2021-02-25 Shunxin Xu , Ke Sun , Dong Liu , Zhiwei Xiong , Zheng-Jun Zha
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