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Multicellular systems play a key role in bioprocess and biomedical engineering. Cell ensembles encountered in these setups show phenotypic variability like size and biochemical composition. As this variability may result in undesired…

Systems and Control · Computer Science 2018-07-16 Armin Küper , Robert Dürr , Steffen Waldherr

It is highly desirable to borrow information from external data to augment a control arm in a randomized clinical trial, especially in settings where the sample size for the control arm is limited. However, a main challenge in borrowing…

Methodology · Statistics 2023-11-01 Dehua Bi , Tianjian Zhou , Wei Zhong , Yuan Ji

The Half-Space Matching (HSM) method has recently been developed as a new method for the solution of 2D scattering problems with complex backgrounds, providing an alternative to Perfectly Matched Layers (PML) or other artificial boundary…

The Smoluchowski's aggregation equation has applications in the field of bio-pharmaceuticals \cite{zidar2018characterisation}, financial sector \cite{PUSHKIN2004571}, aerosol science \cite{shen2020efficient} and many others. Several…

Numerical Analysis · Mathematics 2022-08-08 Sonali Kaushik , Rajesh Kumar

We explore a few-fermion mixture consisting of two components which are repulsively interacting and confined in a one-dimensional harmonic trap. Different scenarios of population imbalance ranging from the completely imbalanced case where…

Quantum Gases · Physics 2015-06-11 Ioannis Brouzos , Peter Schmelcher

We consider a partially linear framework for modelling massive heterogeneous data. The major goal is to extract common features across all sub-populations while exploring heterogeneity of each sub-population. In particular, we propose an…

Statistics Theory · Mathematics 2016-01-26 Tianqi Zhao , Guang Cheng , Han Liu

The population annealing algorithm introduced by Hukushima and Iba is described. Population annealing combines simulated annealing and Boltzmann weighted differential reproduction within a population of replicas to sample equilibrium…

Statistical Mechanics · Physics 2015-03-17 Jon Machta

In recent years, with the rapid development of science and technology, heterogeneous treatment effects have emerged as a focal research topic in statistics, econometrics, and sociology. This paper investigates HTE through semiparametric…

Methodology · Statistics 2025-07-21 Jichang Yu , Wenjing Chang , Peichao Yu , Lijun Chen , Yuanshan Wu

In the present work, we use the homotopy perturbation method (HPM) to solve the Newell- Whitehead-Segel non-linear differential equations. Four case study problems of Newell-Whitehead- Segel are solved by the HPM and the exact solutions are…

General Mathematics · Mathematics 2015-03-02 S. Salman Nourazar , Mohsen Soori , Akbar Nazari-Golshan

Semi-supervised clustering is the task of clustering data points into clusters where only a fraction of the points are labelled. The true number of clusters in the data is often unknown and most models require this parameter as an input.…

Machine Learning · Computer Science 2013-09-27 Amar Shah , Zoubin Ghahramani

We consider the problem of causal structure learning in the setting of heterogeneous populations, i.e., populations in which a single causal structure does not adequately represent all population members, as is common in biological and…

Machine Learning · Statistics 2022-02-21 Alex Markham , Richeek Das , Moritz Grosse-Wentrup

The alpha-cluster states of $^{22}$Ne are studied within the framework of the semimicroscopic algebraic cluster model (SACM). The band structure, energy spectrum as well as E2 and E1 transitions are calculated and are compared with the…

Nuclear Theory · Physics 2015-06-16 G. Lévai

Motivated by structured parasite populations in aquaculture we consider a class of size-structured population models, where individuals may be recruited into the population with distributed states at birth. The mathematical model which…

Analysis of PDEs · Mathematics 2019-03-25 Jozsef Z. Farkas , Darren Green , Peter Hinow

A full parametric and linear specification may be insufficient to capture complicated patterns in studies exploring complex features, such as those investigating age-related changes in brain functional abilities. Alternatively, a partially…

Methodology · Statistics 2024-02-07 Jia Liang , Shuo Chen , Peter Kochunov , L Elliot Hong , Chixiang Chen

Partially recorded data are frequently encountered in many applications and usually clustered by first removing incomplete cases or features with missing values, or by imputing missing values, followed by application of a clustering…

Methodology · Statistics 2021-10-20 Emily M. Goren , Ranjan Maitra

Clustering high-dimensional data is especially challenging when cluster distributions are heavy tailed and only approximately elliptical. Existing high-dimensional methods are largely built for Gaussian or other light-tailed models, whereas…

Methodology · Statistics 2026-05-12 Long Feng , Dan Zhuang

Kernel-based methods have been recently introduced for linear system identification as an alternative to parametric prediction error methods. Adopting the Bayesian perspective, the impulse response is modeled as a non-stationary Gaussian…

Optimization and Control · Mathematics 2017-03-16 Mattia Zorzi , Alessandro Chiuso

We consider an additive partially linear framework for modelling massive heterogeneous data. The major goal is to extract multiple common features simultaneously across all sub-populations while exploring heterogeneity of each…

Methodology · Statistics 2019-01-01 Binhuan Wang , Yixin Fang , Heng Lian , Hua Liang

We consider the problem of clustering nested or hierarchical data, where observations are grouped and there are both group-level and observation-level variables. In our motivating OneK1K dataset, observations consist of single-cell…

Methodology · Statistics 2026-04-14 Arhit Chakrabarti , Yang Ni , Yuchao Jiang , Bani K. Mallick

We introduce a novel statistical significance-based approach for clustering hierarchical data using semi-parametric linear mixed-effects models designed for responses with laws in the exponential family (e.g., Poisson and Bernoulli). Within…

Methodology · Statistics 2025-02-04 Alessandra Ragni , Chiara Masci , Francesca Ieva , Anna Maria Paganoni