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Effect modification occurs when the effect of the treatment on an outcome differs according to the level of a third variable (the effect modifier, EM). A natural way to assess effect modification is by subgroup analysis or include the…

Methodology · Statistics 2021-12-22 Asma Bahamyirou , Mireille E. Schnitzer , Edward H. Kennedy , Lucie Blais , Yi Yang

Statistical methods for identifying harmful chemicals in a correlated mixture often assume linearity in exposure-response relationships. Non-monotonic relationships are increasingly recognised (e.g., for endocrine-disrupting chemicals);…

Applications · Statistics 2020-11-11 Nina Lazarevic , Luke D. Knibbs , Peter D. Sly , Adrian G. Barnett

Recent work found that LLMs are sensitive to a wide range of arbitrary prompt dimensions, including the type of delimiters, answer enumerators, instruction wording, and more. This throws into question popular single-prompt evaluation…

Computation and Language · Computer Science 2026-04-07 Eliya Habba , Ofir Arviv , Itay Itzhak , Yotam Perlitz , Elron Bandel , Leshem Choshen , Michal Shmueli-Scheuer , Gabriel Stanovsky

This study develops a generalised multi-objective, multi-echelon supply chain optimisation model with non-stationary markets based on a Markov decision process, incorporating economic, environmental, and social considerations. The model is…

Artificial Intelligence · Computer Science 2025-07-29 Rifny Rachman , Josh Tingey , Richard Allmendinger , Pradyumn Shukla , Wei Pan

Cancer drug response prediction (DRP) models present a promising approach towards precision oncology, tailoring treatments to individual patient profiles. While deep learning (DL) methods have shown great potential in this area, models that…

This study focuses on the novel municipal-scale rural integrated energy system (RIES), which encompasses energy supply and application. By constructing a seven-dimensional evaluation system including energy efficiency, energy supply,…

Systems and Control · Electrical Eng. & Systems 2025-06-19 Ruonan Lia , Chang Wena , Mingyu Yan , Congcong Wu , Ahmed Lotfy Elrefai , Xiaotong Zhang , Sahban Wael Saeed Alnaser

Lead optimization in drug discovery requires improving therapeutic properties while ensuring that molecular modifications correspond to feasible synthetic routes. Existing approaches either prioritize property scores without enforcing…

Machine Learning · Computer Science 2026-05-04 Tao Li , Kaiyuan Hou , Tuan Vinh , Monika Raj , Zhichun Guo , Carl Yang

A large number of multi-attribute group decisionmaking (MAGDM) have been widely introduced to obtain consensus results. However, most of the methodologies ignore the conflict among the experts opinions and only consider equal or variable…

Artificial Intelligence · Computer Science 2024-09-16 Pragya Gupta , Debjani Chakraborty , Debashree Guha

Recent advancements in Multimodal Emotion Recognition (MER) face challenges in addressing both modality missing and Out-Of-Distribution (OOD) data simultaneously. Existing methods often rely on specific models or introduce excessive…

Computer Vision and Pattern Recognition · Computer Science 2025-06-13 Guowei Zhong , Ruohong Huan , Mingzhen Wu , Ronghua Liang , Peng Chen

When addressing the challenge of complex multi-objective optimization problems, particularly those with non-convex and non-uniform Pareto fronts, Decomposition-based Multi-Objective Evolutionary Algorithms (MOEADs) often converge to local…

Neural and Evolutionary Computing · Computer Science 2024-04-15 Ting Dong , Haoxin Wang , Hengxi Zhang , Wenbo Ding

We introduceDropDim, a structured dropout method designed for regularizing the self-attention mechanism, which is a key component of the transformer. In contrast to the general dropout method, which randomly drops neurons, DropDim drops…

Computation and Language · Computer Science 2023-04-21 Hao Zhang , Dan Qu , Keji Shao , Xukui Yang

While traditional Deep Learning (DL) optimization methods treat all training samples equally, Distributionally Robust Optimization (DRO) adaptively assigns importance weights to different samples. However, a significant gap exists between…

This paper investigates a series of optimization problems for one-counter Markov decision processes (MDPs) and integer-weighted MDPs with finite state space. Specifically, it considers problems addressing termination probabilities and…

Logic in Computer Science · Computer Science 2024-08-07 Jakob Piribauer , Christel Baier

Randomized controlled trials (RCT's) allow researchers to estimate causal effects in an experimental sample with minimal identifying assumptions. However, to generalize or transport a causal effect from an RCT to a target population,…

Methodology · Statistics 2022-02-08 Melody Huang

Recent advances in large-scale language models (LLMs) have made multi-agent architectures attractive for challenging reasoning tasks. However, many existing systems rely on stochastic routing or ad-hoc heuristics, making their behavior…

Artificial Intelligence · Computer Science 2026-02-03 Hanlin Zhou , Huah Yong Chan

Post-training has significantly enhanced the reasoning capability of Large Reasoning Models (LRMs), especially with Reinforcement Learning (RL) like Group Relative Policy Optimization (GRPO). However, GRPO-style RL methods in multi-domain…

Computation and Language · Computer Science 2026-05-26 Zongji Yu , Wenshui Luo , Yiliu Sun , Hao Fang , Runmin Cong , Chaochao Lu , Chen Gong

Different distribution shifts require different interventions, and algorithms must be grounded in the specific shifts they address. However, methodological development for robust algorithms typically relies on structural assumptions that…

Machine Learning · Computer Science 2025-08-27 Tianyu Wang , Jiashuo Liu , Peng Cui , Hongseok Namkoong

In this paper, the minimization of computational cost on evaluating multi-dimensional integrals is explored. More specifically, a method based on an adaptive scheme for error variance selection in Monte Carlo integration (MCI) is presented.…

Numerical Analysis · Mathematics 2019-06-27 Felipe Carraro , Rafael Holdorf Lopez , Leandro Fleck Fadel Miguel , André Jacomel Torii

We made a comparative analysis of numerical methods for multidimensional optimization. The main parameter is a number of computations of the test function to reach necessary accuracy, as it is computationally "slow". For complex functions,…

Instrumentation and Methods for Astrophysics · Physics 2013-10-09 Ivan L. Andronov , Maria G. Tkachenko

Global Sensitivity Analysis (GSA) is the study of the influence of any given inputs on the outputs of a model. In the context of engineering design, GSA has been widely used to understand both individual and collective contributions of…

Machine Learning · Statistics 2024-03-06 Yigitcan Comlek , Liwei Wang , Wei Chen